Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
K
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Katherine Wallis's research focuses on the intersection of diet, metabolism, and cancer treatment, particularly investigating the role of nutrient restriction in enhancing responses to immune checkpoint inhibitors. Her work has explored the impact of methionine depletion on tumor-bearing mice, demonstrating increased sensitivity to immunotherapies in colorectal cancer models. Wallis has also investigated the effects of caloric restriction mimetics and compounds like resveratrol on melanoma treatment, examining their influence on antigen presentation and immune responses. Her experimental approaches include cell culture, in vitro assays, and studies in animal models, involving techniques such as western blots, Seahorse assays, and tissue collection. Wallis has also processed clinical patient samples for research purposes and optimized tumor models. She has a publication record that includes studies on cell death mechanisms, immune checkpoint inhibitors, and melanoma treatment strategies.
Metrics
- h-index: 5
- Publications: 20
- Citations: 130
Positions
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Research Assistant 2021–presentUAMS Medical Center Environmental Health Sciences ORCID
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Research Technician 2019–2021UAMS Medical Center Biochemistry and Molecular Biology ORCID
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Animal Husbandry Technician 2016–2019UAMS Medical Center Department of Laboratory Animal Medicine ORCID
Selected Publications
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Metabolic phenotypes of doxorubicin-induced cardiotoxicity among patients with breast cancer (2026)
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Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy (2026)
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685 EZH2 inhibition impairs CD8+ CAR-T cell persistence (2025)
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691 ATF6 activation promotes ICB response in melanoma (2025)
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762 CD28 costimulation induces PCK2 to support T cell effector function in metabolically hostile environments (2025)
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236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response (2025)
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538 ATF6 activation in melanoma promotes anti-tumor immunity and improves ICB therapy response (2024)
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929 Proteomic analysis reveals differential modulation of the DNA damage response in exhausted T cells (2024)
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932 Defining the role for PCK2 in T-cell metabolic plasticity (2024)
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Abstract 3625: Metabolic phenotypes of doxorubicin-induced cardiotoxicity in breast cancer patients (2024)
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Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma (2023)
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Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model (2023)
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Increased response to immune checkpoint inhibitors with dietary methionine restriction (2023)
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Abstract P3-08-08: Establishment of a Breast Cancer Rat Model of Chemotherapy-Induced Cardiotoxicity (2023)
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Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction (2023)
Collaboration Network
Top Collaborators
Brian Koss
University of Arkansas for Medical Sciences
10 shared publications
In database
- Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma
- Abstract 1577: Caloric restriction mimetics as adjuvant to immune checkpoint inhibitors for treatment of melanoma
- 932 Defining the role for PCK2 in T-cell metabolic plasticity
- 929 Proteomic analysis reveals differential modulation of the DNA damage response in exhausted T cells
- 538 ATF6 activation in melanoma promotes anti-tumor immunity and improves ICB therapy response
Showing 5 of 10 shared publications
Isabelle R. Miousse
University of Arkansas for Medical Sciences
9 shared publications
In database
- Sex-Specific Effects of Dietary Methionine Restriction on the Intestinal Microbiome
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model
- Differences in cell death in methionine versus cysteine depletion
- Increased response to immune checkpoint inhibitors with dietary methionine restriction
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction
Showing 5 of 9 shared publications
Alan J. Tackett
University of Arkansas for Medical Sciences
9 shared publications
In database
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model
- Increased response to immune checkpoint inhibitors with dietary methionine restriction
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction
- Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma
