Beverly Word

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Researcher

NCTR

Also affiliated: United States Food and Drug Administration (2016–2022); Missouri Department of Agriculture (2018); Jefferson Community and Technical College (2014); Office of Multidisciplinary Activities (2013); Western University of Health Sciences (2008)

Faculty Researcher

19 h-index 63 pubs 917 cited

Research Areas

Biomedical Subjects

OverviewAI-generated summary

Beverly Word's research focuses on the molecular mechanisms underlying cancer development and the pharmacological effects of potential therapeutic agents. Her work investigates how environmental factors, such as nanoparticles and chemical exposures, can alter gene expression and epigenetic modifications, including DNA methylation and histone modifications, in human cell lines. She has explored the anti-cancer effects of histone deacetylase (HDAC) inhibitors, specifically vorinostat, on pancreatic and triple-negative breast cancer models, including those cultured in three-dimensional environments and organoids. Her research has also identified specific gene expression profiles associated with African American pancreatic cancer tumors. Word holds an h-index of 19 with 63 total publications and 907 citations. She has collaborated extensively with researchers at the National Center for Toxicological Research, including Beverly Lyn‐Cook, George Hammons, Fatemeh Nouri Emamzaden, and Marta Pogribna.

Metrics

h-index: 19
Publications: 63
Citations: 917

Selected Publications

Exposure to a Titanium Dioxide Product Alters MicroRNA Expression in Human Cells (2026)

Toxics DOI OpenAlex
Abstract C054: Pharmacogenomics evaluation of histone deacetylase inhibitors on the treatment of triple-negative breast cancer subtypes (2025)

Cancer Epidemiology Biomarkers & Prevention DOI OpenAlex
Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells (2024)

Nanomaterials 2 citations DOI OpenAlex
Abstract 4253: High expression of specific gene profiles in organoids from African American pancreatic cancer tumors (2024)

Cancer Research DOI OpenAlex
Abstract 6251: High expression level of GSK3β in basal triple negative breast cancer: Effects of the HDAC inhibitor, vorinostat (2023)

Cancer Research DOI OpenAlex
Effect of titanium dioxide nanoparticles on histone modifications and histone modifying enzymes expression in human cell lines (2022)

Nanotoxicology 9 citations DOI OpenAlex
Abstract 1631: Anti-cancer effects of vorinostat on 3D cultured pancreatic cancer cells (2022)

Cancer Research 1 citation DOI OpenAlex
Abstract 995: Alpelisib and vorinostat modulate critical genes in basal-2 triple negative breast cancer cells and inhibit cell growth and invasion (2021)

Cancer Research DOI OpenAlex
Abstract B125: Molecular profiling basal 2 subtypes of triple-negative breast cancer cells and their response to histone deacetylase inhibitor (2020)

Cancer Epidemiology Biomarkers & Prevention DOI OpenAlex
Abstract PO-218: Molecular profiling of basal 2 subtypes of triple negative breast cancer cells and their response to a histone deacetylase inhibitor (2020)

Cancer Epidemiology Biomarkers & Prevention DOI OpenAlex
Abstract C109: Modulation of HDAC activity in subtypes of triple-negative breast cancer: Effects of vorinostat on HDAC 7 expression and cancer stem cells progression (2020)

Cancer Epidemiology Biomarkers & Prevention DOI OpenAlex
Modulation of Estrogen α and Progesterone Receptors in Triple Negative Breast Cancer Cell Lines: The Effects of Vorinostat and Indole-3-Carbinol In Vitro (2020)

Anticancer Research 24 citations DOI OpenAlex
Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines (2020)

Nanotoxicology 94 citations DOI OpenAlex
Abstract 5196: Vorinostat exhibits anticancer effects through modulation of nuclear receptors and tumor suppressor genes in sub-types of triple negative breast cancer cells (2019)

Molecular and Cellular Biology / Genetics DOI OpenAlex
Epigenome-wide association study of peripheral blood mononuclear cells in systemic lupus erythematosus: Identifying DNA methylation signatures associated with interferon-related genes based on ethnicity and SLEDAI (2018)

Journal of Autoimmunity 88 citations DOI OpenAlex