Xuehua Li
Post Doctoral Fellow
Also affiliated: North Sichuan Medical University (2025); Nanjing University of Chinese Medicine (2012); Capital University (2021); Capital Medical University (2021); Southwest Medical University (2025); Affiliated Hospital of Southwest Medical University (2025); Meizhou City People's Hospital (2009); Shuozhou Central Hospital (2021); Yunnan Center for Disease Control And Prevention (2012–2023); Chengdu University (2023); Beijing Friendship Hospital (2021); Nanchong Central Hospital (2024)
Postdoc Researcher
Orthopaedics Surgery, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Xuehua Li's research investigates mechanisms underlying disease and injury, with a focus on molecular signaling pathways. Li has published work examining how low-dose lipopolysaccharide (LPS) can alleviate early brain injury following subarachnoid hemorrhage by modulating microglial polarization through the USP19/FOXO1/IL-10/IL-10R1 signaling cascade. Other studies explore how Piezo1 stimulates mitochondrial function via cAMP signaling and how glycyrrhizic acid mitigates acute lung injury in neonatal rats by inhibiting oxidative stress through the Keap1/Nrf2/HO-1 pathway. Li also researches bone health, including mitigating aging and doxorubicin-induced bone loss in mice through mechanobiology-based treatments. Additionally, Li has contributed to research on wound healing using chitosan/polysaccharide composite films derived from insect residues, and has datasets on the effects of psychological care on depression and suicide ideation in children. Li's work involves collaborations with researchers at the University of Arkansas for Medical Sciences, including Jinhu Xiong and Jacob Kordsmeier.
Metrics
- h-index: 9
- Publications: 15
- Citations: 259
Selected Publications
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Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice (2025)
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Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments (2024)
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Piezo1 stimulates mitochondrial function via <scp>cAMP</scp> signaling (2022)
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New Advances in Osteocyte Mechanotransduction (2021)
Grants & Funding
As listed on this researcher's institutional profile.
- The role of Piezo 1 in bone homeostasis and mechanotransduction NIH/Nat. Inst. of Arthritis & Musculoskeletal & Skin Diseases Co-Investigator
Collaboration Network
Top Collaborators
- New Advances in Osteocyte Mechanotransduction
- Piezo1 stimulates mitochondrial function via <scp>cAMP</scp> signaling
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
- New Advances in Osteocyte Mechanotransduction
- Piezo1 stimulates mitochondrial function via <scp>cAMP</scp> signaling
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
- Piezo1 stimulates mitochondrial function via <scp>cAMP</scp> signaling
- Piezo1 stimulates mitochondrial function via <scp>cAMP</scp> signaling
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
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