Noriko Nakamura

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

High Impact

Researcher

NCTR

Also affiliated: Kanazawa University (1986); Nihon University (2000); Hiroshima University (1984); National Institutes of Health (2007–2009); Research Triangle Park Foundation (2006–2007); Tokai University (2020–2021); United States Food and Drug Administration (2018–2025); Kyushu University (1987–2015); Sapporo Medical University (2002); University of Kansas (2019); Santen (Japan) (2024); Waseda University (2001–2003); University of Illinois Urbana-Champaign (2008–2010); Toyo University (2002); Chiba University (2007); University of Alabama (2000); BioClinica (United States) (1991); Tohoku University (2006–2007); Osaka Medical and Pharmaceutical University (1977); Kyowa Kirin (Japan) (2013); Kyoto University (1994–2000); Kyoto Institute of Technology (1999); Daiichi University of Pharmacy (2006); Tokyo Metropolitan Komagome Hospital (1992–1998); Toray (United States) (2016); Fukuoka University (2011–2014); Triangle (2007–2009); Nishinomiya Municipal Central Hospital (1991); National Institute of Environmental Health Sciences (2006–2009); Novartis (Japan) (2020–2022); Toray Industries, Inc. (Japan) (2003–2022); Osaka Prefectural Institute of Public Health (2024); Osaka Prefectural Toyonaka Support School (2002); Suntory (Japan) (2008–2024); Uji Hospital (1990); Institute of Oriental Manuscripts (1997); Suntory Foundation for Life Sciences (2013); Yokohama Municipal Citizen's Hospital (2000); Tokyo Women's Medical University (1991); National Hospital Organization (2015); Juntendo University Urayasu Hospital (2013–2020); Applied Pharma Research (Switzerland) (2016); Tachikawa Hospital (2004); Saiseikai Fukuoka General Hospital (1998–2005); Food and Drug Administration (2011–2012); Center for Genomic Science (2008); Tokyo Metropolitan Geriatric Hospital (1998); Nagoya Medical Center (2015); Center for Systems Biology (2024); Saiseikai Ibaraki Hospital (1999–2011); Aichi Prefectural Government (2015); Kidney Centre (1987–1992); University of Toyama (2004); Kyoto Min-iren Asukai Hospital (2024); Kyoto Seika University (2018); National Cancer Research Institute (1974); Nagoya University (2001–2015); The University of Tokyo (2000–2025); Marshall University (2011–2014); Kindai University (2004); University of Cincinnati Medical Center (2000); Tokushima University (1996–1997); The University of Osaka (1967–2005)

Faculty Researcher

30 h-index 236 pubs 3,563 cited

Upstream record may be merged OpenAlex, the source of these figures, lists 64 institutions in 8 countries for this author record — a pattern that usually means it combines several researchers with similar names. The totals above may include work by other people.

Research Areas

Biomedical Subjects

Links

ORCID Research Group

OverviewAI-generated summary

Noriko Nakamura's research focuses on pharmacological effects and toxicity studies, with recent work investigating the blood pressure-lowering effects of esaxerenone and trichlormethiazide in patients with uncontrolled hypertension. This includes predefined subanalyses of the EXCITE-HT randomized controlled trial examining the impact of basal calcium channel blocker versus angiotensin receptor blocker use, as well as age subgroups. Nakamura has also contributed to studies on the long-term safety and effectiveness of omalizumab in Japanese pediatric patients with severe allergic asthma and in patients with chronic spontaneous urticaria, based on post-marketing surveillance data.

Further research interests include the development and evaluation of medical imaging probes and models. One publication describes a 64Cu-chelated InP/ZnSe/ZnS quantum dot probe for tumor imaging, utilizing both PET and fluorescence modalities. Another study evaluated a microphysiological human placental barrier model for assessing placental drug transfer. Nakamura also has a publication on a patient-derived monoclonal antibody that neutralizes HCV infection in vitro and in vivo without generating escape mutants.

Nakamura's scholarly output includes 236 publications and 3,533 citations, with an h-index of 30. They are recognized as a highly cited researcher and lead a research group at the National Center for Toxicological Research. Key collaborators include Daniel T. Sloper, Matthew Bryant, Darshan Mehta, and Mani Chidambaram, all from the National Center for Toxicological Research.

Metrics

h-index: 30
Publications: 236
Citations: 3,563

Selected Publications

Alteration of Cytokine/Chemokine Transcript Levels in the Placenta of Humanized Mouse Models Treated Prenatally With Dexamethasone (2025)

DOI OpenAlex
The effect of black cohosh extract and risedronate coadministration on bone health in an ovariectomized rat model (2024)

Frontiers in Pharmacology 2 citations DOI OpenAlex
Evaluation of a microphysiological human placental barrier model for studying placental drug transfer (2023)

Reproductive Toxicology 4 citations DOI OpenAlex
Translational Research for Identifying Potential Early-stage Prostate Cancer Biomarkers (2022)

Cancer Genomics & Proteomics 3 citations DOI OpenAlex
In vivo pharmacokinetic analyses of placental transfer of three drugs of different physicochemical properties in pregnant rats (2022)

Reproductive Toxicology 4 citations DOI OpenAlex
Altered expression of genes identified in rats with prostatic chronic inflammation in a prostate spheroid model treated by estradiol/testosterone (2021)

The Journal of Toxicological Sciences 2 citations DOI OpenAlex
Identification of Altered Proteins in the Plasma of Rats With Chronic Prostatic Inflammation Induced by Estradiol Benzoate and Sex Hormones (2021)

ACS Omega 4 citations DOI OpenAlex
Comparison of germ cell differentiation of rat testis fragments cultured in knockout serum replacement versus Albumax™ I (2020)

Birth Defects Research 7 citations DOI OpenAlex
Distinct lipid signatures are identified in the plasma of rats with chronic inflammation induced by estradiol benzoate and sex hormones (2020)

Metabolomics 7 citations DOI OpenAlex
Gene expression profiling in dorsolateral prostates of prepubertal and adult Sprague-Dawley rats dosed with estradiol benzoate, estradiol, and testosterone (2020)

The Journal of Toxicological Sciences 2 citations DOI OpenAlex
Increased estrogen levels altered microRNA expression in prostate and plasma of rats dosed with sex hormones (2020)

Andrology 16 citations DOI OpenAlex
Gene expression profiling of cultured mouse testis fragments treated with ethinylestradiol (2019)

The Journal of Toxicological Sciences 2 citations DOI OpenAlex
Metabolomics‐based pathway changes in testis fragments treated with ethinylestradiol in vitro (2019)

Birth Defects Research 2 citations DOI OpenAlex
Testicular function in cultured postnatal mouse testis fragments is similar to that of animals during the first wave of spermatogenesis (2019)

Birth Defects Research 22 citations DOI OpenAlex
Evaluation of an in vitro mouse testis organ culture system for assessing male reproductive toxicity (2018)

Birth Defects Research 17 citations DOI OpenAlex