Sherry M. Lewis Data-verified

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Researcher

NCTR
Last publication 2024 Last refreshed 2026-05-16

faculty

24 h-index 60 pubs 2,713 cited

Research Areas

Links

ORCID

OverviewAI-generated summary

Sherry M. Lewis's research focuses on the toxicological effects and pharmacokinetic profiles of various substances, primarily utilizing rodent models. Her work has investigated the toxicokinetic and genotoxicity of NNK (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone), a tobacco-specific nitrosamine, in male Sprague Dawley rats. Studies have examined these effects following different exposure routes, including nose-only inhalation, intraperitoneal injection, and oral gavage. Lewis has also conducted pharmacokinetic analyses of nicotine and its metabolites in rats, comparing data from nose-only inhalation, oral gavage, and intravenous infusion.

Further research includes 14-day and 90-day nose-only inhalation toxicity studies of NNK in Sprague-Dawley rats, also assessing Haber's Rule in the context of NNK exposure. Her scholarly contributions are reflected in an h-index of 24, with 60 total publications and over 2,600 citations. She has collaborated with several researchers at the National Center for Toxicological Research, including Matthew Bryant, Shu-Chieh Hu, Hyun-Ki Kang, and Paul C. Howard, with whom she shares four publications each.

Metrics

  • h-index: 24
  • Publications: 60
  • Citations: 2,713

Selected Publications

  • Pharmacokinetic analysis of nicotine and its metabolites (cotinine and <i>trans</i>-3′-hydroxycotinine) in male Sprague-Dawley rats following nose-only inhalation, oral gavage, and intravenous infusion of nicotine (2024)
    7 citations DOI OpenAlex
  • 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats (2021)
    4 citations DOI OpenAlex
  • 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats (2021)
    7 citations DOI OpenAlex
  • Toxicokinetic and Genotoxicity Study of NNK in Male Sprague Dawley Rats Following Nose-Only Inhalation Exposure, Intraperitoneal Injection, and Oral Gavage (2021)
    13 citations DOI OpenAlex

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Collaboration Network

45 Collaborators 4 Institutions 1 Country

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