Emory Gregory

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Postdoctoral Fellow

University of Arkansas

Also affiliated: New York University (1984)

Postdoc Researcher

5 h-index 8 pubs 275 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website Research Group

OverviewAI-generated summary

Emory Gregory's research investigates the complex interplay between pancreatic cancer and the nervous system, particularly focusing on the role of extracellular vesicles and their signaling pathways in promoting perineural invasion. His work explores how tumor-derived extracellular vesicles stimulate Schwann cells, a type of glial cell that supports neurons, through signaling molecules like IL-8 and CCL2. This stimulation appears to induce a cellular phenotype consistent with perineural invasion, suggesting a mechanism by which cancer cells may leverage neural support structures to spread.

Gregory also examines the use of decellularized peripheral nerve extracellular matrix for creating hydrogels suitable for <i>in vitro</i> studies. This approach aims to provide a biomaterial scaffold that mimics the natural tissue environment, facilitating the study of cellular interactions and responses in a more physiologically relevant context. His research intersects cancer biology, neuroscience, and materials science, with a focus on understanding disease mechanisms and developing potential avenues for therapeutic intervention.

Metrics

h-index: 5
Publications: 8
Citations: 275

Selected Publications

Collagen I Hydrogel Microarchitecture Impact on MMP to TIMP Ratio and Inflammatory Pathways in Fibrosis Model (2026)

Journal of the Arkansas Academy of Science OpenAlex
Pancreatic cancer extracellular vesicles stimulate Schwann cell activation and perineural invasion in vitro via IL-8/CCL2 (2025)

In vitro models 8 citations DOI OpenAlex
Abstract B026: Pancreatic tumor extracellular vesicles induce perineural invasion in vitro via IL- 8/CCL2 (2024)

Cancer Research 1 citation DOI OpenAlex
Pancreatic Cancer Extracellular Vesicles Stimulate Schwann Cell Activation and Perineural Invasion in Vitro Via Il-8/Ccl2 (2024)

SSRN Electronic Journal DOI OpenAlex
Pancreatic Tumor-Derived Extracellular Vesicles Stimulate Schwann Cell Phenotype Indicative of Perineural Invasion via IL-8 Signaling (2023)

bioRxiv (Cold Spring Harbor Laboratory) 4 citations DOI OpenAlex
Peripheral Nerve Decellularization for <i>In Vitro</i> Extracellular Matrix Hydrogel Use: A Comparative Study (2022)

ACS Biomaterials Science & Engineering 14 citations DOI OpenAlex
Exploring the Role of Metabolites in Cancer and the Associated Nerve Crosstalk (2022)

Nutrients 18 citations DOI OpenAlex
The biology and engineered modeling strategies of cancer-nerve crosstalk (2020)

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 23 citations DOI OpenAlex