Sherry M. Lewis Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Researcher

National Center for Toxicological Research

faculty

24 h-index 60 pubs 2,694 cited

Research Areas

Pharmacological Effects and Toxicity Studies Carcinogens and Genotoxicity Assessment Metabolism and Genetic Disorders Diet and metabolism studies Neuroscience and Neuropharmacology Research

Links

ORCID

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OverviewAI-generated summary

Sherry M. Lewis's research focuses on the toxicological assessment of chemical compounds, particularly in the context of inhalation exposure and various administration routes in Sprague-Dawley rats. Her work investigates the toxicokinetic and genotoxic effects of specific substances, including NNK (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone), a known carcinogen. Lewis has published studies examining the pharmacokinetics of nicotine and its metabolites following different exposure methods such as nose-only inhalation, oral gavage, and intravenous infusion.

Her research also includes conducting sub-chronic toxicity studies, such as 14-day and 90-day nose-only inhalation toxicity assessments of NNK. These studies contribute to understanding the dose-response relationships and potential health impacts of these chemicals. Lewis has also been involved in peer review for toxicological studies, demonstrating engagement with the broader scientific community. Her scholarly contributions are reflected in her h-index of 24, with 60 total publications and 2,694 citations, designating her as a highly cited researcher.

Metrics

  • h-index: 24
  • Publications: 60
  • Citations: 2,694

Selected Publications

  • Pharmacokinetic analysis of nicotine and its metabolites (cotinine and <i>trans</i>-3′-hydroxycotinine) in male Sprague-Dawley rats following nose-only inhalation, oral gavage, and intravenous infusion of nicotine (2024) DOI
  • 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats (2021) DOI
  • 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats (2021) DOI
  • Toxicokinetic and Genotoxicity Study of NNK in Male Sprague Dawley Rats Following Nose-Only Inhalation Exposure, Intraperitoneal Injection, and Oral Gavage (2021) DOI

Collaborators

Researchers in the database who share publications

Matthew Bryant National Center for Toxicological Research 4 shared publications Shu-Chieh Hu National Center for Toxicological Research 4 shared publications Hyun-Ki Kang National Center for Toxicological Research 4 shared publications Paul C. Howard National Center for Toxicological Research 4 shared publications Seonggi Min National Center for Toxicological Research 3 shared publications Dong-Jin Yang National Center for Toxicological Research 3 shared publications Raúl Trbojevich National Center for Toxicological Research 3 shared publications Mason G. Pearce National Center for Toxicological Research 3 shared publications

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