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Presence Current · Arkansas
Last published 2025
Sources OpenAlex · ORCID
Refreshed 2026-08-18

Bertha Osei

Senior Research Techninian

Also affiliated: Kwame Nkrumah University of Science and Technology (2023); Oklahoma Medical Research Foundation (2019–2024); North Carolina Agricultural and Technical State University (2017–2023)

Faculty Researcher

7 h-index 26 pubs 209 cited

  • Neurons
  • Pyramidal Cells
  • DNA Helicases
  • Saccharomyces cerevisiae
  • Saccharomyces cerevisiae Proteins
  • G-Quadruplexes
  • Pathogen-Associated Molecular Pattern Molecules
  • Lipopolysaccharides
  • Axons
  • Dendrites
  • Hippocampus
  • Mitochondria
  • DNA
  • DNA Replication
  • DNA, Single-Stranded

Biography and Research Information

OverviewAI-generated summary

Bertha Osei's research focuses on neuronal structure and function, particularly the morphology of dendritic mitochondria. Her work investigates how mitochondrial dynamics, including fusion and fission, are regulated in response to neuronal activity and how these processes are influenced by experimental conditions such as fixative choice and oxygen levels during tissue perfusion. Osei has also contributed to research on DNA helicases, specifically the eukaryotic Pif1 helicase, examining its unwinding mechanisms for G-quadruplexes and double-stranded DNA. Additionally, her research has explored the impact of diverse pathogen-associated molecular patterns on gene transcription within the toll-like receptor signaling pathway in goat blood, and she has investigated the cellular effects of rare single nucleotide polymorphisms in the HELB gene.

Metrics

  • h-index: 7
  • Publications: 26
  • Citations: 209

Selected Publications

  • Rare SNP in the <i>HELB</i> gene interferes with RPA interaction and cellular function of HELB (2025)
    NAR Molecular Medicine DOI OpenAlex
  • Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge (2024)
    Nature Communications 9 citations DOI OpenAlex
  • Rare SNP in the <i>HELB</i> gene interferes with RPA interaction and cellular function of HELB (2024)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex

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Collaboration Network

22 Collaborators 6 Institutions 2 Countries

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