Match tier Confirmed
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-10-09

Young Hye Song

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI

Assistant Professor

Also affiliated: Cornell University (2013–2020); Konkuk University (2025–2026); University of Florida (2018–2022); Konkuk University Medical Center (2021–2026); Carnegie Mellon University (2012)

18 h-index 35 pubs 1,430 cited

  • Humans
  • Animals
  • Tissue Engineering
  • Extracellular Matrix
  • Hydrogels
  • Tissue Scaffolds
  • Rats
  • Collagen
  • Spinal Cord Injuries
  • Mesenchymal Stem Cells
  • Biocompatible Materials
  • Female
  • Stem Cells
  • Nerve Tissue
  • Apoptosis

Biography and Research Information

OverviewAI-generated summary

Young Hye Song's research focuses on tissue engineering and regenerative medicine, particularly in the context of spinal cord injury and cancer metastasis. Song's work investigates how the physical properties of the extracellular matrix, such as collagen microarchitecture, influence cellular behavior, including myofibroblast differentiation and cancer cell adhesion and migration. This research has been supported by federal grants from the NIH/National Neurological Disorders and Stroke and the NSF, totaling over $900,000, to develop in vitro test beds for studying spinal cord injury scarring and to explore the versatility of extracellular matrix hydrogels.

Additional research funded by the NIH/National Cancer Institute, for which Song serves as PI, examines the role of metabolic rewiring in breast tumor innervation. Song's publications also explore the use of biomaterials like PLGA/β-TCP/hydroxyapatite nanocomposites for bone defect repair in animal models and the application of decellularized tissues for in vitro disease modeling. With an h-index of 18 and over 1,400 citations across 34 publications, Song has established collaborations with researchers at the University of Arkansas at Fayetteville and the University of Arkansas for Medical Sciences.

Metrics

  • h-index: 18
  • Publications: 35
  • Citations: 1,430

Positions

  • Assistant Professor 2019–present
    University of Arkansas Biomedical Engineering ORCID
  • Postdoctoral Research Associate 2016–2019
    University of Florida Biomedical Engineering ORCID

Selected Publications

  • Enhancing the Scalable Manufacturing of Human Mesenchymal Stromal Cells in Dynamic Culture Using Bioactive Heparin/Collagen Layer‐by‐Layer Coated Microcarriers (2026)
    Biotechnology Journal DOI OpenAlex
  • Collagen I Hydrogel Microarchitecture Impact on MMP to TIMP Ratio and Inflammatory Pathways in Fibrosis Model (2026)
    Journal of the Arkansas Academy of Science OpenAlex
  • Work-In-Progress: Bridging the Knowledge Gap- Integrating Design, 3D Modeling, Simulation, and Testing in a Junior-Level Biomaterials Course for Improved Student Outcomes and Employability (2025)
  • Pancreatic cancer extracellular vesicles stimulate Schwann cell activation and perineural invasion in vitro via IL-8/CCL2 (2025)
    In vitro models 9 citations DOI OpenAlex
  • Abstract B026: Pancreatic tumor extracellular vesicles induce perineural invasion in vitro via IL- 8/CCL2 (2024)
    Cancer Research 1 citation DOI OpenAlex
  • Investigation of neuro-regenerative therapeutic potential of nerve composite matrix hydrogels embedded with adipose-derived stem cells (2024)
    Matrix Biology Plus 3 citations DOI OpenAlex
  • Development of Tissue-Engineered Model of Fibrotic Scarring after Spinal Cord Injury to Study Astrocyte Activation and Neurite Outgrowth In Vitro (2024)
    ACS Biomaterials Science & Engineering 4 citations DOI OpenAlex
  • Development of Combinatorial Therapeutics for Spinal Cord Injury using Stem Cell Delivery (2024)
    Journal of Visualized Experiments 4 citations DOI OpenAlex
  • Pancreatic Cancer Extracellular Vesicles Stimulate Schwann Cell Activation and Perineural Invasion in Vitro Via Il-8/Ccl2 (2024)
    SSRN Electronic Journal DOI OpenAlex
  • Neuro-regenerative behavior of adipose-derived stem cells in aligned collagen I hydrogels (2023)
    Materials Today Bio 15 citations DOI OpenAlex
  • Pancreatic Tumor-Derived Extracellular Vesicles Stimulate Schwann Cell Phenotype Indicative of Perineural Invasion via IL-8 Signaling (2023)
    bioRxiv (Cold Spring Harbor Laboratory) 4 citations DOI OpenAlex
  • Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels (2023)
    SSRN Electronic Journal DOI OpenAlex
  • Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels (2023)
    bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
  • Nanomaterial-Based Scaffolds for Tissue Engineering Applications: A Review on Graphene, Carbon Nanotubes and Nanocellulose (2023)
    Tissue Engineering and Regenerative Medicine 69 citations DOI OpenAlex
  • Versatility of mesenchymal stem cell-derived extracellular vesicles in tissue repair and regenerative applications (2022)
    Biochimie 68 citations DOI OpenAlex

View all publications on OpenAlex →

Federal Grants 3 $1,417,365 total

NIH Contact PI May 2024 - Apr 2029

Investigating the role of metabolic rewiring in breast tumor innervation

National Cancer Institute $497,581 R37
NIH Contact PI Apr 2021 - Mar 2025

Bioengineering in vitro test beds to study fibrotic scar after spinal cord injury

National Institute of Neurological Disorders and Stroke $429,784 R15
NSF PI Aug 2025 - Jul 2028

Towards expanding versatility of extracellular matrix hydrogels

Engineering of Biomed Systems $490,000

Collaboration Network

66 Collaborators 12 Institutions 3 Countries

Top Collaborators

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