Drug Development

Research in drug development focuses on the discovery, design, and testing of new therapeutic agents. Investigations explore the pharmacological effects and toxicity of potential drugs, employing methods such as microphysiological systems and cellular assays to model human responses. This area encompasses the identification of biomarkers for drug efficacy and toxicity, the examination of phytochemicals for therapeutic and antioxidant activities, and the development of novel treatments for diseases like cancer. Specific interests include understanding and mitigating drug-induced organ damage, such as hepatotoxicity, and advancing diagnostic and treatment strategies for conditions like lung cancer.

This work holds significant relevance for Arkansas by addressing public health needs and potentially fostering economic growth in the biotechnology and pharmaceutical sectors. Research into cancer treatment and pharmacology, for instance, directly impacts the health of Arkansans, where cancer incidence and mortality rates are areas of public health concern. Furthermore, the exploration of natural products, such as phytochemicals found in Arkansas's diverse flora, offers opportunities for discovering novel compounds with medicinal properties, potentially creating new avenues for agricultural and industrial development within the state.

This field draws upon expertise in pharmacology, toxicology, chemistry, and biology. Investigations are conducted across multiple institutions, fostering collaboration and a broad range of scientific inquiry. The research is closely linked to studies in drug discovery, toxicity mechanisms, and the development of advanced testing platforms.