William W. Greenfield

Professor

UAMS

Also affiliated: Arkansas Children's Hospital (2014); Arkansas Department of Agriculture (2015); Arkansas Department of Health (2024); Beijing Obstetrics and Gynecology Hospital (2007)

Faculty Researcher

Obstetrics & Gynecology, College of Medicine

11 h-index 27 pubs 413 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website Research Group UAMS TRI Profile

OverviewAI-generated summary

Dr. William W. Greenfield's research focuses on human papillomavirus (HPV) infections, particularly in relation to cervical intraepithelial neoplasia (CIN) and cervical cancer. His work has investigated the evaluation of DNA extraction protocols from cytology specimens for studying cervical microbiota and has explored therapeutic vaccine approaches, such as the peptide-based HPV therapeutic vaccine PepCan, in clinical trials for treating CIN2/3. He has also examined the immune responses generated by these therapeutic interventions. Dr. Greenfield's research interests extend to maternal health, including the assessment of public maternal health dashboards in the United States and personal birth experiences among labor and delivery staff. His background includes a pharmacy degree from Auburn University and extensive training in obstetrics and gynecology, including da Vinci Robotic Surgery. He holds an h-index of 11 with 27 publications and 407 citations, and he collaborates with researchers at the University of Arkansas for Medical Sciences.

Research Overview

Dr. William Greenfield completed his medical degree at Meharry Medical College in Nashville, Tennessee, completed an internship at Baylor College of Medicine in Houston, Texas, and his residency in Obstetrics and Gynecology at the University of Arkansas for Medical Sciences in Little Rock. Before attending medical school, he received a pharmacy degree from Auburn University. His clinical interests are in obstetrics and gynecology. He is trained in daVinci Robotic Surgery. He has made presentations nationally, regionally and locally on topics in his field. Dr. Greenfield currently serves as the Arkansas Section Chair for the American Congress of Obstetrics and Gynecology, and is a member of several professional organizations including:Arkansas Medical SocietyAmerican Medical AssociationAmerican Society of Colposcopy and Cervical PathologyDr. Greenfield enjoys both his obstetric and gynecologic patients. He likes to help educate his patients and guide them to make informed decisions about their healthcare.

Metrics

h-index: 11
Publications: 27
Citations: 413

Selected Publications

Maternity Care Team Members’ Perspectives on Barriers and Facilitators to Integrating Doulas into the Hospital Setting (2026)

MCN The American Journal of Maternal/Child Nursing DOI OpenAlex
Personal Birth Experiences and Clinician Attitudes About Cesarean Birth: A Cross‐Sectional Study With Female Labor and Delivery Unit Staff (2026)

Birth DOI OpenAlex
A Randomized Double-Blind Phase 2 Clinical Trial Treating Cervical Intraepithelial Neoplasia 2/3 with PepCan or Candida (2025)

medRxiv 3 citations DOI OpenAlex
Immune responses in a phase 2 clinical trial of peptide-based therapeutic human papillomavirus vaccine, PepCan, versus Candida adjuvant alone in treating cervical intraepithelial neoplasia 2/3. (2024)

Journal of Clinical Oncology 1 citation DOI OpenAlex
Public Maternal Health Dashboards in the United States: Descriptive Assessment (2024)

Journal of Medical Internet Research 2 citations DOI OpenAlex
Maternal Mortality Review Committee findings: awareness and recommended dissemination strategies in Arkansas (2024)

AJOG Global Reports DOI OpenAlex
A peptide-based human papillomavirus therapeutic vaccine, PepCan, or Candida adjuvant alone in treatment of cervical intraepithelial neoplasia 2/3 (CIN2/3). (2023)

Journal of Clinical Oncology 2 citations DOI OpenAlex
Quarantine and isolation facility: A State Health Department’s response to the COVID-19 pandemic (2021)

American Journal of Disaster Medicine 1 citation DOI OpenAlex
Evaluation of DNA extraction protocols from liquid-based cytology specimens for studying cervical microbiota (2021)

PLoS ONE 11 citations DOI OpenAlex
Evaluation of DNA extraction protocols from liquid-based cytology specimens for studying cervical microbiota (2020)

bioRxiv (Cold Spring Harbor Laboratory) 4 citations DOI OpenAlex
Cervical Microbiome and Response to a Human Papillomavirus Therapeutic Vaccine for Treating High-Grade Cervical Squamous Intraepithelial Lesion (2019)

Integrative Cancer Therapies 16 citations DOI OpenAlex
Cervical microbiome role in outcomes of therapeutic HPV vaccination for cervical intraepithelial neoplasia. (2018)

Journal of Clinical Oncology 3 citations DOI OpenAlex
Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination (2016)

Cancer Immunology Immunotherapy 63 citations DOI OpenAlex
A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3. (2015)

Journal of Clinical Oncology DOI OpenAlex
A novel use of a statewide telecolposcopy network for recruitment of participants in a Phase I clinical trial of a human papillomavirus therapeutic vaccine (2015)

Clinical Trials 12 citations DOI OpenAlex

View all publications on OpenAlex →

Grants & Funding

As listed on this researcher's institutional profile.

DP24-004, PRC, Core: Health Promotion and Disease Prevention Research Centers NIH Co-Investigator
Understanding and Enhancing T-Cell Responses to High Risk Human Papillomaviruses-Renewal NIH Co-Investigator
The Arkansas Perinatal Quality Collaborative Centers for Disease Control & Prevention Co-Principal Investigator