Andrea M. Moerman-Herzog
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Postdoctoral Fellow
Also affiliated: University of Arkansas Medical Center (2020); John L. McClellan Memorial Veterans Hospital (1993–1999); Saint Louis University (1997–1998)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
A. Moerman's research investigates molecular mechanisms underlying neurological and cellular processes, with a focus on gene expression and signaling pathways. Recent work has explored the role of the reelin signaling pathway in cognitive function, demonstrating how a central repeat fragment can rescue deficits in mouse models of reelin deficiency. This research also examines the modulation of apolipoprotein E receptor-2 by various factors, including ApoE4 and amyloid β-peptide, suggesting a common point of impact in Alzheimer's disease pathogenesis. Additionally, Moerman has contributed to studies on cutaneous T-cell lymphoma, investigating the differential regulation of gene expression by normal and cancer fibroblasts. Other research interests include transcriptomic profiling of peripheral blood mononuclear cells and CD4+ T cells from Sézary syndrome patients, and the impact of next-generation sequencing strategies on diagnosing rare cardiovascular conditions such as Fabry disease and hereditary transthyretin amyloidosis.
Moerman's scholarly output includes 60 publications with 1,310 citations and an h-index of 21. Key collaborators include Syed Hassan Mehdi and Henry N. C. Wong from the University of Arkansas for Medical Sciences, with whom Moerman has co-authored multiple publications. Other collaborators include Steven W. Barger from the University of Arkansas for Medical Sciences and Pascale Richard from the University of Arkansas at Little Rock. Moerman has been recently active, with publications extending to 2026.
Metrics
- h-index: 14
- Publications: 35
- Citations: 605
Positions
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Postdoctoral Fellow 2015–presentUniversity of Arkansas for Medical Sciences Dermatology ORCID
Selected Publications
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Modulation of apolipoprotein E receptor-2 by ApoE4, amyloid β-peptide, reelin, and secreted amyloid precursor protein: a common point of impact in Alzheimer’s disease pathogenesis (2026)
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Central repeat fragment of reelin leads to active reelin intracellular signaling and rescues cognitive deficits in a mouse model of reelin deficiency (2023)
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867 Epigenomic and gene expression defects in sezary syndrome (2022)
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Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling (2021)
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Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling (2021)
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Normal and cancer fibroblasts differentially regulate TWIST1, TOX and cytokine gene expression in cutaneous T-cell lymphoma (2021)
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Normal and Cancer Fibroblasts Differentially Regulate Cytokine Genes and TWIST1 and TOX Expression in Cutaneous T-cell Lymphoma (2020)
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Gene Expression Comparison between Sézary Syndrome and Lymphocytic-Variant Hypereosinophilic Syndrome Refines Biomarkers for Sézary Syndrome (2020)
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154 Shared CpG methylation defects in mycosis fungoides and Sézary syndrome (2020)
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Transcriptome analysis of Sézary syndrome and lymphocytic-variant hypereosinophilic syndrome T cells reveals common and divergent genes (2019)
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1037 Transcriptome analysis in Sézary syndrome and lymphocytic variant hypereosinophilic syndrome identify common and unique genes (2019)
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222 DNA methylomic profiles of TWIST1, PLS3 and GATA6 genes in Sezary Syndrome (2018)
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129 Cutaneous T cell lymphoma tumor cells expanded in vitro retain expression of biomarker genes (2017)
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Presenilin 1 mutations influence processing and trafficking of the ApoE receptor apoER2 (2016)
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NFκB‐inducing kinase inhibits NFκB activity specifically in neurons of the CNS (2016)
Collaboration Network
Top Collaborators
- Unique aspects of transcriptional regulation in neurons - nuances in NFkappaB and Sp1-related factors
- Characterization of a neuronal κB-binding factor distinct from NF-κB
- Neuronal κB-binding Factors Consist of Sp1-related Proteins
- Presenilin 1 mutations influence processing and trafficking of the ApoE receptor apoER2
- NFκB‐inducing kinase inhibits NFκB activity specifically in neurons of the CNS
Showing 5 of 10 shared publications
- Normal and cancer fibroblasts differentially regulate TWIST1, TOX and cytokine gene expression in cutaneous T-cell lymphoma
- Gene Expression Comparison between Sézary Syndrome and Lymphocytic-Variant Hypereosinophilic Syndrome Refines Biomarkers for Sézary Syndrome
- Transcriptome analysis of Sézary syndrome and lymphocytic-variant hypereosinophilic syndrome T cells reveals common and divergent genes
- 129 Cutaneous T cell lymphoma tumor cells expanded in vitro retain expression of biomarker genes
- 222 DNA methylomic profiles of TWIST1, PLS3 and GATA6 genes in Sezary Syndrome
Showing 5 of 10 shared publications
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- Early Defensive Mechanisms against Human Papillomavirus Infection
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- Cross-Reactivity, Epitope Spreading, andDe NovoImmune Stimulation Are Possible Mechanisms of Cross-Protection of Nonvaccine Human Papillomavirus (HPV) Types in Recipients of HPV Therapeutic Vaccines
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3.
- Normal and cancer fibroblasts differentially regulate TWIST1, TOX and cytokine gene expression in cutaneous T-cell lymphoma
- Gene Expression Comparison between Sézary Syndrome and Lymphocytic-Variant Hypereosinophilic Syndrome Refines Biomarkers for Sézary Syndrome
- Normal and Cancer Fibroblasts Differentially Regulate Cytokine Genes and TWIST1 and TOX Expression in Cutaneous T-cell Lymphoma
- Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
- Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- Cross-Reactivity, Epitope Spreading, andDe NovoImmune Stimulation Are Possible Mechanisms of Cross-Protection of Nonvaccine Human Papillomavirus (HPV) Types in Recipients of HPV Therapeutic Vaccines
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3.
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- Cross-Reactivity, Epitope Spreading, andDe NovoImmune Stimulation Are Possible Mechanisms of Cross-Protection of Nonvaccine Human Papillomavirus (HPV) Types in Recipients of HPV Therapeutic Vaccines
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3.
- Unique aspects of transcriptional regulation in neurons - nuances in NFkappaB and Sp1-related factors
- Characterization of a neuronal κB-binding factor distinct from NF-κB
- Neuronal κB-binding Factors Consist of Sp1-related Proteins
- NFκB‐inducing kinase inhibits NFκB activity specifically in neurons of the CNS
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3.
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3.
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3.
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3.
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3.
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3.
- Transcriptome analysis of Sézary syndrome and lymphocytic-variant hypereosinophilic syndrome T cells reveals common and divergent genes
- 222 DNA methylomic profiles of TWIST1, PLS3 and GATA6 genes in Sezary Syndrome
- 1037 Transcriptome analysis in Sézary syndrome and lymphocytic variant hypereosinophilic syndrome identify common and unique genes
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3.
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