Jon S. Blevins
Professor and Interim Chair
Also affiliated: Oklahoma State University (2005); University of Arkansas Medical Center (2014); Southwestern Medical Center (2005–2008); Instituto de Investigación en Recursos Cinegéticos (2005); Czech Academy of Sciences, Institute of Microbiology (2009); Bipar (1999–2001); The University of Texas Southwestern Medical Center (2004–2010)
Faculty Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Jon S. Blevins' research focuses on bacterial genetics and the molecular mechanisms underlying the physiology and virulence of various pathogens. He has received significant federal funding from the NIH/National Institute of Allergy and Infectious Diseases for his work on tick-borne relapsing fever spirochetes. Specifically, grants have supported the development of genetic manipulation systems for *Borrelia duttonii*, the investigation of cyclic di-AMP signaling in relapsing fever *Borrelia*, and the study of cyclic di-GMP second messenger signaling in *Borrelia turicatae*.
His recent publications demonstrate a consistent focus on bacterial gene regulation and essential cellular processes. Work includes characterizing the diadenylate cyclase CdaA in *Borrelia turicatae* virulence, identifying BB0346 as a crucial component for lipoprotein localization in *Borrelia burgdorferi*, and exploring the regulation of pesticin and type VI secretion systems in *Yersinia pestis*. He also investigates the dispensability of plasmid-encoded genes in *Borrelia burgdorferi* and the role of arthropod-associated lipoproteins in the transmission cycle of *Borrelia turicatae*. Blevins' scholarship metrics include an h-index of 26 with over 3,270 citations across 49 publications, indicating a substantial research output. He collaborates with several researchers at the University of Arkansas for Medical Sciences, including Clay D. Jackson-Litteken, Wanfeng Guo, C. Tyler Ratliff, and Madeleine G. Scott.
Metrics
- h-index: 26
- Publications: 51
- Citations: 3,307
Selected Publications
-
Defining strain variation in the maintenance of <i>Borrelia turicatae</i> during hyperparasitism and transovarial transmission in the tick vector (2026)
-
<i>Yersinia pestis</i> plasminogen activator protease is regulated by the PhoP/PhoQ two-component system (2025)
-
<i>Yersinia pestis</i> BipA is a novel regulator of pesticin and a type 6 secretion system (2025)
-
The plasmid-encoded members of paralogous gene family 52 are dispensable to the enzootic cycle of <i>Borrelia burgdorferi</i> (2024)
-
<i>Borrelia burgdorferi</i> BB0346 is an Essential, Structurally Variant LolA Homolog that is Primarily Required for Homeostatic Localization of Periplasmic Lipoproteins (2024)
-
Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii (2024)
-
Characterization of the arthropod associated lipoprotein (Alp) in the tick-mammalian transmission cycle of Borrelia turicatae (2022)
-
The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology (2021)
-
The BB0345 Hypothetical Protein of Borrelia burgdorferi Is Essential for Mammalian Infection (2020)
-
Assessing the Contribution of an HtrA Family Serine Protease During Borrelia turicatae Mammalian Infection (2019)
-
The RpoS Gatekeeper in Borrelia burgdorferi: An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity (2019)
-
Infection of Primary Human Alveolar Macrophages Alters Staphylococcus aureus Toxin Production and Activity (2019)
-
DksA Controls the Response of the Lyme Disease Spirochete <i>Borrelia burgdorferi</i> to Starvation (2018)
-
DksA controls the response of the Lyme disease spirochete Borrelia burgdorferi to starvation (2018)
-
Generation of Conditional Mutants in Borrelia burgdorferi (2017)
Federal Grants 3 $891,450 total
Cyclic di-AMP-dependent signaling in tickborne relapsing fever Borrelia
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Virulence Mechanisms of Multifunctional Borrelial Proteins NIH/Nat. Inst. of Allergy & Infectious Diseases via East Carolina University
- New genetic approaches analyzing Borrelia burgdorferi NIH
- Center for Microbial Pathogenesis and Host Inflammatory Responses NIH
- Studying the roles of dinucleotide second messenger molecules in the pathogenesis of the tickborne relapsing fever spirochete, Borrelia turicatae UAMS College of Medicine
- Rrp2-dependent gene regulation in Borrelia burgdorferi NIH
- Blevins Start Up Account UAMS College of Medicine
- RpoS-mediated virulence regulation in Borrelia burgdorferi NIH
Collaboration Network
Top Collaborators
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- Characterization of the arthropod associated lipoprotein (Alp) in the tick-mammalian transmission cycle of Borrelia turicatae
- Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii
- Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii
- <i>Yersinia pestis</i> BipA is a novel regulator of pesticin and a type 6 secretion system
- <i>Yersinia pestis</i> plasminogen activator protease is regulated by the PhoP/PhoQ two-component system
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- Characterization of the arthropod associated lipoprotein (Alp) in the tick-mammalian transmission cycle of Borrelia turicatae
- <i>Yersinia pestis</i> BipA is a novel regulator of pesticin and a type 6 secretion system
- <i>Yersinia pestis</i> plasminogen activator protease is regulated by the PhoP/PhoQ two-component system
- <i>Yersinia pestis</i> BipA is a novel regulator of pesticin and a type 6 secretion system
- <i>Yersinia pestis</i> plasminogen activator protease is regulated by the PhoP/PhoQ two-component system
- <i>Yersinia pestis</i> BipA is a novel regulator of pesticin and a type 6 secretion system
- <i>Yersinia pestis</i> plasminogen activator protease is regulated by the PhoP/PhoQ two-component system
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- Characterization of the arthropod associated lipoprotein (Alp) in the tick-mammalian transmission cycle of Borrelia turicatae
- Characterization of the arthropod associated lipoprotein (Alp) in the tick-mammalian transmission cycle of Borrelia turicatae
- Characterization of the arthropod associated lipoprotein (Alp) in the tick-mammalian transmission cycle of Borrelia turicatae
Similar Researchers
Based on overlapping research topics