Match tier Confirmed
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-20

Ruud P.M. Dings

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI High Impact

Researcher

Also affiliated: University of Minnesota (2002–2024); University of Arkansas Medical Center (2026); University of Minnesota System (2006); Maastricht University (2003–2011); Twin Cities Orthopedics (2004–2007); Radiation Oncology Institute (2023); Winthrop Rockefeller Foundation (2014–2025); University of Minnesota Medical Center (2004–2007); Radiation Oncology Associates (2023); Minnesota Department of Health (2002–2013); Institute of Molecular Biology and Biophysics (2006–2012); Arkansas Department of Agriculture (2026)

Faculty Researcher

40 h-index 128 pubs 5,255 cited

  • Animals
  • Mice
  • Humans
  • Angiogenesis Inhibitors
  • Female
  • Peptides
  • Neovascularization, Pathologic
  • Cell Line, Tumor
  • Antineoplastic Agents
  • Neoplasms
  • Proteins
  • Mice, Nude
  • Endothelial Cells
  • Combined Modality Therapy
  • Xenograft Model Antitumor Assays

Biography and Research Information

OverviewAI-generated summary

Ruud P.M. Dings is a researcher at the University of Arkansas for Medical Sciences with a focus on cancer biology and treatment. His work investigates mechanisms underlying tumor growth, immune response to cancer, and the development of novel therapeutic strategies. Dings has received federal funding for research focused on improving cellular immunotherapy in the context of dysbiosis. His laboratory group studies the interplay between the gut microbiome and cancer treatment efficacy, exploring how alterations in microbial communities can impact treatment responses and influence tumor vasculature and sensitivity to therapies like radiotherapy and c-Met inhibitors.

His research also delves into the molecular mechanisms of angiogenesis and tumor cell dormancy, examining factors like VEGF and its inhibitors. Dings has explored the potential of specific peptides and proteins in modulating these processes. Additionally, his publications indicate investigations into the physical and chemical properties of nanomaterials, such as gold nanostructures, and their application in enhancing immune cell function and targeting specific cell populations, as well as their use in photothermal therapy. His work involves studies in animal models, including mice, and human cell lines.

Metrics

  • h-index: 40
  • Publications: 128
  • Citations: 5,255

Selected Publications

  • Synthesis of Peptide Analogs From Fish Venom With Potential Antimicrobial and Anticancer Activity (2026)
    Chemical Biology & Drug Design DOI OpenAlex
  • Abstract 4785: Thermal regulation of dysbiotic tumor vasculature (2026)
    Cancer Research DOI OpenAlex
  • Abstract 7625: Development of a blood-based tumor hypoxia detection assay (2026)
    Cancer Research DOI OpenAlex
  • Modified tumor uptake and biodistribution of nanoparticles coated with small extracellular vesicle membranes derived from distinct tumor cell lines (2026)
    International Journal of Hyperthermia DOI OpenAlex
  • Investigating Biomarkers of Radiation Resistance in Head and Neck Cancer Using Raman Spectroscopy (2025)
  • CB-839 induces reversible dormancy in lung tumor-cells (2024)
    European Journal of Pharmacology 8 citations DOI OpenAlex
  • Bystander Effects in Spatially Fractionated Radiation Therapy: From Molecule To Organism To Clinical Implications (2024)
    Seminars in Radiation Oncology 13 citations DOI OpenAlex
  • Morphological Effects and In Vitro Biological Mechanisms of Radiation-Induced Cell Killing by Gold Nanomaterials (2023)
    ACS Applied Materials & Interfaces 2 citations DOI OpenAlex
  • Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking (2023)
  • Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking (2023)
  • Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy (2022)
    Angiogenesis 54 citations DOI OpenAlex
  • Abstract 3529: T-cell trafficking and extravasation is suppressed in distal tumors during gastrointestinal tract dysbiosis (2022)
    Cancer Research DOI OpenAlex
  • Gold nanorods enhance different immune cells and allow for efficient targeting of CD4+ Foxp3+ Tregulatory cells (2021)
    PLoS ONE 5 citations DOI OpenAlex
  • Nanoscale investigation and control of photothermal action of gold nanostructure-coated surfaces (2021)
    Journal of Materials Science 7 citations DOI OpenAlex
  • Dysbiotic stress increases the sensitivity of the tumor vasculature to radiotherapy and c-Met inhibitors (2021)
    Angiogenesis 4 citations DOI OpenAlex

View all publications on OpenAlex →

Federal Grants 1 $348,182 total

NIH Contact PI Sep 2021 - Aug 2027

Improvement of cellular immunotherapy during dysbiosis- Resubmission

National Cancer Institute $348,182 R01

Collaboration Network

61 Collaborators 19 Institutions 3 Countries

Top Collaborators

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