Young Hye Song
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Assistant Professor
Also affiliated: Cornell University (2013–2020); Konkuk University (2025–2026); University of Florida (2018–2022); Konkuk University Medical Center (2021–2026); Carnegie Mellon University (2012)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Young Hye Song's research focuses on tissue engineering and regenerative medicine, particularly in the context of spinal cord injury and cancer metastasis. Song's work investigates how the physical properties of the extracellular matrix, such as collagen microarchitecture, influence cellular behavior, including myofibroblast differentiation and cancer cell adhesion and migration. This research has been supported by federal grants from the NIH/National Neurological Disorders and Stroke and the NSF, totaling over $900,000, to develop in vitro test beds for studying spinal cord injury scarring and to explore the versatility of extracellular matrix hydrogels.
Additional research funded by the NIH/National Cancer Institute, for which Song serves as PI, examines the role of metabolic rewiring in breast tumor innervation. Song's publications also explore the use of biomaterials like PLGA/β-TCP/hydroxyapatite nanocomposites for bone defect repair in animal models and the application of decellularized tissues for in vitro disease modeling. With an h-index of 18 and over 1,400 citations across 34 publications, Song has established collaborations with researchers at the University of Arkansas at Fayetteville and the University of Arkansas for Medical Sciences.
Metrics
- h-index: 18
- Publications: 35
- Citations: 1,430
Positions
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Assistant Professor 2019–presentUniversity of Arkansas Biomedical Engineering ORCID
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Postdoctoral Research Associate 2016–2019University of Florida Biomedical Engineering ORCID
Selected Publications
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Enhancing the Scalable Manufacturing of Human Mesenchymal Stromal Cells in Dynamic Culture Using Bioactive Heparin/Collagen Layer‐by‐Layer Coated Microcarriers (2026)
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Collagen I Hydrogel Microarchitecture Impact on MMP to TIMP Ratio and Inflammatory Pathways in Fibrosis Model (2026)Journal of the Arkansas Academy of Science OpenAlex
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Work-In-Progress: Bridging the Knowledge Gap- Integrating Design, 3D Modeling, Simulation, and Testing in a Junior-Level Biomaterials Course for Improved Student Outcomes and Employability (2025)
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Pancreatic cancer extracellular vesicles stimulate Schwann cell activation and perineural invasion in vitro via IL-8/CCL2 (2025)
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Abstract B026: Pancreatic tumor extracellular vesicles induce perineural invasion in vitro via IL- 8/CCL2 (2024)
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Investigation of neuro-regenerative therapeutic potential of nerve composite matrix hydrogels embedded with adipose-derived stem cells (2024)
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Development of Tissue-Engineered Model of Fibrotic Scarring after Spinal Cord Injury to Study Astrocyte Activation and Neurite Outgrowth In Vitro (2024)
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Development of Combinatorial Therapeutics for Spinal Cord Injury using Stem Cell Delivery (2024)
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Pancreatic Cancer Extracellular Vesicles Stimulate Schwann Cell Activation and Perineural Invasion in Vitro Via Il-8/Ccl2 (2024)
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Neuro-regenerative behavior of adipose-derived stem cells in aligned collagen I hydrogels (2023)
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Pancreatic Tumor-Derived Extracellular Vesicles Stimulate Schwann Cell Phenotype Indicative of Perineural Invasion via IL-8 Signaling (2023)
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Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels (2023)
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Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels (2023)
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Nanomaterial-Based Scaffolds for Tissue Engineering Applications: A Review on Graphene, Carbon Nanotubes and Nanocellulose (2023)
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Versatility of mesenchymal stem cell-derived extracellular vesicles in tissue repair and regenerative applications (2022)
Federal Grants 3 $1,417,365 total
Investigating the role of metabolic rewiring in breast tumor innervation
Bioengineering in vitro test beds to study fibrotic scar after spinal cord injury
Towards expanding versatility of extracellular matrix hydrogels
Collaboration Network
Top Collaborators
- Decellularized tissues as platforms for in vitro modeling of healthy and diseased tissues
- Novel Sodium Deoxycholate-Based Chemical Decellularization Method for Peripheral Nerve
- Development of novel apoptosis-assisted lung tissue decellularization methods
- Oligonucleotide-functionalized hydrogels for sustained release of small molecule (aptamer) therapeutics
- Decellularized peripheral nerve as an injectable delivery vehicle for neural applications
Showing 5 of 7 shared publications
- The biology and engineered modeling strategies of cancer-nerve crosstalk
