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Presence Current · Arkansas
Last published 2022
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Amal Shoeib

Researcher

Also affiliated: Mansoura University (2015–2016); University of Arkansas Medical Center (2021)

Faculty Researcher

5 h-index 10 pubs 71 cited

  • Humans
  • Cannabinoids
  • Indoles
  • Receptor, Cannabinoid, CB2
  • Receptor, Cannabinoid, CB1
  • Dose-Response Relationship, Drug
  • Structure-Activity Relationship
  • Male
  • Microsomes, Liver
  • Recombinant Proteins
  • Ligands
  • Cell Line, Tumor
  • Prostatic Neoplasms
  • Calibration
  • Microinjections

Biography and Research Information

OverviewAI-generated summary

Amal Shoeib's research focuses on the pharmacology of cannabinoid receptors and their potential as therapeutic targets, particularly in cancer treatment. Her work investigates the structure-activity relationships of novel compounds designed to selectively target cannabinoid receptors, such as CB1 and CB2. Shoeib has examined the expression and function of these receptors in various cancer cell lines, including Ewing sarcoma and prostate cancer cells, exploring their role in mediating cell death. Her recent publications detail the synthesis and molecular characterization of indole-based compounds as selective CB2 receptor antagonists and the identification of non-canonical cannabinoid receptors involved in cancer cell death. Shoeib has a h-index of 5, with 10 publications and 71 citations. She collaborates with several researchers at the University of Arkansas for Medical Sciences, including Paul L. Prather, Shengyu Mu, Alicja Urbaniak, and Azure L. Yarbrough.

Metrics

  • h-index: 5
  • Publications: 10
  • Citations: 71

Selected Publications

  • Non-Canonical Cannabinoid Receptors with Distinct Binding and Signaling Properties in Prostate and Other Cancer Cell Types Mediate Cell Death (2022)
    International Journal of Molecular Sciences 3 citations DOI OpenAlex
  • Characterization of cannabinoid receptors expressed in Ewing sarcoma TC-71 and A-673 cells as potential targets for anti-cancer drug development (2021)
    Life Sciences 5 citations DOI OpenAlex
  • Natural and Synthetic Cannabinoids Reduce Cell Viability of Ewing Sarcoma TC‐71 Cells Potentially via Non‐canonical CB receptors (2021)
    The FASEB Journal DOI OpenAlex
  • Synthesis, Molecular Pharmacology, and Structure–Activity Relationships of 3-(Indanoyl)indoles as Selective Cannabinoid Type 2 Receptor Antagonists (2021)
    Journal of Medicinal Chemistry 20 citations DOI OpenAlex
  • 7-Azaindolequinuclidinones (7-AIQD): A novel class of cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptor ligands (2020)
    Bioorganic & Medicinal Chemistry Letters 6 citations DOI OpenAlex
  • Metabolism, CB1 cannabinoid receptor binding and in vivo activity of synthetic cannabinoid 5F-AKB48: Implications for toxicity (2020)
    Pharmacology Biochemistry and Behavior 17 citations DOI OpenAlex
  • Enzymatic analysis of glucuronidation of synthetic cannabinoid 1-naphthyl 1-(4-fluorobenzyl)-1H-indole-3-carboxylate (FDU-PB-22) (2019)
    Xenobiotica 4 citations DOI OpenAlex
  • Quantitative microinjection using fluorescence calibration of streaming microdroplets on a superhydrophobic surface (2018)
    Experimental Cell Research 1 citation DOI OpenAlex

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Collaboration Network

16 Collaborators 5 Institutions 2 Countries

Top Collaborators

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