Match tier Listed
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-15

Shivangi Shrimali

Researcher

Also affiliated: United States Food and Drug Administration (2025–2026)

Unknown Researcher

3 h-index 6 pubs 32 cited

  • Animals
  • Drug Evaluation, Preclinical
  • Humans
  • Chemical and Drug Induced Liver Injury
  • Microphysiological Systems
  • Pharmaceutical Preparations
  • Disease Models, Animal
  • Drug Development
  • Tissue Distribution
  • Toxicity Tests

Biography and Research Information

OverviewAI-generated summary

Shivangi Shrimali's research focuses on developing and evaluating new methodologies for drug safety assessment, particularly in the context of drug-induced liver injury (DILI) and radioprotection. Her work investigates the use of microphysiological systems, also known as new approach methodologies (NAMs), as alternatives to traditional animal testing for evaluating drug absorption, distribution, metabolism, excretion, and toxicity. Shrimali has also explored the potential of tocotrienol analogues, such as tocoflexol, as radioprotective agents, examining their antioxidant and signaling mechanisms. Her research also includes investigating the effects of specific substances, like titanium dioxide, on cellular processes, such as microRNA expression. Shrimali collaborates with researchers from the University of Arkansas for Medical Sciences and the University of Arkansas at Fayetteville.

Metrics

  • h-index: 3
  • Publications: 6
  • Citations: 32

Selected Publications

  • Integrating in vitro and in silico NAMs for enhanced prediction of drug-induced liver injury (2026)
    Drug Discovery Today DOI OpenAlex
  • Exposure to a Titanium Dioxide Product Alters MicroRNA Expression in Human Cells (2026)
    Toxics DOI OpenAlex
  • Microphysiological systems as an emerging in vitro approach for the evaluation of drug absorption, distribution, metabolism, and excretion and toxicity (2025)
    Drug Metabolism and Disposition 8 citations DOI OpenAlex
  • New approach methodologies (NAMs) for drug-induced liver injury (DILI): Where are we now? (2025)
    Drug Discovery Today 10 citations DOI OpenAlex
  • Tocotrienols Provide Radioprotection to Multiple Organ Systems through Complementary Mechanisms of Antioxidant and Signaling Effects (2023)
    Antioxidants 11 citations DOI OpenAlex
  • 466 Development of a novel tocotrienol analogue, tocoflexol, as a radiomitigator (2023)
    Journal of Clinical and Translational Science DOI OpenAlex

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Collaboration Network

23 Collaborators 4 Institutions 1 Country

Top Collaborators

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