Zheng‐Yu Wang

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Research Associate Professor

UAMS

24 h-index 77 pubs 2,317 cited

Research Areas

Biomedical Subjects

Links

ORCID

OverviewAI-generated summary

Zheng‐Yu Wang's research focuses on xenotransplantation, specifically investigating methods to reduce immunological barriers between species. His work has involved the genetic modification of pigs to create models for transplantation studies. Publications detail the generation of pigs deficient in specific carbohydrate antigens, such as N-glycolylneuraminic acid and galactose α-1,3-galactose, which are known targets for immune rejection in xenotransplantation.

Further research includes the development of genetically modified pigs lacking Class I MHC, a key component of the immune system. Wang has also explored the potential of erythrocytes from genetically modified pigs for xenotransfusion applications. His research utilizes techniques such as CRISPR-Cas9 for gene editing and multiplexed single-guide RNA for efficient genetic modification. Collaborations within the University of Arkansas for Medical Sciences contribute to his research network.

Beyond xenotransplantation, Wang's publications also touch on other areas of molecular biology, including the role of NSUN2 as a glucose sensor in cancer and the regulation of cytokine gene expression in immune cells. His scholarship metrics include an h-index of 24, with 77 total publications and over 2,300 citations.

Metrics

h-index: 24
Publications: 77
Citations: 2,317

Positions

Research Associate Professor 2020–present

University of Miami Miller School of Medicine Palm Beach Regional Campus Miami Transplant Institute, Department of Surgery ORCID
Research Associate Professor

University of Arkansas for Medical Sciences ORCID
Assistant Professor 2016–2020

The University of Alabama at Birmingham School of Medicine Department of Surgery ORCID
Research Assistant Professor 2010–2016

Indiana University School of Medicine Department of Surgery ORCID
Physician/Attending 1988–1997

Liaoning Health Industry Group Fushun General Hospital Neurology ORCID

Selected Publications

CD36-mediated endocytosis of proteolysis-targeting chimeras (2025)

Cell 58 citations DOI OpenAlex
NSUN2 is a glucose sensor suppressing cGAS/STING to maintain tumorigenesis and immunotherapy resistance (2023)

Cell Metabolism 211 citations DOI OpenAlex