Mary Qu Yang
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Professor - STEM
Also affiliated: Oak Ridge National Laboratory (2008); United States Department of Health and Human Services (2006–2009); National Institutes of Health (2006–2010); National Institute of Standards and Technology (2019); Harvard University (2007–2009); University of Toronto (2013); Cornell University (2021); Purdue University West Lafayette (2003–2010); University of Arkansas System (2017); Yale University (2017); Massachusetts General Hospital (2007); National Human Genome Research Institute (2006–2010); Weill Cornell Medicine (2021); Indiana University Indianapolis (2008–2010); Oak Ridge Institute for Science and Education (2008); Indiana University School of Medicine (2008–2010); Indiana University – Purdue University Indianapolis (2010)
Information Science
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Mary Qu Yang's research focuses on the application of computational methods to biological and medical problems, with a particular emphasis on genomics, gene regulation, and machine learning. She has published extensively on topics including the analysis of gene expression data, prediction of DNA and RNA-binding residues in proteins, and the annotation of bidirectional promoters to understand gene co-regulation in cancers.
Her work has contributed to the understanding of gene regulation mediated by microRNAs in response to specific compounds in cancer models and has involved the evaluation of analytical methods for circulating tumor DNA sequencing in precision oncology. Yang leads a research group and is recognized as a highly cited researcher with an h-index of 30 and over 5,000 citations from nearly 200 publications. She has established collaborations with researchers at the National Center for Toxicological Research and the University of Arkansas for Medical Sciences.
Metrics
- h-index: 31
- Publications: 191
- Citations: 5,288
Positions
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Professor - STEM publications 2014–2025University of Arkansas at Little Rock Information Science Institutional directory
Selected Publications
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Single-Cell Transcriptomic Analysis Unveils Key Regulators and Signaling Pathways in Lung Adenocarcinoma Progression (2025)
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Characterizing the Tumor Microenvironment and Its Prognostic Impact in Breast Cancer (2024)
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Novel Thienopyrimidine-Hydrazinyl Compounds Induce DRP1-Mediated Non-Apoptotic Cell Death in Triple-Negative Breast Cancer Cells (2024)
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cnnImpute: missing value recovery for single cell RNA sequencing data (2024)
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A Deep Learning-Based Model for Gene Regulatory Network Inference (2023)
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Analysis of Single-Cell RNA Sequencing Data Unveils Novel Immune Prognostic Biomarkers (2023)
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Exploring Barriers to Diversity, Equity, and Inclusion in Communication Sciences and Disorders Students (2023)
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Additional file 2 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples (2022)
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Additional file 3 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples (2022)
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Integrating Single-Cell Transcriptome and Network Analysis to Characterize the Therapeutic Response of Chronic Myeloid Leukemia (2022)
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Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples (2022)
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Missing Value Recovery for Single Cell RNA Sequencing Data (2021)
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Gene Regulation Analysis Reveals Perturbations of Autism Spectrum Disorder during Neural System Development (2021)
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Brain Tumor Segmentation Using Deep Neural Networks and Survival Prediction (2021)
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Merging Deep Learning and Data Analytics for Inferring Coronavirus Human Adaptive Transmutability and Transmissibility (2021)
ARA Academy 2023 ARA Fellow
Dr. Yang established the Systems Genomics Laboratory at UALR. She holds degrees in engineering, physics, electrical and computer engineering, and a PhD in Computational Science and Physics from Purdue University. She completed postdoctoral training in Human Genomics and Bioinformatics at the National Human Genome Research Institute (NHGRI) and worked as a Research Fellow there from 2008-2012.
Policy Impact
Established the MidSouth Bioinformatics Center at UALR, building computational genomics infrastructure that supports health research and precision medicine across the state.
Growth Areas
['Population Health Innovations & Clinical Research']
Collaboration Network
Top Collaborators
- Identification of genes and pathways involved in kidney renal clear cell carcinoma
- The emerging genomics and systems biology research lead to systems genomics studies
- A new statistical approach to combining p-values using gamma distribution and its application to genome-wide association study
- Genomic analyses based on pulmonary adenocarcinoma in situ reveal early lung cancer signature
- Association of six CpG-SNPs in the inflammation-related genes with coronary heart disease
Showing 5 of 29 shared publications
- Identification of genes and pathways involved in kidney renal clear cell carcinoma
- The emerging genomics and systems biology research lead to systems genomics studies
- A new statistical approach to combining p-values using gamma distribution and its application to genome-wide association study
- Genomic analyses based on pulmonary adenocarcinoma in situ reveal early lung cancer signature
- Association of six CpG-SNPs in the inflammation-related genes with coronary heart disease
Showing 5 of 21 shared publications
- Image Captioning with Bidirectional Semantic Attention-Based Guiding of Long Short-Term Memory
- Genomic analyses based on pulmonary adenocarcinoma in situ reveal early lung cancer signature
- Multi-label Deep Learning for Gene Function Annotation in Cancer Pathways
