Rushita A. Bagchi

High Impact

Assistant Professor

University of Arkansas for Medical Sciences

faculty

26 h-index 91 pubs 1,672 cited

Research Areas

Epigenetics and DNA Methylation Cardiovascular Function and Risk Factors Mitochondrial Function and Pathology Diet and metabolism studies Pharmacological Effects and Toxicity Studies Acute Kidney Injury Fibrosis Research

Links

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OverviewAI-generated summary

Rushita A. Bagchi's research investigates the molecular mechanisms underlying cardiovascular and renal dysfunction, with a particular focus on the role of epigenetic modifications. Her work has explored how histone deacetylase (HDAC) inhibition can reverse existing diastolic dysfunction and prevent long-term cardiorenal outcomes following acute kidney injury. Bagchi has also examined the impact of HDAC inhibition on metabolic pathways, specifically its potential to restore leptin sensitivity and reduce obesity.

Her recent publications also delve into the cellular processes contributing to fibrosis in various organs. This includes studying the role of mitochondrial uncoupling protein-2 in age-associated lung fibrosis and investigating the involvement of scleraxis in pressure-overloaded hearts. Bagchi's research group also studies sex-based differences in cardiorenal outcomes after ischemia-reperfusion injury and explores the regulation of adipocyte signaling through protein fatty acylation. Bagchi holds a h-index of 26 with over 1,600 citations across 91 publications.

Metrics

  • h-index: 26
  • Publications: 91
  • Citations: 1,672

Selected Publications

  • 3-D biomechanics and epigenomics reveal atypical fibroblast responses in cardiometabolic disease (2025) DOI
  • Temporal Dynamics of Extracellular Matrix Remodeling in Anthracycline-Induced Cardiotoxicity (2025) DOI
  • Interplay between stress, chloride homeostasis, and cardiovascular regulation (2025) DOI
  • Simulating Cardiometabolic Disease in a 3D-Microenvironment: Human Cardiac Fibroblast Response to Nutritional Stress (2025) DOI
  • Global Transcriptional Profiling of Adipose Tissue Uncovers Unique Sex-Dependent Mechanisms in Acute Obesity: Implications for Adipose-Heart Interorgan Crosstalk (2025) DOI
  • Obesity, histone acetylation, and insulin resistance (2024) DOI
  • List of contributors (2024) DOI
  • Histone Deacetylases in Metabolism: the Known and the Unexplored (2024) DOI
  • Proteomics Approach to Identify Anthracycline-induced Cardiotoxicity Mechanisms in Human Cardiac Fibroblasts (2024) DOI
  • Scleraxis and fibrosis in the pressure-overloaded heart (2022) DOI

Grants & Funding

Collaborators

Researchers in the database who share publications

Shahnaz Ibrahim University of Arkansas for Medical Sciences 3 shared publications Ashim K. Bagchi University of Arkansas for Medical Sciences 3 shared publications Se-Ran Jun University of Arkansas for Medical Sciences 2 shared publications Fibi Meshrkey University of Arkansas at Fayetteville 1 shared publication Neha S. Dole University of Arkansas for Medical Sciences 1 shared publication Marguerite K. Shepard University of Arkansas for Medical Sciences 1 shared publication Amanda J. Stolarz University of Arkansas for Medical Sciences 1 shared publication Jayden Carter University of Arkansas for Medical Sciences 1 shared publication

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