- Exploring the Role of Metabolites in Cancer and the Associated Nerve Crosstalk
- Peripheral Nerve Decellularization for In Vitro Extracellular Matrix Hydrogel Use: A Comparative Study
- Pancreatic cancer extracellular vesicles stimulate Schwann cell activation and perineural invasion in vitro via IL-8/CCL2
- Pancreatic Tumor-Derived Extracellular Vesicles Stimulate Schwann Cell Phenotype Indicative of Perineural Invasion via IL-8 Signaling
Showing 5 of 7 shared publications
- Neuro-regenerative behavior of adipose-derived stem cells in aligned collagen I hydrogels
- Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels
- Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels
- Work-In-Progress: Bridging the Knowledge Gap- Integrating Design, 3D Modeling, Simulation, and Testing in a Junior-Level Biomaterials Course for Improved Student Outcomes and Employability
- Collagen I Hydrogel Microarchitecture Impact on MMP to TIMP Ratio and Inflammatory Pathways in Fibrosis Model
- Novel Sodium Deoxycholate-Based Chemical Decellularization Method for Peripheral Nerve
- Development of novel apoptosis-assisted lung tissue decellularization methods
- Decellularized peripheral nerve as an injectable delivery vehicle for neural applications
- Development of novel apoptosis-assisted lung tissue decellularization methods
- The biology and engineered modeling strategies of cancer-nerve crosstalk
- Neuro-regenerative behavior of adipose-derived stem cells in aligned collagen I hydrogels
- Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels
- Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels
- Nanomaterial-Based Scaffolds for Tissue Engineering Applications: A Review on Graphene, Carbon Nanotubes and Nanocellulose
- Neuro-regenerative behavior of adipose-derived stem cells in aligned collagen I hydrogels
- Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels
- Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels
- Pancreatic cancer extracellular vesicles stimulate Schwann cell activation and perineural invasion in vitro via IL-8/CCL2
- Pancreatic Tumor-Derived Extracellular Vesicles Stimulate Schwann Cell Phenotype Indicative of Perineural Invasion via IL-8 Signaling
- Abstract B026: Pancreatic tumor extracellular vesicles induce perineural invasion in vitro via IL- 8/CCL2
- Pancreatic Cancer Extracellular Vesicles Stimulate Schwann Cell Activation and Perineural Invasion in Vitro Via Il-8/Ccl2
- Pancreatic cancer extracellular vesicles stimulate Schwann cell activation and perineural invasion in vitro via IL-8/CCL2
- Pancreatic Tumor-Derived Extracellular Vesicles Stimulate Schwann Cell Phenotype Indicative of Perineural Invasion via IL-8 Signaling
- Abstract B026: Pancreatic tumor extracellular vesicles induce perineural invasion in vitro via IL- 8/CCL2
- Pancreatic Cancer Extracellular Vesicles Stimulate Schwann Cell Activation and Perineural Invasion in Vitro Via Il-8/Ccl2
- Pancreatic cancer extracellular vesicles stimulate Schwann cell activation and perineural invasion in vitro via IL-8/CCL2
- Pancreatic Tumor-Derived Extracellular Vesicles Stimulate Schwann Cell Phenotype Indicative of Perineural Invasion via IL-8 Signaling
- Abstract B026: Pancreatic tumor extracellular vesicles induce perineural invasion in vitro via IL- 8/CCL2
- Pancreatic Cancer Extracellular Vesicles Stimulate Schwann Cell Activation and Perineural Invasion in Vitro Via Il-8/Ccl2
- Development of Combinatorial Therapeutics for Spinal Cord Injury using Stem Cell Delivery
- Development of Tissue-Engineered Model of Fibrotic Scarring after Spinal Cord Injury to Study Astrocyte Activation and Neurite Outgrowth In Vitro
- Investigation of neuro-regenerative therapeutic potential of nerve composite matrix hydrogels embedded with adipose-derived stem cells
- Abstract B026: Pancreatic tumor extracellular vesicles induce perineural invasion in vitro via IL- 8/CCL2
- Decellularized tissues as platforms for in vitro modeling of healthy and diseased tissues
- Novel Sodium Deoxycholate-Based Chemical Decellularization Method for Peripheral Nerve
- Decellularized peripheral nerve as an injectable delivery vehicle for neural applications
- Novel Sodium Deoxycholate-Based Chemical Decellularization Method for Peripheral Nerve
- Oligonucleotide-functionalized hydrogels for sustained release of small molecule (aptamer) therapeutics
- Apoptosis-Decellularized Peripheral Nerve Scaffold Allows Regeneration across Nerve Gap
- Development of novel apoptosis-assisted lung tissue decellularization methods
- Apoptosis-Decellularized Peripheral Nerve Scaffold Allows Regeneration across Nerve Gap
- Development of novel apoptosis-assisted lung tissue decellularization methods
- The biology and engineered modeling strategies of cancer-nerve crosstalk
- Peripheral Nerve Decellularization for In Vitro Extracellular Matrix Hydrogel Use: A Comparative Study
- Abstract B026: Pancreatic tumor extracellular vesicles induce perineural invasion in vitro via IL- 8/CCL2
- Peripheral Nerve Decellularization for In Vitro Extracellular Matrix Hydrogel Use: A Comparative Study
- Development of Tissue-Engineered Model of Fibrotic Scarring after Spinal Cord Injury to Study Astrocyte Activation and Neurite Outgrowth In Vitro
- Work-In-Progress: Bridging the Knowledge Gap- Integrating Design, 3D Modeling, Simulation, and Testing in a Junior-Level Biomaterials Course for Improved Student Outcomes and Employability
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