Match tier
Likely match
Presence
Current · Arkansas
Last published
2022
Sources
OpenAlex · ORCID
Refreshed
2026-10-06
C
Carrie L. Moland
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
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Also affiliated: United States Food and Drug Administration (1999–2022); Procter & Gamble (United States) (2003)
28 h-index
47 pubs
3,405 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Carrie L. Moland's research focuses on investigating the mechanisms and biomarkers of drug-induced cardiotoxicity, particularly in relation to the chemotherapeutic agent doxorubicin. Her work utilizes animal models, specifically mice and rats, to study gene expression changes and identify potential early indicators of cardiac damage. Recent publications have explored the delayed-onset and chronic effects of doxorubicin on the heart, including subclinical cardiotoxicity in mice.
Further research by Moland has examined sex-related differences in doxorubicin-induced cardiotoxicity, investigating the role of specific molecular pathways such as the apelin-APJ system. Additionally, her studies have identified microRNA-34a-5p as a potential circulating biomarker for early detection of doxorubicin-induced chronic cardiotoxicity. Moland's scholarship includes 47 publications and an h-index of 28, with her work being highly cited. She has collaborated with researchers at the National Center for Toxicological Research on multiple shared publications.
Metrics
- h-index: 28
- Publications: 47
- Citations: 3,405
Selected Publications
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Potential role of the apelin‐APJ pathway in sex‐related differential cardiotoxicity induced by doxorubicin in mice (2022)
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MicroRNA‐34a‐5p as a promising early circulating preclinical biomarker of doxorubicin‐induced chronic cardiotoxicity (2022)
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Doxorubicin‐induced delayed‐onset subclinical cardiotoxicity in mice (2021)
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Candidate early predictive plasma protein markers of doxorubicin-induced chronic cardiotoxicity in B6C3F1 mice (2018)
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Sex and age differences in the expression of liver microRNAs during the life span of F344 rats (2017)
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Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice (2016)
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Early metabolomics changes in heart and plasma during chronic doxorubicin treatment in B6C3F1 mice (2016)
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Early transcriptional changes in cardiac mitochondria during chronic doxorubicin exposure and mitigation by dexrazoxane in mice (2016)
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Reproductive hormone levels and differential mitochondria-related oxidative gene expression as potential mechanisms for gender differences in cardiosensitivity to Doxorubicin in tumor-bearing spontaneously hypertensive rats (2015)
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Age and sex differences in kidney microRNA expression during the life span of F344 rats (2015)
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Sexual Dimorphism in the Expression of Mitochondria-Related Genes in Rat Heart at Different Ages (2015)
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Human Sex Hormone-Binding Globulin Binding Affinities of 125 Structurally Diverse Chemicals and Comparison with Their Binding to Androgen Receptor, Estrogen Receptor, and α-Fetoprotein (2014)
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Early biomarkers of doxorubicin-induced heart injury in a mouse model (2014)
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A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages (2014)
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Sex differences in kidney gene expression during the life cycle of F344 rats (2013)
Collaboration Network
Top Collaborators
James C. Fuscoe
National Center for Toxicological Research
31 shared publications
In database
- A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
- Development of doxorubicin-induced chronic cardiotoxicity in the B6C3F1 mouse model
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Age and sex dependent changes in liver gene expression during the life cycle of the rat
- Age and sex differences in kidney microRNA expression during the life span of F344 rats
Showing 5 of 31 shared publications
Varsha G. Desai
National Center for Toxicological Research
29 shared publications
In database
- Transgenic expression of proximal tubule peroxisome proliferator–activated receptor-α in mice confers protection during acute kidney injury
- Development of doxorubicin-induced chronic cardiotoxicity in the B6C3F1 mouse model
- Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Age and sex dependent changes in liver gene expression during the life cycle of the rat
Showing 5 of 29 shared publications
William S. Branham
National Center for Toxicological Research (US)
23 shared publications
- Structure−Activity Relationships for a Large Diverse Set of Natural, Synthetic, and Environmental Estrogens
- A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
- Study of 202 Natural, Synthetic, and Environmental Chemicals for Binding to the Androgen Receptor
- QSAR Models Using a Large Diverse Set of Estrogens
- Transgenic expression of proximal tubule peroxisome proliferator–activated receptor-α in mice confers protection during acute kidney injury
Showing 5 of 23 shared publications
Taewon Lee
Korea University (KR)
17 shared publications
- Transgenic expression of proximal tubule peroxisome proliferator–activated receptor-α in mice confers protection during acute kidney injury
- Development of doxorubicin-induced chronic cardiotoxicity in the B6C3F1 mouse model
- Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Effect of (+)-usnic acid on mitochondrial functions as measured by mitochondria-specific oligonucleotide microarray in liver of B6C3F1 mice
Showing 5 of 17 shared publications
Vikrant Vijay
National Center for Toxicological Research
14 shared publications
In database
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Age and sex differences in kidney microRNA expression during the life span of F344 rats
- Sexual Dimorphism in the Expression of Mitochondria-Related Genes in Rat Heart at Different Ages
- Sex differences in kidney gene expression during the life cycle of F344 rats
- Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice
Showing 5 of 14 shared publications
Tao Han
National Center for Toxicological Research (US)
11 shared publications
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Elimination of laboratory ozone leads to a dramatic improvement in the reproducibility of microarray gene expression measurements.