- Methionine stress induces a ferroptotic gene signature in methionine dependent cancer cells
Showing 5 of 9 shared publications
Daniel Fil
University of Arkansas for Medical Sciences
9 shared publications
In database
- Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma
- 932 Defining the role for PCK2 in T-cell metabolic plasticity
- 929 Proteomic analysis reveals differential modulation of the DNA damage response in exhausted T cells
- 538 ATF6 activation in melanoma promotes anti-tumor immunity and improves ICB therapy response
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
Showing 5 of 9 shared publications
Lauren C. Morehead
University of Arkansas for Medical Sciences
6 shared publications
In database
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model
- Differences in cell death in methionine versus cysteine depletion
- Increased response to immune checkpoint inhibitors with dietary methionine restriction
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction
- Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma
Showing 5 of 6 shared publications
Sydnye L. Shuttleworth
University of Arkansas for Medical Sciences
6 shared publications
In database
- 932 Defining the role for PCK2 in T-cell metabolic plasticity
- 929 Proteomic analysis reveals differential modulation of the DNA damage response in exhausted T cells
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
- 762 CD28 costimulation induces PCK2 to support T cell effector function in metabolically hostile environments
- 691 ATF6 activation promotes ICB response in melanoma
Showing 5 of 6 shared publications
Billie Heflin
University of Arkansas for Medical Sciences
5 shared publications
In database
- Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma
- 538 ATF6 activation in melanoma promotes anti-tumor immunity and improves ICB therapy response
- 691 ATF6 activation promotes ICB response in melanoma
- 685 EZH2 inhibition impairs CD8+ CAR-T cell persistence
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
Jacob L Edmondson
University of Arkansas for Medical Sciences
5 shared publications
In database
- 932 Defining the role for PCK2 in T-cell metabolic plasticity
- 538 ATF6 activation in melanoma promotes anti-tumor immunity and improves ICB therapy response
- 762 CD28 costimulation induces PCK2 to support T cell effector function in metabolically hostile environments
- 691 ATF6 activation promotes ICB response in melanoma
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
Sarita Garg
University of Arkansas for Medical Sciences
4 shared publications
In database
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model
- Increased response to immune checkpoint inhibitors with dietary methionine restriction
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction
- Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma
Lora J. Rogers
University of Arkansas for Medical Sciences
4 shared publications
In database
- 932 Defining the role for PCK2 in T-cell metabolic plasticity
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
- 762 CD28 costimulation induces PCK2 to support T cell effector function in metabolically hostile environments
- 685 EZH2 inhibition impairs CD8+ CAR-T cell persistence
Jessica L Kelliher
University of Arkansas for Medical Sciences
4 shared publications
In database
- 932 Defining the role for PCK2 in T-cell metabolic plasticity
- 929 Proteomic analysis reveals differential modulation of the DNA damage response in exhausted T cells
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
- 762 CD28 costimulation induces PCK2 to support T cell effector function in metabolically hostile environments
Megan R. Reed
University of Arkansas for Medical Sciences
4 shared publications
In database
- 538 ATF6 activation in melanoma promotes anti-tumor immunity and improves ICB therapy response
- 691 ATF6 activation promotes ICB response in melanoma
- 685 EZH2 inhibition impairs CD8+ CAR-T cell persistence
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
Eric R. Siegel
University of Arkansas for Medical Sciences
3 shared publications
In database
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model
- Increased response to immune checkpoint inhibitors with dietary methionine restriction
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction
Sam Makhoul
Arkansas Department of Agriculture (US)
3 shared publications
- Abstract P3-08-08: Establishment of a Breast Cancer Rat Model of Chemotherapy-Induced Cardiotoxicity
- Abstract 3625: Metabolic phenotypes of doxorubicin-induced cardiotoxicity in breast cancer patients
- Metabolic phenotypes of doxorubicin-induced cardiotoxicity among patients with breast cancer
Ping-Ching Hsu
Winthrop Rockefeller Foundation
3 shared publications
In database
- Abstract P3-08-08: Establishment of a Breast Cancer Rat Model of Chemotherapy-Induced Cardiotoxicity
- Abstract 3625: Metabolic phenotypes of doxorubicin-induced cardiotoxicity in breast cancer patients
- Metabolic phenotypes of doxorubicin-induced cardiotoxicity among patients with breast cancer
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