- Transcription Factor and lncRNA Regulatory Networks Identify Key Elements in Lung Adenocarcinoma
- MISC: missing imputation for single-cell RNA sequencing data
Showing 5 of 18 shared publications
- Identification of genes and pathways involved in kidney renal clear cell carcinoma
- The emerging genomics and systems biology research lead to systems genomics studies
- The clinical significance of snail protein expression in gastric cancer: a meta-analysis
- A Gene Module-Based eQTL Analysis Prioritizing Disease Genes and Pathways in Kidney Cancer
- A hotspots analysis-relation discovery representation model for revealing diabetes mellitus and obesity
Showing 5 of 14 shared publications
- Gene regulation mediated by microRNAs in response to green tea polyphenol EGCG in mouse lung cancer
- Identification of genes and pathways involved in kidney renal clear cell carcinoma
- Increased AURKA promotes cell proliferation and predicts poor prognosis in bladder cancer
- MicroRNA and messenger RNA profiling reveals new biomarkers and mechanisms for RDX induced neurotoxicity
- Association of six CpG-SNPs in the inflammation-related genes with coronary heart disease
Showing 5 of 11 shared publications
- Identification of genes and pathways involved in kidney renal clear cell carcinoma
- The emerging genomics and systems biology research lead to systems genomics studies
- A Gene Module-Based eQTL Analysis Prioritizing Disease Genes and Pathways in Kidney Cancer
- Toward precision breast cancer survival prediction utilizing combined whole genome-wide expression and somatic mutation analysis
- Advances in translational bioinformatics facilitate revealing the landscape of complex disease mechanisms
Showing 5 of 11 shared publications
- Identification of genes and pathways involved in kidney renal clear cell carcinoma
- From Blockchain to Internet-Based Voting
- The clinical significance of snail protein expression in gastric cancer: a meta-analysis
- Advances in translational bioinformatics facilitate revealing the landscape of complex disease mechanisms
- Developing Secure Privacy Preserving and Causal Genetic Alteration Research in Building an Innovative Systematic Pedagogy for Integrated Research and Education: The INSPIRE Model
Showing 5 of 7 shared publications
- Identification of genes and pathways involved in kidney renal clear cell carcinoma
- The emerging genomics and systems biology research lead to systems genomics studies
- A new statistical approach to combining p-values using gamma distribution and its application to genome-wide association study
- Advances in translational bioinformatics facilitate revealing the landscape of complex disease mechanisms
- The emerging genomics and systems biology research lead to systems genomics studies
Showing 5 of 7 shared publications
- Identification of genes and pathways involved in kidney renal clear cell carcinoma
- The emerging genomics and systems biology research lead to systems genomics studies
- The up-regulation of Myb may help mediate EGCG inhibition effect on mouse lung adenocarcinoma
- An Integrative Approach Revealing the Landscape of Long Noncoding RNAs in Human Brain
- The upregulation of Myb and Peg3 may mediate EGCG inhibition effect on mouse lung adenocarcinoma
Showing 5 of 7 shared publications
- The up-regulation of Myb may help mediate EGCG inhibition effect on mouse lung adenocarcinoma
- A hotspots analysis-relation discovery representation model for revealing diabetes mellitus and obesity
- Developing Secure Privacy Preserving and Causal Genetic Alteration Research in Building an Innovative Systematic Pedagogy for Integrated Research and Education: The INSPIRE Model
- Prediction of the efficacy of Wuji Pills by machine learning methods
- Secure Privacy Preserving across Personal Health Data and Single Cell Genomics Research INSPIRE Academic Pedagogy — Merging Big Data Multiplatform with Deep Learning
Showing 5 of 7 shared publications
- From Blockchain to Internet-Based Voting
- Byzantine fault tolerance for collaborative editing with commutative operations
- High-throughput state-machine replication using software transactional memory
- Dependability enhancing mechanisms for integrated clinical environments
- Developing Secure Privacy Preserving and Causal Genetic Alteration Research in Building an Innovative Systematic Pedagogy for Integrated Research and Education: The INSPIRE Model
Showing 5 of 7 shared publications
- Identification and characterization of conserved lncRNAs in human and rat brain
- Transcription Factor and lncRNA Regulatory Networks Identify Key Elements in Lung Adenocarcinoma
- Systems biology analysis reveals new insights into invasive lung cancer
- Comprehensive analysis of pulmonary adenocarcinoma in situ (AIS) revealed new insights into lung cancer progression
- Correction to: Identification and characterization of conserved lncRNAs in human and rat brain
Showing 5 of 7 shared publications
- Image Captioning with Bidirectional Semantic Attention-Based Guiding of Long Short-Term Memory
- Multi-label Deep Learning for Gene Function Annotation in Cancer Pathways
- A hotspots analysis-relation discovery representation model for revealing diabetes mellitus and obesity
- Feature space learning model
- A Knowledge Base Completion Model Based on Path Feature Learning
Showing 5 of 7 shared publications
- Identification of genes and pathways involved in kidney renal clear cell carcinoma
- The emerging genomics and systems biology research lead to systems genomics studies
- Advances in translational bioinformatics facilitate revealing the landscape of complex disease mechanisms
- The emerging genomics and systems biology research lead to systems genomics studies
- Advances in translational bioinformatics facilitate revealing the landscape of complex disease mechanisms
Showing 5 of 6 shared publications
- Identification of genes and pathways involved in kidney renal clear cell carcinoma
- The emerging genomics and systems biology research lead to systems genomics studies
- Advances in translational bioinformatics facilitate revealing the landscape of complex disease mechanisms
- The emerging genomics and systems biology research lead to systems genomics studies
- Advances in translational bioinformatics facilitate revealing the landscape of complex disease mechanisms
Showing 5 of 6 shared publications
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