Lindsay Pack
Senior Analytical Chemist/Lab Manager
University of Arkansas for Medical Sciences
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Biography and Research Information
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Lindsay Pack's research centers on the application of analytical chemistry techniques, particularly metabolomics and mass spectrometry, to investigate complex biological systems. Pack's work has explored the associations between maternal obesity and offspring gut microbiome composition in early life, and the impact of exercise and diet-induced weight loss on hepatic bile acid synthesis in obese women. Further investigations include the role of specific enzymes in microbial physiology and virulence, and the relationship between infant milk intake, growth, and maternal body mass index. Pack has also examined the effects of novel fatty acids in mammalian lipidomes and the physiological changes associated with diabetes progression, such as colonic epithelial hypoxia. Recent work has focused on optimizing untargeted metabolomics methods using orbitrap mass spectrometry for plasma analysis. Pack holds an h-index of 12 with 28 total publications and 562 citations.
Metrics
- h-index: 12
- Publications: 28
- Citations: 562
Selected Publications
- Circulating short- and medium-chain fatty acids in pregnancy and associations with maternal and infant metabolism, inflammation, and body composition (2026) DOI
- Evaluation of Ion Source Parameters and Liquid Chromatography Methods for Plasma Untargeted Metabolomics Using Orbitrap Mass Spectrometer (2024) DOI
- Ion Source Optimization and Lc Separation Method Development for Comprehensive Untargeted Metabolomics Using Orbitrap Mass Spectrometer (2023) DOI
- Associations between maternal obesity and offspring gut microbiome in the first year of life (2022) DOI
- Infant intakes of human milk branched chain amino acids are negatively associated with infant growth and influenced by maternal body mass index (2021) DOI
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology (2021) DOI
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