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Biography and Research Information
OverviewAI-generated summary
Renny S. Lan's research program investigates host-microbiome interactions and metabolic pathways, with a particular focus on the gastrointestinal microbiome and its influence on health and disease. Lan's work utilizes advanced analytical techniques, including tandem mass spectrometry, to conduct untargeted metabolomics studies. Current projects examine how maternal obesity impacts infant gut microbiome development and how exercise training influences xenometabolites in both lean and obese adults. Previously, Lan has investigated the role of iron uptake in bone mass regulation in mice and the critical function of the diadenylate cyclase CdaA in bacterial virulence. Collaborations include numerous publications with Ping-Ching Hsu, Lindsay Pack, Brian D. Piccolo, and Samuel G. Mackintosh at the University of Arkansas for Medical Sciences. Lan has published 54 papers with an h-index of 13 and 881 citations.
Metrics
- h-index: 13
- Publications: 56
- Citations: 907
Selected Publications
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Circulating short- and medium-chain fatty acids in pregnancy and associations with maternal and infant metabolism, inflammation, and body composition (2026)
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Xenometabolomics reveals metabolic functional guilds unique to specific inulin subtypes in human gut microbiota cultures (2025)
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Prenatal Exercise Training Alters Plasma Metabolite Responses To Acute Exercise In Pregnant Women With Obesity (2025)
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Associations Between Serum Gut-Derived Tryptophan Metabolites and Cardiovascular Health Markers in Adolescents with Obesity (2025)
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Beyond the Known Metabolome: Predictive Strategies for Dark Matter Discovery (2025)
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A narrative review of metabolomics approaches in identifying biomarkers of doxorubicin-induced cardiotoxicity (2025)
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Evaluation of ion source parameters and liquid chromatography methods for plasma untargeted metabolomics using orbitrap mass spectrometer (2025)
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Evaluation of Ion Source Parameters and Liquid Chromatography Methods for Plasma Untargeted Metabolomics Using Orbitrap Mass Spectrometer (2024)
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Associations between maternal microbiome, metabolome and incidence of low-birth weight in Guatemalan participants from the Women First Trial (2024)
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Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues (2024)
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The Gut Microbiome Across the Murine Lifespan: Impact of Diet and Its Association With Inflammation, Lipids, Liver Cancer, and Lifespan (2024)
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Colonic epithelial hypoxia remains constant during the progression of diabetes in male UC Davis type 2 diabetes mellitus rats (2024)
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Ion Source Optimization and Lc Separation Method Development for Comprehensive Untargeted Metabolomics Using Orbitrap Mass Spectrometer (2023)
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Optimization of Mass Spectrometric Parameters in Data Dependent Acquisition for Untargeted Metabolomics on the Basis of Putative Assignments (2023)
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Exercise training modifies xenometabolites in gut and circulation of lean and obese adults (2023)
Collaboration Network
Top Collaborators
- Current Practices in LC-MS Untargeted Metabolomics: A Scoping Review on the Use of Pooled Quality Control Samples
- A narrative review of metabolomics approaches in identifying biomarkers of doxorubicin-induced cardiotoxicity
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 16 shared publications
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 2 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 3 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 14 shared publications
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 2 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 3 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 14 shared publications
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 2 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 3 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 14 shared publications
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 2 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 3 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 14 shared publications
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 2 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 3 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 14 shared publications
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 2 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 3 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 14 shared publications
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 2 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 3 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 14 shared publications
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- Infant intakes of human milk branched chain amino acids are negatively associated with infant growth and influenced by maternal body mass index
- Elamipretide treatment during pregnancy ameliorates the progression of polycystic kidney disease in maternal and neonatal mice with PKD1 mutations
- Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues
Showing 5 of 10 shared publications
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Exercise training modifies xenometabolites in gut and circulation of lean and obese adults
- Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues
- Colonic epithelial hypoxia remains constant during the progression of diabetes in male UC Davis type 2 diabetes mellitus rats
- P20-038-23 Colonic Epithelia Hypoxia Remains Constant During the Progression of Diabetes in the UC Davis Type 2 Diabetes Mellitus Rat Model
Showing 5 of 7 shared publications
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Infant intakes of human milk branched chain amino acids are negatively associated with infant growth and influenced by maternal body mass index
- Circulating long-chain acylcarnitine concentrations are not affected by exercise training in pregnant women with obesity
- Infant Intakes of Human Milk Amino Acids Are Associated With Maternal Obesity and Infant Growth
- Prenatal Exercise Training Alters Plasma Metabolite Responses To Acute Exercise In Pregnant Women With Obesity
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Klotho enhances diastolic function in aged hearts through Sirt1-mediated pathways
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Phosphoproteomics Provides Novel Insights into the Response of Primary Acute Lymphoblastic Leukemia Cells to Microtubule Depolymerization in G1 Phase of the Cell Cycle
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Infant intakes of human milk branched chain amino acids are negatively associated with infant growth and influenced by maternal body mass index
- Infant Intakes of Human Milk Amino Acids Are Associated With Maternal Obesity and Infant Growth
- Circulating short- and medium-chain fatty acids in pregnancy and associations with maternal and infant metabolism, inflammation, and body composition
- Infant intakes of human milk branched chain amino acids are negatively associated with infant growth and influenced by maternal body mass index
- Associations Between Serum Gut-Derived Tryptophan Metabolites and Cardiovascular Health Markers in Adolescents with Obesity
- Circulating long-chain acylcarnitine concentrations are not affected by exercise training in pregnant women with obesity
- Prenatal Exercise Training Alters Plasma Metabolite Responses To Acute Exercise In Pregnant Women With Obesity
- Exercise training modifies xenometabolites in gut and circulation of lean and obese adults
- Colonic epithelial hypoxia remains constant during the progression of diabetes in male UC Davis type 2 diabetes mellitus rats
- P20-038-23 Colonic Epithelia Hypoxia Remains Constant During the Progression of Diabetes in the UC Davis Type 2 Diabetes Mellitus Rat Model
- Xenometabolomics reveals metabolic functional guilds unique to specific inulin subtypes in human gut microbiota cultures
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