- The Liver Toxicity Biomarker Study: Phase I Design and Preliminary Results
- Improvement in the Reproducibility and Accuracy of DNA Microarray Quantification by Optimizing Hybridization Conditions
- Early transcriptional changes in cardiac mitochondria during chronic doxorubicin exposure and mitigation by dexrazoxane in mice
Showing 5 of 11 shared publications
Sherry M. Lewis
National Center for Toxicological Research
8 shared publications
In database
- Development of doxorubicin-induced chronic cardiotoxicity in the B6C3F1 mouse model
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Effect of (+)-usnic acid on mitochondrial functions as measured by mitochondria-specific oligonucleotide microarray in liver of B6C3F1 mice
- Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice
- Early transcriptional changes in cardiac mitochondria during chronic doxorubicin exposure and mitigation by dexrazoxane in mice
Showing 5 of 8 shared publications
Joshua C. Kwekel
National Center for Toxicological Research (US)
7 shared publications
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Age and sex dependent changes in liver gene expression during the life cycle of the rat
- Age and sex differences in kidney microRNA expression during the life span of F344 rats
- Sexual Dimorphism in the Expression of Mitochondria-Related Genes in Rat Heart at Different Ages
- Sex differences in kidney gene expression during the life cycle of F344 rats
Showing 5 of 7 shared publications
Hong Fang
National Center for Toxicological Research
6 shared publications
In database
- Structure−Activity Relationships for a Large Diverse Set of Natural, Synthetic, and Environmental Estrogens
- Study of 202 Natural, Synthetic, and Environmental Chemicals for Binding to the Androgen Receptor
- QSAR Models Using a Large Diverse Set of Estrogens
- Human Sex Hormone-Binding Globulin Binding Affinities of 125 Structurally Diverse Chemicals and Comparison with Their Binding to Androgen Receptor, Estrogen Receptor, and α-Fetoprotein
- Changes in expression level of genes as a function of time of day in the liver of rats
Showing 5 of 6 shared publications
Daniel M. Sheehan
National Center for Toxicological Research (US)
6 shared publications
- Structure−Activity Relationships for a Large Diverse Set of Natural, Synthetic, and Environmental Estrogens
- Study of 202 Natural, Synthetic, and Environmental Chemicals for Binding to the Androgen Receptor
- QSAR Models Using a Large Diverse Set of Estrogens
- Human Sex Hormone-Binding Globulin Binding Affinities of 125 Structurally Diverse Chemicals and Comparison with Their Binding to Androgen Receptor, Estrogen Receptor, and α-Fetoprotein
- Rat α-Fetoprotein Binding Affinities of a Large Set of Structurally Diverse Chemicals Elucidated the Relationships between Structures and Binding Affinities
Showing 5 of 6 shared publications
Weida Tong
National Center for Toxicological Research
6 shared publications
In database
- Structure−Activity Relationships for a Large Diverse Set of Natural, Synthetic, and Environmental Estrogens
- Study of 202 Natural, Synthetic, and Environmental Chemicals for Binding to the Androgen Receptor
- QSAR Models Using a Large Diverse Set of Estrogens
- Human Sex Hormone-Binding Globulin Binding Affinities of 125 Structurally Diverse Chemicals and Comparison with Their Binding to Androgen Receptor, Estrogen Receptor, and α-Fetoprotein
- Rat α-Fetoprotein Binding Affinities of a Large Set of Structurally Diverse Chemicals Elucidated the Relationships between Structures and Binding Affinities
Showing 5 of 6 shared publications
Eugene H. Herman
National Cancer Institute (UA)
6 shared publications
- Development of doxorubicin-induced chronic cardiotoxicity in the B6C3F1 mouse model
- Early biomarkers of doxorubicin-induced heart injury in a mouse model
- Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice
- Early transcriptional changes in cardiac mitochondria during chronic doxorubicin exposure and mitigation by dexrazoxane in mice
- Candidate early predictive plasma protein markers of doxorubicin-induced chronic cardiotoxicity in B6C3F1 mice
Showing 5 of 6 shared publications
Roger Perkins
National Center for Toxicological Research (US)
5 shared publications
- Structure−Activity Relationships for a Large Diverse Set of Natural, Synthetic, and Environmental Estrogens
- Study of 202 Natural, Synthetic, and Environmental Chemicals for Binding to the Androgen Receptor
- QSAR Models Using a Large Diverse Set of Estrogens
- Human Sex Hormone-Binding Globulin Binding Affinities of 125 Structurally Diverse Chemicals and Comparison with Their Binding to Androgen Receptor, Estrogen Receptor, and α-Fetoprotein
- Rat α-Fetoprotein Binding Affinities of a Large Set of Structurally Diverse Chemicals Elucidated the Relationships between Structures and Binding Affinities
Huixiao Hong
National Center for Toxicological Research
4 shared publications
In database
- A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
- Study of 202 Natural, Synthetic, and Environmental Chemicals for Binding to the Androgen Receptor
- Human Sex Hormone-Binding Globulin Binding Affinities of 125 Structurally Diverse Chemicals and Comparison with Their Binding to Androgen Receptor, Estrogen Receptor, and α-Fetoprotein
- Rat α-Fetoprotein Binding Affinities of a Large Set of Structurally Diverse Chemicals Elucidated the Relationships between Structures and Binding Affinities
Robert R. Delongchamp
National Center for Toxicological Research
4 shared publications
In database
- Changes in expression level of genes as a function of time of day in the liver of rats
- Nucleoside reverse transcriptase inhibitors (NRTIs)-induced expression profile of mitochondria-related genes in the mouse liver
- Development of mitochondria-specific mouse oligonucleotide microarray and validation of data by real-time PCR
- 18 Effect of neonatal exposure of 3′-azido-3′-deoxythymidine on the expression level of mitochondrial genes in the skeletal muscle of mouse as measured by mitochondria-specific microarray
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