Marta Pogribna
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Also affiliated: Louisiana State University (1999); Arkansas Children's Hospital (1999); United States Food and Drug Administration (2013–2023); Saginaw Valley State University (1999); Biochemical Society (2012); University of Tennessee at Knoxville (2006)
Formerly Arkansas Affiliated with NCTR, UAMS through 2024.
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Marta Pogribna investigates the epigenetic effects of nanomaterials, with a particular focus on titanium dioxide nanoparticles. Her research examines how exposure to these substances alters DNA methylation and histone modifications in human cell lines and animal models.
Her work has resulted in 31 publications, which have garnered over 4,000 citations, and she has an h-index of 24. Pogribna is recognized as a highly cited researcher. She has collaborated on multiple publications with researchers at the National Center for Toxicological Research, including George Hammons, Beverly Lyn-Cook, Beverly Word, and Carlos M. Wells.
Metrics
- h-index: 24
- Publications: 31
- Citations: 4,113
Selected Publications
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Exposure to a Titanium Dioxide Product Alters MicroRNA Expression in Human Cells (2026)
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Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells (2024)
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Epigenotoxicity of Titanium Dioxide Nanoparticles (2023)
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Effect of titanium dioxide nanoparticles on histone modifications and histone modifying enzymes expression in human cell lines (2022)
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Epigenetic Effects of Nanomaterials and Nanoparticles (2021)
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Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines (2020)
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Epigenetically mediated inhibition of S‐adenosylhomocysteine hydrolase and the associated dysregulation of 1‐carbon metabolism in nonalcoholic steatohepatitis and hepatocellular carcinoma (2017)
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In vitro analysis of factors influencingCYP1A2expression as potential determinants of interindividual variation (2017)
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Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein (2016)
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Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism (2014)
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Strain‐dependent dysregulation of one‐carbon metabolism in male mice is associated with choline‐ and folate‐deficient diet‐induced liver injury (2013)
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Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents (2013)
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Modifying metabolically sensitive histone marks by inhibiting glutamine metabolism affects gene expression and alters cancer cell phenotype (2012)
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Effect of Aloe vera whole leaf extract on short chain fatty acids production by Bacteroides fragilis, Bifidobacterium infantis and Eubacterium limosum (2008)
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Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats (2006)
Collaboration Network
Top Collaborators
- Increase in Plasma Homocysteine Associated with Parallel Increases in Plasma S-Adenosylhomocysteine and Lymphocyte DNA Hypomethylation
- Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome
- Elevation in S-Adenosylhomocysteine and DNA Hypomethylation: Potential Epigenetic Mechanism for Homocysteine-Related Pathology
- Homocysteine Metabolism in Children with Down Syndrome: In Vitro Modulation
- Measurement of Plasma and Intracellular S-Adenosylmethionine and S-Adenosylhomocysteine Utilizing Coulometric Electrochemical Detection: Alterations with Plasma Homocysteine and Pyridoxal 5′-Phosphate Concentrations
Showing 5 of 17 shared publications
- Increase in Plasma Homocysteine Associated with Parallel Increases in Plasma S-Adenosylhomocysteine and Lymphocyte DNA Hypomethylation
- Elevation in S-Adenosylhomocysteine and DNA Hypomethylation: Potential Epigenetic Mechanism for Homocysteine-Related Pathology
- Homocysteine Metabolism in Children with Down Syndrome: In Vitro Modulation
- Measurement of Plasma and Intracellular S-Adenosylmethionine and S-Adenosylhomocysteine Utilizing Coulometric Electrochemical Detection: Alterations with Plasma Homocysteine and Pyridoxal 5′-Phosphate Concentrations
- Mechanisms of DNA Damage, DNA Hypomethylation, and Tumor Progression in the Folate/Methyl-Deficient Rat Model of Hepatocarcinogenesis
Showing 5 of 13 shared publications
- Increase in Plasma Homocysteine Associated with Parallel Increases in Plasma S-Adenosylhomocysteine and Lymphocyte DNA Hypomethylation
- Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome
- Elevation in S-Adenosylhomocysteine and DNA Hypomethylation: Potential Epigenetic Mechanism for Homocysteine-Related Pathology
- Homocysteine Metabolism in Children with Down Syndrome: In Vitro Modulation
