X
Xuehua Li
Post Doctoral Fellow
postdoc
Orthopaedics Surgery, College of Medicine
8 h-index
15 pubs
232 cited
Research Areas
Biography and Research Information
OverviewAI-generated summary
Xuehua Li's research focuses on understanding biological mechanisms relevant to health and disease, with a particular emphasis on bone health, inflammation, and wound healing. Li has investigated the role of mechanotransduction in osteocytes and the impact of Piezo1 on mitochondrial function. Their work also explores therapeutic interventions for conditions such as acute lung injury and age-related bone loss, examining signaling pathways like Keap1/Nrf2/HO-1 and USP19/FOXO1/IL-10/IL-10R1.
Recent publications include studies on mitigating aging and doxorubicin-induced bone loss in mice using mechanobiology-based treatments and the development of chitosan/polysaccharide composite films from insect residues for wound healing applications. These films exhibit antioxidant and anti-inflammatory properties. Li has also contributed to research on early brain injury following subarachnoid hemorrhage and the effects of psychological care on depression and suicide ideation in children.
Metrics
- h-index: 8
- Publications: 15
- Citations: 232
Selected Publications
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Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice (2025)
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Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments (2024)
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Piezo1 stimulates mitochondrial function via <scp>cAMP</scp> signaling (2022)
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New Advances in Osteocyte Mechanotransduction (2021)
Grants & Funding
- The role of Piezo 1 in bone homeostasis and mechanotransduction NIH/Nat. Inst. of Arthritis & Musculoskeletal & Skin Diseases Co-Investigator
Collaboration Network
Top Collaborators
Jinhu Xiong
University of Arkansas for Medical Sciences
4 shared publications
In database
- New Advances in Osteocyte Mechanotransduction
- Piezo1 stimulates mitochondrial function via <scp>cAMP</scp> signaling
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
Jacob Kordsmeier
University of Arkansas for Medical Sciences
2 shared publications
In database
- New Advances in Osteocyte Mechanotransduction
- Piezo1 stimulates mitochondrial function via <scp>cAMP</scp> signaling
Yali Liu
Chengdu University (CN)
2 shared publications
- Antioxidant, antibacterial, and anti-inflammatory Periplaneta americana remnant chitosan/polysaccharide composite film: In vivo wound healing application evaluation
- A polysaccharide/chitin hydrogel wound dressing from a <i>Periplanattica americana</i> residue: coagulation, antioxidant activity, and wound healing properties
Song Qin
Chengdu University (CN)
2 shared publications
- Antioxidant, antibacterial, and anti-inflammatory Periplaneta americana remnant chitosan/polysaccharide composite film: In vivo wound healing application evaluation
- A polysaccharide/chitin hydrogel wound dressing from a <i>Periplanattica americana</i> residue: coagulation, antioxidant activity, and wound healing properties
Murtaza Wasi
University of Delaware (US)
2 shared publications
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
Tiankuo Chu
University of Delaware (US)
2 shared publications
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
Rosa M Guerra
University of Delaware (US)
2 shared publications
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
Rory Kooker
University of Delaware (US)
2 shared publications
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
Xin Song
University of Toronto (CA)
2 shared publications
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
Lidan You
University of Toronto (CA)
2 shared publications
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
Liyun Wang
University of Delaware (US)
2 shared publications
- Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments
- Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice
Linhan Zhu
Capital Medical University (CN)
1 shared publication
- Glycyrrhizic acid alleviates the meconium-induced acute lung injury in neonatal rats by inhibiting oxidative stress through mediating the Keap1/Nrf2/HO-1 signal pathway
Meichen Wei
Capital University (US)
1 shared publication
- Glycyrrhizic acid alleviates the meconium-induced acute lung injury in neonatal rats by inhibiting oxidative stress through mediating the Keap1/Nrf2/HO-1 signal pathway
Nan Yang
Capital University (US)
1 shared publication
- Glycyrrhizic acid alleviates the meconium-induced acute lung injury in neonatal rats by inhibiting oxidative stress through mediating the Keap1/Nrf2/HO-1 signal pathway
Huimin Li
Shuozhou Central Hospital (CN)
1 shared publication
- G‐CSF as a potential early biomarker for diagnosis of bloodstream infection
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