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Presence
Formerly Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-06
G
George Hammons
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Also affiliated: United States Food and Drug Administration (1985–2023); Los Alamos National Laboratory (1972); East Carolina University (2014); Texas A&M University (2026)
Formerly Arkansas Affiliated with UA Little Rock, Philander Smith University, NCTR, UAMS through 2024.
24 h-index
74 pubs
2,057 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
George Hammons' research focuses on the genotoxicity and epigenetic effects of nanomaterials, particularly titanium dioxide nanoparticles, in human cells. His work investigates how exposure to these substances can alter DNA methylation and microRNA expression. Hammons has also explored the anti-cancer effects of vorinostat on pancreatic cancer cells and has investigated gene expression profiles in pancreatic tumors from African American patients.
His research network includes several collaborators from the National Center for Toxicological Research, including Beverly Lyn‐Cook, Beverly Word, Marta Pogribna, and Fatemeh Nouri Emamzaden, with whom he has co-authored multiple publications. Hammons' work contributes to the understanding of potential health impacts associated with nanomaterial exposure and advancements in cancer research.
Hammons has published 74 papers, accumulating over 2,034 citations and an h-index of 24, indicating a significant body of scholarly work in his research areas.
Metrics
- h-index: 24
- Publications: 74
- Citations: 2,057
Selected Publications
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Exposure to a Titanium Dioxide Product Alters MicroRNA Expression in Human Cells (2026)
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Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells (2024)
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Abstract 4253: High expression of specific gene profiles in organoids from African American pancreatic cancer tumors (2024)
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Epigenotoxicity of Titanium Dioxide Nanoparticles (2023)
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Abstract 6251: High expression level of GSK3β in basal triple negative breast cancer: Effects of the HDAC inhibitor, vorinostat (2023)
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Effect of titanium dioxide nanoparticles on histone modifications and histone modifying enzymes expression in human cell lines (2022)
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Abstract 1631: Anti-cancer effects of vorinostat on 3D cultured pancreatic cancer cells (2022)
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Abstract 995: Alpelisib and vorinostat modulate critical genes in basal-2 triple negative breast cancer cells and inhibit cell growth and invasion (2021)
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Epigenetic Effects of Nanomaterials and Nanoparticles (2021)
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Abstract B125: Molecular profiling basal 2 subtypes of triple-negative breast cancer cells and their response to histone deacetylase inhibitor (2020)
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Abstract PO-218: Molecular profiling of basal 2 subtypes of triple negative breast cancer cells and their response to a histone deacetylase inhibitor (2020)
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Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines (2020)
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Proteomics Profiling of Pancreatic Cancer and Pancreatitis for Biomarkers Discovery (2018)
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Abstract B19: The role of ABCB1 genotypes and targeting cancer stem cells in pancreatic cancer: Effects of metformin and dietary agents (2017)
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In vitro analysis of factors influencingCYP1A2expression as potential determinants of interindividual variation (2017)
Collaboration Network
Top Collaborators
Beverly Lyn‐Cook
National Center for Toxicological Research
42 shared publications
In database
- Human CYP1B1 Leu432Val gene polymorphism: ethnic distribution in African-Americans, Caucasians and Chinese; oestradiol hydroxylase activity; and distribution in prostate cancer cases and controls
- Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype
- Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines
- Increased expression of heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNP) in pancreatic tissue from smokers and pancreatic tumor cells
- Expression of drug transporters in human kidney: impact of sex, age, and ethnicity
Showing 5 of 42 shared publications
Beverly Word
National Center for Toxicological Research
33 shared publications
In database
- Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines
- Expression of drug transporters in human kidney: impact of sex, age, and ethnicity
- Age and gender affect DNMT3a and DNMT3b expression in human liver
- Increased levels of NAD(P)H: quinone oxidoreductase 1 (NQO1) in pancreatic tissues from smokers and pancreatic adenocarcinomas: A potential biomarker of early damage in the pancreas
- Food contaminant acrylamide increases expression of Cox-2 and nitric oxide synthase in breast epithelial cells
Showing 5 of 33 shared publications
Fred F. Kadlubar
National Center for Toxicological Research (US)
9 shared publications
- Human CYP1B1 Leu432Val gene polymorphism: ethnic distribution in African-Americans, Caucasians and Chinese; oestradiol hydroxylase activity; and distribution in prostate cancer cases and controls
- Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype
- Specific site methylation in the 5′-flanking region of CYP1A2
- CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk.
