Young Hye Song

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI

Assistant Professor

University of Arkansas

Also affiliated: Cornell University (2013–2020); Konkuk University (2025); University of Florida (2018–2022); Konkuk University Medical Center (2021–2025); Gainesville Obstetrics & Gynecology (2021); Carnegie Mellon University (2012); Ithaca College (2016)

Faculty Researcher

18 h-index 33 pubs 1,404 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website

OverviewAI-generated summary

Young Hye Song's research focuses on tissue engineering and regenerative medicine, with a particular emphasis on developing advanced biomaterials and decellularization techniques for therapeutic applications. Song investigates the use of extracellular matrix (ECM) derived from decellularized tissues, such as peripheral nerves, as injectable scaffolds for nerve regeneration. This work involves studying the neuro-regenerative potential of cells, like adipose-derived stem cells, within engineered environments such as aligned collagen I hydrogels.

Further research extends to the versatility of mesenchymal stem cell-derived extracellular vesicles in tissue repair. Song also explores the role of nanomaterials, including graphene, carbon nanotubes, and nanocellulose, in creating scaffolds for tissue engineering applications. This research is supported by federal grants, including funding from the NIH/National Institute of Neurological Disorders and Stroke for developing in vitro test beds to study fibrotic scar after spinal cord injury, and from the NIH/National Cancer Institute for investigating metabolic rewiring in breast tumor innervation. Song also received NSF funding to expand the versatility of ECM hydrogels.

Song's scholarship is marked by a h-index of 18 and over 1,380 citations across 33 publications. Key collaborators include Emory Gregory, Younghye Song, Azemat Jamshidi‐Parsian, and Isabel Powers, with whom Song has co-authored multiple publications.

Metrics

h-index: 18
Publications: 33
Citations: 1,404

Selected Publications

Collagen I Hydrogel Microarchitecture Impact on MMP to TIMP Ratio and Inflammatory Pathways in Fibrosis Model (2026)

Journal of the Arkansas Academy of Science OpenAlex
Work-In-Progress: Bridging the Knowledge Gap- Integrating Design, 3D Modeling, Simulation, and Testing in a Junior-Level Biomaterials Course for Improved Student Outcomes and Employability (2025)

DOI OpenAlex
Pancreatic cancer extracellular vesicles stimulate Schwann cell activation and perineural invasion in vitro via IL-8/CCL2 (2025)

In vitro models 8 citations DOI OpenAlex
Abstract B026: Pancreatic tumor extracellular vesicles induce perineural invasion in vitro via IL- 8/CCL2 (2024)

Cancer Research 1 citation DOI OpenAlex
Investigation of neuro-regenerative therapeutic potential of nerve composite matrix hydrogels embedded with adipose-derived stem cells (2024)

Matrix Biology Plus 3 citations DOI OpenAlex
Development of Tissue-Engineered Model of Fibrotic Scarring after Spinal Cord Injury to Study Astrocyte Activation and Neurite Outgrowth In Vitro (2024)

ACS Biomaterials Science & Engineering 4 citations DOI OpenAlex
Development of Combinatorial Therapeutics for Spinal Cord Injury using Stem Cell Delivery (2024)

Journal of Visualized Experiments 4 citations DOI OpenAlex
Pancreatic Cancer Extracellular Vesicles Stimulate Schwann Cell Activation and Perineural Invasion in Vitro Via Il-8/Ccl2 (2024)

SSRN Electronic Journal DOI OpenAlex
Neuro-regenerative behavior of adipose-derived stem cells in aligned collagen I hydrogels (2023)

Materials Today Bio 15 citations DOI OpenAlex
Pancreatic Tumor-Derived Extracellular Vesicles Stimulate Schwann Cell Phenotype Indicative of Perineural Invasion via IL-8 Signaling (2023)

bioRxiv (Cold Spring Harbor Laboratory) 4 citations DOI OpenAlex
Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels (2023)

SSRN Electronic Journal DOI OpenAlex
Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels (2023)

bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
Nanomaterial-Based Scaffolds for Tissue Engineering Applications: A Review on Graphene, Carbon Nanotubes and Nanocellulose (2023)

Tissue Engineering and Regenerative Medicine 65 citations DOI OpenAlex
Versatility of mesenchymal stem cell-derived extracellular vesicles in tissue repair and regenerative applications (2022)

Biochimie 65 citations DOI OpenAlex
Apoptosis-Decellularized Peripheral Nerve Scaffold Allows Regeneration across Nerve Gap (2022)

Cells Tissues Organs 8 citations DOI OpenAlex