Xiaolun Sun

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Associate Professor

University of Arkansas primary UA Div. of Agriculture

Also affiliated: University of North Carolina at Chapel Hill (2009–2020); University of Florida Health (2013–2018); University of Florida (2013–2019); Virginia Tech (2005–2007)

Poultry Science

21 h-index 64 pubs 1,810 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website

OverviewAI-generated summary

Xiaolun Sun is an Assistant Professor in Poultry Science at the Arkansas Agricultural Experiment Station. His research focuses on the interplay between host-microbe interactions and immune responses, particularly concerning gastrointestinal health in poultry and its relevance to human health.

Sun's work investigates the mechanisms by which specific bacteria, such as *Clostridium perfringens* and *Salmonella Enteritidis*, influence host health. This includes studying the role of microbial metabolites, like secondary bile acids, in modulating bacterial virulence and host immune responses. He has published research examining how compounds such as sodium butyrate and natural compounds like resveratrol can impact host defense pathways, including the NF-κB signaling pathway, and affect inflammation and vascular function in models involving mice and human endothelial cells.

His research also extends to the development of strategies to prevent and control enteric diseases in poultry. This includes exploring the efficacy of vaccines based on bacterial sporulation proteins and the use of recombinant enzymes to enhance the effectiveness of antimicrobial compounds. Sun's scholarship metrics include an h-index of 21 and over 1,700 citations across 64 publications. He actively collaborates with researchers at the University of Arkansas at Fayetteville.

Metrics

h-index: 21
Publications: 64
Citations: 1,810

Positions

Associate Professor 2023–present

University of Arkansas UADA | POSC | Department of Poultry Science ORCID
Assistant Professor 2016–present

University of Arkansas Fayetteville Poultry Science ORCID
Research Assistant Professor 2013–2016

University of Florida Medicine ORCID
Postdoc 2008–2013

University of North Carolina at Chapel Hill Medicine ORCID

Selected Publications

The Mechanistic Target of Rapamycin Mediates Clostridium perfringens-Induced Chicken Necrotic Enteritis Attenuated by Secondary Bile Acid Deoxycholic Acid (2025)

Microorganisms 1 citation DOI OpenAlex
Identification of Salt Tolerance and Stress Response in US Department of Agriculture Tomato Germplasm at the Seedling Stage (2024)

HortScience 3 citations DOI OpenAlex
Recombinant Bile Salt Hydrolase Enhances the Inhibition Efficiency of Taurodeoxycholic Acid against Clostridium perfringens Virulence (2024)

Pathogens 6 citations DOI OpenAlex
Potent Bile Acid Microbial Metabolites Modulate Clostridium perfringens Virulence (2023)

Pathogens 8 citations DOI OpenAlex
Essential Oils as an Alternative to Antibiotics to Reduce the Incidence and Severity of Necrotic Enteritis in Broiler Chickens: A Short Review (2023)

Food and Nutrition Sciences 7 citations DOI OpenAlex
Vaccines Using Clostridium perfringens Sporulation Proteins Reduce Necrotic Enteritis in Chickens (2022)

Microorganisms 11 citations DOI OpenAlex
Clostridium perfringens-Induced Necrotic Diseases: An Overview (2022)

Immuno 41 citations DOI OpenAlex
Triterpenoid CDDO-IM protects against lipopolysaccharide-induced inflammatory response and cytotoxicity in macrophages: The involvement of the NF-κB signaling pathway (2022)

Experimental Biology and Medicine 1 citation DOI OpenAlex
Natural Compound Resveratrol Attenuates TNF-Alpha-Induced Vascular Dysfunction in Mice and Human Endothelial Cells: The Involvement of the NF-κB Signaling Pathway (2021)

International Journal of Molecular Sciences 33 citations DOI OpenAlex
Microbiota from Specific Pathogen-Free Mice Reduces Campylobacter jejuni Chicken Colonization (2021)

Pathogens 3 citations DOI OpenAlex
Specific Secondary Bile Acids Control Chicken Necrotic Enteritis (2021)

Pathogens 32 citations DOI OpenAlex
Sodium butyrate modulates chicken macrophage proteins essential for Salmonella Enteritidis invasion (2021)

PLoS ONE 15 citations DOI OpenAlex
Microbiota attenuates chicken transmission-exacerbated campylobacteriosis in Il10−/− mice (2020)

Scientific Reports 7 citations DOI OpenAlex
Sodium Butyrate Reduces Salmonella Enteritidis Infection of Chicken Enterocytes and Expression of Inflammatory Host Genes in vitro (2020)

Frontiers in Microbiology 35 citations DOI OpenAlex
Role of Gut Microbiome in Colorectal Cancer (2020)

DOI OpenAlex