Amy Y. Sato

Assistant Professor

UAMS

Also affiliated: University of Indianapolis (2016–2017); Central Arkansas Veterans Healthcare System (2022–2024); Richard L. Roudebush VA Medical Center (2024); Indiana Hemophilia and Thrombosis Center (2017); Indiana University School of Medicine (2014–2024); Indiana University – Purdue University Indianapolis (2014–2024)

Faculty Researcher

Physiology & Cell Biology, College of Medicine

14 h-index 43 pubs 1,222 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website UAMS TRI Profile

OverviewAI-generated summary

Amy Y. Sato is an Assistant Professor in the Department of Physiology & Cell Biology at the University of Arkansas for Medical Sciences. Her research focuses on bone metabolism and the impact of various therapeutic interventions on bone health, particularly in the context of metabolic disorders and drug-induced bone loss. Dr. Sato has investigated the effects of anabolic therapies on reversing diabetic bone signatures in mice and explored the potential of novel bone-targeted inhibitors, such as BT-Amide, for preventing glucocorticoid-induced bone loss.

Her work also delves into the cellular mechanisms regulating bone mass and strength, including the role of autophagy regulators like Tfeb in osteoblast lineage cells and the influence of lipocalin-2 on osteocyte ferroptosis and osteoblast crosstalk. Dr. Sato's publication record includes studies on the comparative efficacy of different anabolic agents, such as abaloparatide and teriparatide, in treating type 1 diabetic mice. Her scholarship metrics include an h-index of 14, with 43 publications and 1,165 citations. She has established collaborations with several researchers at her institution, including Teresita Bellido, Nisreen Akel, Gaston Troncoso, and Betiana Perez.

Metrics

h-index: 14
Publications: 43
Citations: 1,222

Selected Publications

Osteocytic Lipocalin-2 regulates bone formation locally through iron-dependent ferroptosis and Wnt suppression (2026)

Cell Death Discovery DOI OpenAlex
Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength (2025)

JCI Insight 11 citations DOI OpenAlex
Lipocalin-2 Regulates Osteocyte Ferroptosis and Osteocyte-Osteoblast Crosstalk via Wnt Signaling to Control Bone Formation (2025)

Research Square 1 citation DOI OpenAlex
Generation of BT-Amide, a Bone-Targeted Pyk2 Inhibitor, Effective <i>via</i> Oral Administration, for the Prevention of Glucocorticoid-Induced Bone Loss (2024)

Journal of Medicinal Chemistry 4 citations DOI OpenAlex
Pharmacologic or genetic interference with atrogene signaling protects against glucocorticoid-induced musculoskeletal and cardiac disease (2024)

JCI Insight 2 citations DOI OpenAlex
CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength (2024)

bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
Editorial: Pathophysiology of bone and mineral metabolism (2024)

Frontiers in Physiology DOI OpenAlex
Abaloparatide is more potent than teriparatide in restoring bone mass and strength in type 1 diabetic male mice (2024)

Bone 5 citations DOI OpenAlex
OR29-04 Vitamin D Signaling Prevents Glucocorticoid-Induced Musculoskeletal Tissue Loss And Cardiac Dysfunction By Targeting The Atrogene Pathway (2023)

Journal of the Endocrine Society 1 citation DOI OpenAlex
THU346 Repairing Skeletal Deterioration In Diabetes With Bone Anabolic Therapies (2023)

Journal of the Endocrine Society DOI OpenAlex
Author Correction: Reversal of the diabetic bone signature with anabolic therapies in mice (2023)

Bone Research 2 citations DOI OpenAlex
Author Correction: Reversal of the diabetic bone signature with anabolic therapies in mice (2023)

Bone Research DOI OpenAlex
Reversal of the diabetic bone signature with anabolic therapies in mice (2023)

Bone Research 28 citations DOI OpenAlex
Myogenic tissue nanotransfection improves muscle torque recovery following volumetric muscle loss (2022)

npj Regenerative Medicine 10 citations DOI OpenAlex
Skeletal Protection and Promotion of Microbiome Diversity by Dietary Boosting of the Endogenous Antioxidant Response (2020)

Journal of Bone and Mineral Research 19 citations DOI OpenAlex

View all publications on OpenAlex →

Grants & Funding

As listed on this researcher's institutional profile.

TRI KL2 Scholars award - Sato UAMS Internal Research Awards Principal Investigator
Center for Musculoskeletal Disease Research (CMDR) NIH/Nat. Inst. of General Medical Sciences Principal Investigator
Sato ASBMR 2025 Young Investigator Travel Award for Allison Abney American Society for Bone and Mineral Research Principal Investigator
TRI KL2 Scholars award - Ashby UAMS College of Medicine Principal Investigator
ASBMR 2025 Young Investigator Travel Grant for Sudip Panday (Sato-Mentor) American Society for Bone and Mineral Research Principal Investigator
Glucocorticoid-induced Atrophy in Bone and Muscle NIH Co-Investigator