Match tier Listed
Presence Current · Arkansas
Last published 2024
Sources OpenAlex · ORCID
Refreshed 2026-08-17

Denise Fabiano do Nascimento

Researcher

Graduate Student Researcher

1 h-index 3 pubs 11 cited

  • Aortic Valve
  • Aortic Valve Stenosis
  • Calcinosis
  • Cholesterol
  • Lab-On-A-Chip Devices
  • Microphysiological Systems
  • Animals
  • Cell Cycle
  • Extracellular Matrix
  • Homeostasis
  • Humans
  • Swine
  • Disease Progression
  • Coculture Techniques
  • Hydrogels

Biography and Research Information

OverviewAI-generated summary

Denise Fabiano do Nascimento's research investigates the progression of calcific aortic valve disease, focusing on the roles of cell cycle progression, cholesterol metabolism, and protein homeostasis. This work utilizes a three-dimensional valve-on-chip microphysiological system, a lab-on-a-chip device designed to mimic biological conditions. Recent publications also explore the utility of recombinant fragment E8 of laminin-511 as a replacement for Matrigel in human induced pluripotent stem cell culture and differentiation into neurovascular cell types. Nascimento collaborates with researchers at the University of Arkansas at Fayetteville, including Ishita Tandon and Kartik Balachandran, with whom they have co-authored multiple publications. Their scholarly output includes three publications with a total of 11 citations and an h-index of 1.

Metrics

  • h-index: 1
  • Publications: 3
  • Citations: 11

Selected Publications

  • The future is fully defined: recombinant fragment E8 of laminin-511 is a viable xenofree alternative to Matrigel for hiPSC culture and differentiation into neurovascular cell types (2024)
    Research Square DOI OpenAlex
  • A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression (2024)
    Acta Biomaterialia 10 citations DOI OpenAlex
  • The future is fully defined: recombinant fragment E8 of laminin-511 is a viable xenofree alternative to Matrigel for hiPSC culture and differentiation into neurovascular cell types (2024)
    bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex

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Collaboration Network

20 Collaborators 7 Institutions 1 Country

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