Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Ponmari Guruvaiah's research focuses on the molecular mechanisms underlying hepatocellular carcinoma, a form of liver cancer. Their work investigates the role of the orphan nuclear receptor NR2E3 and its impact on the Wnt/β-catenin signaling pathway. A key publication details how the loss of NR2E3 augments this signaling pathway through epigenetic dysregulation, specifically by enhancing interactions between Sp1, β-catenin, and p300. This molecular interplay is implicated in the progression of hepatocellular carcinoma.
Guruvaiah collaborates with researchers at the University of Arkansas for Medical Sciences, including Kyounghyun Kim, Shuk-Mei Ho, Yuet‐Kin Leung, and Nancy J. Rusch. Their scholarship metrics include an h-index of 1 with one publication and nine total citations.
Metrics
- h-index: 1
- Publications: 1
- Citations: 9
Selected Publications
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The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β‐catenin Signaling via Epigenetic Dysregulation that Enhances Sp1‐β catenin‐p300 Interactions in Hepatocellular Carcinoma (2024)
Collaboration Network
Top Collaborators
- The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β‐catenin Signaling via Epigenetic Dysregulation that Enhances Sp1‐β catenin‐p300 Interactions in Hepatocellular Carcinoma
- The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β‐catenin Signaling via Epigenetic Dysregulation that Enhances Sp1‐β catenin‐p300 Interactions in Hepatocellular Carcinoma
- The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β‐catenin Signaling via Epigenetic Dysregulation that Enhances Sp1‐β catenin‐p300 Interactions in Hepatocellular Carcinoma
- The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β‐catenin Signaling via Epigenetic Dysregulation that Enhances Sp1‐β catenin‐p300 Interactions in Hepatocellular Carcinoma
- The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β‐catenin Signaling via Epigenetic Dysregulation that Enhances Sp1‐β catenin‐p300 Interactions in Hepatocellular Carcinoma
- The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β‐catenin Signaling via Epigenetic Dysregulation that Enhances Sp1‐β catenin‐p300 Interactions in Hepatocellular Carcinoma
- The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β‐catenin Signaling via Epigenetic Dysregulation that Enhances Sp1‐β catenin‐p300 Interactions in Hepatocellular Carcinoma
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