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Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-10-05

Emory G. Malone

Graduate Research Assistant

3 h-index 8 pubs 35 cited

  • DNA Helicases
  • Saccharomyces cerevisiae Proteins
  • G-Quadruplexes
  • DNA, Single-Stranded
  • Saccharomyces cerevisiae
  • DNA
  • DNA Replication
  • Viral Proteins
  • Bacteriophage T4
  • Humans
  • Models, Molecular
  • Protein Binding
  • Crystallography, X-Ray
  • Genomic Instability
  • Bacterial Proteins

Biography and Research Information

OverviewAI-generated summary

Emory G. Malone's research focuses on the function and regulation of DNA helicases, particularly the Pif1 family. Their work investigates how these enzymes interact with DNA structures like G-quadruplexes and double-stranded DNA, utilizing conserved mechanisms to unwind them. Malone has also studied the structural features of viral helicases, such as the Dda helicase from bacteriophage T4, and their ability to displace proteins from DNA. Further research includes examining genome editing efficiency and the creation of unintended genetic alterations using CRISPR/Cas9 in model organisms like *Schizosaccharomyces pombe*. Additionally, Malone has investigated factors affecting microbial growth, including yeast spore plating efficiency and transcription factor activation of meiotic recombination hotspots.

Metrics

  • h-index: 3
  • Publications: 8
  • Citations: 35

Positions

  • Graduate Research Assistant 2023–present
    University of Arkansas for Medical Sciences Biochemistry and Molecular Biology ORCID
  • Research Technician 2021–2022
    University of Arkansas for Medical Sciences Biochemistry and Molecular Biology ORCID

Selected Publications

  • Abstract 3871 Transcription factor Toe2 activates the meiotic recombination hotspot 4156 (2026)
    Journal of Biological Chemistry DOI OpenAlex
  • Agar lot-specific inhibition in the plating efficiency of yeast spores and cells (2024)
    G3 Genes Genomes Genetics 1 citation DOI OpenAlex
  • Distance-dependent effects on CRISPR/Cas9-mediated genome editing in Schizosaccharomyces pombe compromise efficiency and create unsought alleles (2024)
    PubMed 2 citations DOI OpenAlex
  • Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge (2024)
    Nature Communications 10 citations DOI OpenAlex
  • DNA sequences and distinct mechanisms for ura4-595 and ura4-294 alleles of S. pombe (2024)
    PubMed DOI OpenAlex
  • Role and Regulation of Pif1 Family Helicases at the Replication Fork (2022)
    International Journal of Molecular Sciences 14 citations DOI OpenAlex
  • Monitoring helicase-catalyzed unwinding of multiple duplexes simultaneously (2022)
    Methods in enzymology on CD-ROM/Methods in enzymology DOI OpenAlex
  • A structural feature of Dda helicase which enhances displacement of streptavidin and trp repressor from DNA (2021)
    Protein Science 8 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

22 Collaborators 9 Institutions 3 Countries

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