- Measurement of Plasma and Intracellular S-Adenosylmethionine and S-Adenosylhomocysteine Utilizing Coulometric Electrochemical Detection: Alterations with Plasma Homocysteine and Pyridoxal 5′-Phosphate Concentrations
Showing 5 of 11 shared publications
- Irreversible global DNA hypomethylation as a key step in hepatocarcinogenesis induced by dietary methyl deficiency
- Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats
- Modifying metabolically sensitive histone marks by inhibiting glutamine metabolism affects gene expression and alters cancer cell phenotype
- Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents
- Strain‐dependent dysregulation of one‐carbon metabolism in male mice is associated with choline‐ and folate‐deficient diet‐induced liver injury
Showing 5 of 8 shared publications
- Epigenetic Effects of Nanomaterials and Nanoparticles
- Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines
- In vitro analysis of factors influencingCYP1A2expression as potential determinants of interindividual variation
- Effect of titanium dioxide nanoparticles on histone modifications and histone modifying enzymes expression in human cell lines
- Epigenotoxicity of Titanium Dioxide Nanoparticles
Showing 5 of 7 shared publications
- Modifying metabolically sensitive histone marks by inhibiting glutamine metabolism affects gene expression and alters cancer cell phenotype
- Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents
- Strain‐dependent dysregulation of one‐carbon metabolism in male mice is associated with choline‐ and folate‐deficient diet‐induced liver injury
- Epigenetically mediated inhibition of S‐adenosylhomocysteine hydrolase and the associated dysregulation of 1‐carbon metabolism in nonalcoholic steatohepatitis and hepatocellular carcinoma
- Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism
Showing 5 of 6 shared publications
- Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome
- Polymorphisms in Genes Involved in Folate Metabolism as Maternal Risk Factors for Down Syndrome
- Homocysteine Metabolism in Children with Down Syndrome: In Vitro Modulation
- Measurement of Plasma and Intracellular S-Adenosylmethionine and S-Adenosylhomocysteine Utilizing Coulometric Electrochemical Detection: Alterations with Plasma Homocysteine and Pyridoxal 5′-Phosphate Concentrations
- Abnormal folate metabolism and genetic polymorphism of the folate pathway in a child with Down syndrome and neural tube defect
- Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines
- In vitro analysis of factors influencingCYP1A2expression as potential determinants of interindividual variation
- Effect of titanium dioxide nanoparticles on histone modifications and histone modifying enzymes expression in human cell lines
- Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells
- Exposure to a Titanium Dioxide Product Alters MicroRNA Expression in Human Cells
- Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines
- In vitro analysis of factors influencingCYP1A2expression as potential determinants of interindividual variation
- Effect of titanium dioxide nanoparticles on histone modifications and histone modifying enzymes expression in human cell lines
- Epigenotoxicity of Titanium Dioxide Nanoparticles
- Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells
- Mechanisms of DNA Damage, DNA Hypomethylation, and Tumor Progression in the Folate/Methyl-Deficient Rat Model of Hepatocarcinogenesis
- Uracil misincorporation, DNA strand breaks, and gene amplification are associated with tumorigenic cell transformation in folate deficient/repleted Chinese hamster ovary cells
- Characterization of cellular response to silicone implants in rats: implications for foreign-body carcinogenesis
- Mechanisms of DNA Damage, DNA Hypomethylation, and Tumor Progression in the Folate/Methyl-Deficient Rat Model of Hepatocarcinogenesis
- Thimerosal Neurotoxicity is Associated with Glutathione Depletion: Protection with Glutathione Precursors
- Genomic hypomethylation is specific for preneoplastic liver in folate/methyl deficient rats and does not occur in non-target tissues
- Increase in Plasma Homocysteine Associated with Parallel Increases in Plasma S-Adenosylhomocysteine and Lymphocyte DNA Hypomethylation
- Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome
- Polymorphisms in Genes Involved in Folate Metabolism as Maternal Risk Factors for Down Syndrome
- Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents
- Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism
- Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein
- Irreversible global DNA hypomethylation as a key step in hepatocarcinogenesis induced by dietary methyl deficiency
- Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats
- Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism
- Characterization of cellular response to silicone implants in rats: implications for foreign-body carcinogenesis
- Strain‐dependent dysregulation of one‐carbon metabolism in male mice is associated with choline‐ and folate‐deficient diet‐induced liver injury
- Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism
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