Giselle Almeida Gonzalez

Researcher

University of Arkansas for Medical Sciences

grad_student

1 h-index 3 pubs 4 cited

Research Areas

Cancer-related molecular mechanisms research Epigenetics and DNA Methylation Genomics and Chromatin Dynamics Child and Adolescent Health Cancer Genomics and Diagnostics Bioinformatics and Genomic Networks

Is this your profile? Verify and claim your profile

OverviewAI-generated summary

Giselle Almeida Gonzalez's research investigates the molecular mechanisms underlying pediatric acute megakaryoblastic leukemia (AML), specifically focusing on the CBFA2T3-GLIS2 fusion and its role in disease progression and therapeutic resistance. Her work has explored how this fusion reprograms enhancer-linked DNA methylation, leading to apoptotic resistance, and has identified this epigenetic vulnerability as a potential target for treatment. Almeida Gonzalez has also studied the epigenetic enhancement of MED12L in ETO2-GLIS2 positive pediatric AML and its association with resistance to CDK8 inhibitors. Her publications in this area highlight transcriptional rewiring driven by enhancer methylation in pediatric AML. Almeida Gonzalez collaborates with researchers including Samrat Roy Choudhury, Arundhati Chavan, Jason Farrar, and Troy Davidson at the University of Arkansas for Medical Sciences.

Metrics

  • h-index: 1
  • Publications: 3
  • Citations: 4

Selected Publications

  • Abstract PR006: CBFA2T3–GLIS2 fusion reprograms enhancer-linked DNA methylation to enforce apoptotic resistance and defines an epigenetic vulnerability in pediatric AML (2026) DOI
  • Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia (2025) DOI
  • Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors (2021) DOI

Collaborators

Researchers in the database who share publications

Samrat Roy Choudhury University of Arkansas for Medical Sciences 3 shared publications Arundhati Chavan University of Arkansas for Medical Sciences 2 shared publications Jason Farrar University of Arkansas for Medical Sciences 1 shared publication Troy Davidson University of Arkansas for Medical Sciences 1 shared publication Dane A. Jester University of Arkansas for Medical Sciences 1 shared publication Dr. Stephanie Byrum University of Arkansas for Medical Sciences 1 shared publication Akhilesh Kaushal University of Arkansas for Medical Sciences 1 shared publication Pritam Biswas University of Arkansas for Medical Sciences 1 shared publication

Similar Researchers

Based on overlapping research topics

Steven Post University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research Epigenetics and DNA Methylation Genomics and Chromatin Dynamics
Strong match 4 shared topics
L. Lynn Harris University of Arkansas at Fayetteville
Cancer-related molecular mechanisms research Genomics and Chromatin Dynamics Cancer Genomics and Diagnostics
Good match 4 shared topics
Akhilesh Kaushal University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research Epigenetics and DNA Methylation Genomics and Chromatin Dynamics
Good match 5 shared topics
Harley, Susan University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research Epigenetics and DNA Methylation Genomics and Chromatin Dynamics
Good match 3 shared topics
Dr. Stephanie Byrum University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research Epigenetics and DNA Methylation Genomics and Chromatin Dynamics
Good match 4 shared topics
Samrat Roy Choudhury University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research Epigenetics and DNA Methylation Genomics and Chromatin Dynamics
Good match 4 shared topics