Sherry M. Lewis

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

High Impact

Researcher

NCTR primary UA Pine Bluff

Also affiliated: California Institute of Technology (1993–1994); United States Food and Drug Administration (2008–2024); University of Wisconsin–Madison (1951); University of Toronto (1999); Hospital for Sick Children (1999); Park University (2021); Bionetics (United States) (1995–2004); SickKids Foundation (1999); Food and Drug Administration (2008)

Faculty Researcher

24 h-index 60 pubs 2,751 cited

Research Areas

Biomedical Subjects

Links

ORCID

OverviewAI-generated summary

Sherry M. Lewis's research focuses on the toxicological effects and pharmacokinetic profiles of various substances, primarily utilizing rodent models. Her work has investigated the toxicokinetic and genotoxicity of NNK (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone), a tobacco-specific nitrosamine, in male Sprague Dawley rats. Studies have examined these effects following different exposure routes, including nose-only inhalation, intraperitoneal injection, and oral gavage. Lewis has also conducted pharmacokinetic analyses of nicotine and its metabolites in rats, comparing data from nose-only inhalation, oral gavage, and intravenous infusion.

Further research includes 14-day and 90-day nose-only inhalation toxicity studies of NNK in Sprague-Dawley rats, also assessing Haber's Rule in the context of NNK exposure. Her scholarly contributions are reflected in an h-index of 24, with 60 total publications and over 2,600 citations. She has collaborated with several researchers at the National Center for Toxicological Research, including Matthew Bryant, Shu-Chieh Hu, Hyun-Ki Kang, and Paul C. Howard, with whom she shares four publications each.

Metrics

h-index: 24
Publications: 60
Citations: 2,751

Selected Publications

Pharmacokinetic analysis of nicotine and its metabolites (cotinine and <i>trans</i>-3′-hydroxycotinine) in male Sprague-Dawley rats following nose-only inhalation, oral gavage, and intravenous infusion of nicotine (2024)

Toxicological Sciences 8 citations DOI OpenAlex
90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats (2021)

Food and Chemical Toxicology 6 citations DOI OpenAlex
14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats (2021)

Toxicological Sciences 7 citations DOI OpenAlex
Toxicokinetic and Genotoxicity Study of NNK in Male Sprague Dawley Rats Following Nose-Only Inhalation Exposure, Intraperitoneal Injection, and Oral Gavage (2021)

Toxicological Sciences 15 citations DOI OpenAlex
A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results (2019)

Food and Chemical Toxicology 62 citations DOI OpenAlex
Candidate early predictive plasma protein markers of doxorubicin-induced chronic cardiotoxicity in B6C3F1 mice (2018)

Toxicology and Applied Pharmacology 23 citations DOI OpenAlex
Gene expression and DNA methylation changes in the hypothalamus and hippocampus of adult rats developmentally exposed to bisphenol A or ethinyl estradiol: a CLARITY-BPA consortium study (2018)

Epigenetics 59 citations DOI OpenAlex
Effects of continuous bisphenol A exposure from early gestation on 90 day old rat testes function and sperm molecular profiles: A CLARITY-BPA consortium study (2018)

Toxicology and Applied Pharmacology 37 citations DOI OpenAlex
Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice (2016)

Toxicology and Applied Pharmacology 40 citations DOI OpenAlex
Early transcriptional changes in cardiac mitochondria during chronic doxorubicin exposure and mitigation by dexrazoxane in mice (2016)

Toxicology and Applied Pharmacology 34 citations DOI OpenAlex
Effects of oral exposure to bisphenol A on gene expression and global genomic DNA methylation in the prostate, female mammary gland, and uterus of NCTR Sprague-Dawley rats (2015)

Food and Chemical Toxicology 24 citations DOI OpenAlex
Effects of developmental exposure to bisphenol A on spatial navigational learning and memory in rats: A CLARITY-BPA study (2015)

Hormones and Behavior 85 citations DOI OpenAlex
NIEHS/FDA CLARITY-BPA research program update (2015)

Reproductive Toxicology 100 citations DOI OpenAlex
Investigation of the Effects of Subchronic Low Dose Oral Exposure to Bisphenol A (BPA) and Ethinyl Estradiol (EE) on Estrogen Receptor Expression in the Juvenile and Adult Female Rat Hypothalamus (2014)

Toxicological Sciences 83 citations DOI OpenAlex
Early biomarkers of doxorubicin-induced heart injury in a mouse model (2014)

Toxicology and Applied Pharmacology 96 citations DOI OpenAlex