Rushita A. Bagchi
Assistant Professor
Also affiliated: Griffith University (2017); University of Burdwan (2015); MACOM (United States) (2021); University of Colorado Boulder (2022); Gold Coast Hospital (2017); Cystic Fibrosis Trust (2023); St. Boniface Hospital (2011–2018); The Medical Center of Aurora (2024); University of Manitoba (2011–2018); University of Colorado Anschutz Medical Campus (2016–2024); University of Colorado Denver (2013–2022)
Faculty Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Rushita A. Bagchi's research group at the University of Arkansas for Medical Sciences investigates mechanisms of cardiovascular and renal disease, with a particular focus on the role of epigenetic modifications and metabolic reprogramming. Her work has explored how histone deacetylase (HDAC) inhibition can reverse pre-existing diastolic dysfunction and prevent long-term consequences of acute kidney injury, such as chronic diastolic dysfunction. Her group has also examined the impact of mitochondrial uncoupling protein-2 on age-associated lung fibrosis and investigated the differential long-term cardiorenal outcomes in male and female mice following ischemia-reperfusion injury.
Additional research interests include the cellular remodeling processes in the pressure-overloaded heart, such as the roles of scleraxis and fibrosis. The group has also studied the metabolic consequences of acute kidney injury, including increased oxidative stress and altered energy production. Bagchi's scholarship metrics include an h-index of 26, with 1,758 total citations across 96 publications. She is recognized as a highly cited researcher and collaborates with Shahnaz Ibrahim, Ashim K. Bagchi, and Se-Ran Jun at the University of Arkansas for Medical Sciences.
Metrics
- h-index: 26
- Publications: 97
- Citations: 1,793
Selected Publications
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Cardiac Fibroblasts in Extracellular Matrix Homeostasis and Remodeling (2026)
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Uncovering a novel cell death-independent mechanism of acute anthracycline toxicity in human cardiac fibroblasts (2026)
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Sex-Specific Adipose Transcriptomic Reprogramming Drives Early Inter-Organ Remodeling in Heart and Liver Under Nutrient Excess (2026)
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Hidden Receptor Crosstalk Governs Lymphatic Failure After Cancer Therapy (2026)
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A call to redefine cardiovascular immunobiology around leukocyte plasticity (2026)
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A Defined and Cost-Efficient Strategy for Generating Functionally Quiescent Human iPSC-Derived Cardiac Fibroblasts (2026)
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3-D biomechanics and epigenomics reveal atypical fibroblast responses in cardiometabolic disease (2025)
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Temporal Dynamics of Extracellular Matrix Remodeling in Anthracycline-Induced Cardiotoxicity (2025)
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Interplay between stress, chloride homeostasis, and cardiovascular regulation (2025)
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Simulating Cardiometabolic Disease in a 3D-Microenvironment: Human Cardiac Fibroblast Response to Nutritional Stress (2025)
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Global Transcriptional Profiling of Adipose Tissue Uncovers Unique Sex-Dependent Mechanisms in Acute Obesity: Implications for Adipose-Heart Interorgan Crosstalk (2025)
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Obesity, histone acetylation, and insulin resistance (2024)
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List of contributors (2024)
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Histone Deacetylases in Metabolism: the Known and the Unexplored (2024)
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Proteomics Approach to Identify Anthracycline-induced Cardiotoxicity Mechanisms in Human Cardiac Fibroblasts (2024)
Grants & Funding
As listed on this researcher's institutional profile.
- Research Training Award American Physiological Society
- Mapping the interactome of a lysine demyristoylase in the diabetic heart Brunson Endowment Grant for Cardiovascular Diseases Research/UAMS College of Medicine
- Elucidation of the regulatory role of scleraxis in cardiac fibrosis (Funded by: Canadian Institutes of Health Research (CIHR)/Research Manitoba Predoctoral Research Award)
- HDAC11 in Diabetic Cardiomyopathy American Heart Association Career Development Award
- ABI P. Prather NIH T32 FY26 Y3 State of Arkansas
- A Multi-omics Approach to Identify Mechanisms of HDAC11 mediated Lipid Regulation in the Diabetic Heart Sturgis Endowment Grant for Diabetes Research/UAMS College of Medicine
- Epigenetic regulation of cardiac hypertrophy by BET acetyl-lysine binding proteins (Funded by: Canadian Institutes of Health Research (CIHR) Postdoctoral Research Fellowship)
Collaboration Network
Top Collaborators
- 3-D biomechanics and epigenomics reveal atypical fibroblast responses in cardiometabolic disease
- Proteomics Approach to Identify Anthracycline-induced Cardiotoxicity Mechanisms in Human Cardiac Fibroblasts
- Global Transcriptional Profiling of Adipose Tissue Uncovers Unique Sex-Dependent Mechanisms in Acute Obesity: Implications for Adipose-Heart Interorgan Crosstalk
- Simulating Cardiometabolic Disease in a 3D-Microenvironment: Human Cardiac Fibroblast Response to Nutritional Stress
- Proteomics Approach to Identify Anthracycline-induced Cardiotoxicity Mechanisms in Human Cardiac Fibroblasts
- List of contributors
- Obesity, histone acetylation, and insulin resistance
- Proteomics Approach to Identify Anthracycline-induced Cardiotoxicity Mechanisms in Human Cardiac Fibroblasts
- List of contributors
- Obesity, histone acetylation, and insulin resistance
- Histone Deacetylases in Metabolism: the Known and the Unexplored
- Global Transcriptional Profiling of Adipose Tissue Uncovers Unique Sex-Dependent Mechanisms in Acute Obesity: Implications for Adipose-Heart Interorgan Crosstalk
- Simulating Cardiometabolic Disease in a 3D-Microenvironment: Human Cardiac Fibroblast Response to Nutritional Stress
- 3-D biomechanics and epigenomics reveal atypical fibroblast responses in cardiometabolic disease
- Global Transcriptional Profiling of Adipose Tissue Uncovers Unique Sex-Dependent Mechanisms in Acute Obesity: Implications for Adipose-Heart Interorgan Crosstalk
- Simulating Cardiometabolic Disease in a 3D-Microenvironment: Human Cardiac Fibroblast Response to Nutritional Stress
- Temporal Dynamics of Extracellular Matrix Remodeling in Anthracycline-Induced Cardiotoxicity
- 3-D biomechanics and epigenomics reveal atypical fibroblast responses in cardiometabolic disease
- Interplay between stress, chloride homeostasis, and cardiovascular regulation
- 3-D biomechanics and epigenomics reveal atypical fibroblast responses in cardiometabolic disease
- Simulating Cardiometabolic Disease in a 3D-Microenvironment: Human Cardiac Fibroblast Response to Nutritional Stress
- Scleraxis and fibrosis in the pressure-overloaded heart
- Scleraxis and fibrosis in the pressure-overloaded heart
- Scleraxis and fibrosis in the pressure-overloaded heart
- Scleraxis and fibrosis in the pressure-overloaded heart
- Scleraxis and fibrosis in the pressure-overloaded heart
- Scleraxis and fibrosis in the pressure-overloaded heart
- Scleraxis and fibrosis in the pressure-overloaded heart
- Scleraxis and fibrosis in the pressure-overloaded heart
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