- Effects of chemoprotective agents on the metabolic activation of the carcinogenic arylamines PhIP and 4‐aminobiphenyl in human and rat liver microsomes
Showing 5 of 9 shared publications
Lascelles E. Lyn‐Cook
National Center for Toxicological Research
8 shared publications
In database
- Food contaminant acrylamide increases expression of Cox-2 and nitric oxide synthase in breast epithelial cells
- Cigarette Smoke Condensate Induces Differential Expression and Promoter Methylation Profiles of Critical Genes Involved in Lung Cancer in NL-20 Lung Cells In Vitro
- Effect of cigarette smoke condensate on gene promoter methylation in human lung cells
- In vitro analysis of factors influencingCYP1A2expression as potential determinants of interindividual variation
- Cigarette smoke condensate and individual constituents modulate DNA methyltransferase expression in human liver cells
Showing 5 of 8 shared publications
Marta Pogribna
National Center for Toxicological Research
7 shared publications
In database
- Epigenetic Effects of Nanomaterials and Nanoparticles
- Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines
- In vitro analysis of factors influencingCYP1A2expression as potential determinants of interindividual variation
- Effect of titanium dioxide nanoparticles on histone modifications and histone modifying enzymes expression in human cell lines
- Epigenotoxicity of Titanium Dioxide Nanoparticles
Showing 5 of 7 shared publications
Ernice Blann
National Center for Toxicological Research (US)
4 shared publications
- Specific site methylation in the 5′-flanking region of CYP1A2
- Increased expression of hepatic DNA methyltransferase in smokers
- The effects of phytoestrogens on human pancreatic tumor cells in vitro
- Increased DT-diaphorase activity in transformed and tumorigenic pancreatic acinar cells
Stancy Joseph
National Center for Toxicological Research (US)
4 shared publications
- Expression of drug transporters in human kidney: impact of sex, age, and ethnicity
- Abstract 4428: Metformin effects on ABCB1 expression and proliferation in pancreatic cancer cell lines with different ABCB1 genotypes/haplotypes
- Abstract 770: Gender differences in the expression of drug metabolizing enzymes in human liver tissues
- Abstract 1733: Inhibition of embryonic stem cells gene expression in pancreatic cancer: Effects of metformin and indole-3-carbinol
Li Pang
National Center for Toxicological Research
4 shared publications
In database
- ATP-Binding Cassette Genes Genotype and Expression: A Potential Association with Pancreatic Cancer Development and Chemoresistance?
- Abstract 4428: Metformin effects on ABCB1 expression and proliferation in pancreatic cancer cell lines with different ABCB1 genotypes/haplotypes
- Abstract 759: ATP-binding cassette (ABC) genes genotype and expression: A potential association with pancreatic cancer development and chemoresistance
- Abstract 5376: Expression of histone deacetylases (HDACs) 1, 2, 3 and 7 in pancreatic cancer cell lines: The role of indole-3-carbinol.
Yan Yan-Sanders
National Center for Toxicological Research (US)
3 shared publications
- Increased expression of heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNP) in pancreatic tissue from smokers and pancreatic tumor cells
- Specific site methylation in the 5′-flanking region of CYP1A2
- Increased levels of NAD(P)H: quinone oxidoreductase 1 (NQO1) in pancreatic tissues from smokers and pancreatic adenocarcinomas: A potential biomarker of early damage in the pancreas
Yongmei Xiao
National Center for Toxicological Research (US)
3 shared publications
- Age and gender affect DNMT3a and DNMT3b expression in human liver
- Transcriptional activity of DNMT3B in pancreatic cancer cells: Effects of −149 (C→T) promoter polymorphism
- Cigarette smoke condensate and individual constituents modulate DNA methyltransferase expression in human liver cells
Sulma I. Mohammed
Purdue University West Lafayette (US)
3 shared publications
- Proteomics Profiling of Pancreatic Cancer and Pancreatitis for Biomarkers Discovery
- Abstract 2556: Indole-3-carbinol (I3C) and gemcitabine as potential combinatorial therapy in pancreatic cancer
- Abstract A65: Proteomics of normal, pancreatitis and pancreatic cancer human tissues
Hong‐Gang Wang
National Center for Toxicological Research (US)
3 shared publications
- Cigarette Smoke Condensate Induces Differential Expression and Promoter Methylation Profiles of Critical Genes Involved in Lung Cancer in NL-20 Lung Cells In Vitro
- ATP-Binding Cassette Genes Genotype and Expression: A Potential Association with Pancreatic Cancer Development and Chemoresistance?
- Cytotoxicity of Chronic Exposure to 4 Cigarette Smoke Condensates in 2 Cell Lines
Fatemeh Nouri Emamzaden
National Center for Toxicological Research
3 shared publications
In database
- Abstract 1631: Anti-cancer effects of vorinostat on 3D cultured pancreatic cancer cells
- Abstract 6251: High expression level of GSK3β in basal triple negative breast cancer: Effects of the HDAC inhibitor, vorinostat
- Abstract 4253: High expression of specific gene profiles in organoids from African American pancreatic cancer tumors
Carlos M. Wells
National Center for Toxicological Research
3 shared publications
In database
- Epigenotoxicity of Titanium Dioxide Nanoparticles
- Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells
- Exposure to a Titanium Dioxide Product Alters MicroRNA Expression in Human Cells
Bo Jin
National Center for Toxicological Research (US)
2 shared publications
- Specific site methylation in the 5′-flanking region of CYP1A2
- Increased expression of hepatic DNA methyltransferase in smokers
Similar Researchers
Based on overlapping research topics
Beverly R. Word
National Center for Toxicological Research
Epigenetics and DNA Methylation
Nanoparticles: synthesis and applications
Cancer-related molecular mechanisms research
Beverly D. Lyn‐Cook
National Center for Toxicological Research
Nanoparticles: synthesis and applications
Cancer-related molecular mechanisms research
Health disparities and outcomes
Marta Pogribna
National Center for Toxicological Research
Epigenetics and DNA Methylation
Carcinogens and Genotoxicity Assessment
Nanoparticles: synthesis and applications
Ping Ching Hsu
University of Arkansas for Medical Sciences
Epigenetics and DNA Methylation
Carcinogens and Genotoxicity Assessment
Cancer-related molecular mechanisms research
Tung-Chin Chiang
University of Arkansas for Medical Sciences
Epigenetics and DNA Methylation
Carcinogens and Genotoxicity Assessment
Cancer-related molecular mechanisms research
Volodymyr Tryndyak
National Center for Toxicological Research
Epigenetics and DNA Methylation
Cancer-related molecular mechanisms research
MicroRNA in disease regulation