Analiz Rodriguez
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Associate Professor
Also affiliated: Kanazawa University (2020); Atrium Health Wake Forest Baptist (2014–2016); City Of Hope National Medical Center (2017–2022); Los Alamos National Laboratory (2004); University of Idaho (2007); University of Arkansas Medical Center (2019–2024); Cancer Institute (WIA) (2019); Oxford University Press (United Kingdom) (2020); University Medical Center (2016); New College of Florida (2004); City of Hope (2017–2022); Winthrop Rockefeller Foundation (2019–2023); Ministry of Construction and Physical Planning (2010); Neurological Surgery (2020–2022); Arkansas Department of Health (2020); Beckman Research Institute (2022); Wake Forest University (2014–2017); University of Colorado Anschutz Medical Campus (2017); Case Western Reserve University (2007–2009); Stony Brook University (2020); University of Colorado Denver (2017); Icahn School of Medicine at Mount Sinai (2017)
Faculty Researcher
Neurosurgery, College of Medicine
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Analiz Rodriguez investigates novel therapeutic strategies for glioblastoma, a highly aggressive brain tumor. Her work includes the development and evaluation of oncolytic virotherapy, such as the DNX-2401 virus, in combination with immunotherapies like pembrolizumab for recurrent glioblastoma. Rodriguez also explores the potential of CAR-T cell therapies, examining their application in solid tumors and specifically for glioblastoma, including the development of "off-the-shelf" steroid-resistant CAR T cells targeting IL13Rα2.
Her research also encompasses the creation of advanced preclinical models to better understand tumor biology and predict treatment responses. This includes utilizing zebrafish cancer avatars to analyze tumor heterogeneity and patient outcomes, as well as developing functional precision medicine pipelines that combine comparative transcriptomics and tumor organoid modeling. She has received funding from the NIH/National Cancer Institute for the development of immunocompetent melanoma brain metastases organoids. Rodriguez is a highly cited researcher with an h-index of 26 and over 180 publications.
Metrics
- h-index: 26
- Publications: 183
- Citations: 7,899
Selected Publications
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Longitudinal multi-omics characterization of the malignant evolution in multirelapsing glioblastoma (2026)
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Long-read sequencing for cancer liquid biopsy: advancing precision oncology (2026)
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Endoscopic transsphenoidal resection of large sellar chondrosarcoma compressing the optic nerve: illustrative case (2026)
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ANGI-14. GLIOBLASTOMA PROGRESSION FROM TRANSCRIPTOMIC REGULATION TO BRAIN FUNCTIONAL CONNECTIVITY (2025)
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RADT-51. SURGICALLY TARGETED RADIATION THERAPY (START) FOR PREVIOUSLY IRRADIATED RECURRENT BRAIN METASTASES: INITIAL REPORT FROM A MULTI-INSTITUTIONAL PROSPECTIVE STUDY (2025)
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Laser Interstitial Thermal Therapy for Brain Tumors: a Prospective Multicenter Analysis of 787 Patients from the LAANTERN Study (2025)
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Survival Outcomes of Immune Checkpoint Inhibitors in Conjunction with Cranial Radiation for Older Adults with Non-Small Cell Lung Cancer and Synchronous Brain Metastasis (2025)
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Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial (2025)
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Interstitial Thermal Therapy in Mesial Temporal Lobe Epilepsy (2025)
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Navigating molecular neuropathology of CNS neoplasms for the practicing surgical pathologist (2025)
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Abstract 2645: Rnd3 depletion in lung cancer cell lines decreases cell invasion and migration in a ROCK1 independent manner (2025)
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SURG-54. RECURRENT BRAIN METASTASES (RBM) TREATED WITH SURGICALLY TARGETED RADIATION THERAPY (START): PRELIMINARY SAFETY EVALUATION FROM A MULTI-INSTITUTIONAL PROSPECTIVE REGISTRY (2024)
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Toward standardized brain tumor tissue processing protocols in neuro-oncology: a perspective for gliomas and beyond (2024)
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Functional prediction of response to therapy prior to therapeutic intervention is associated with improved survival in patients with high-grade glioma (2024)
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Functional precision medicine assay for recurrent meningioma: a proof of principle. Illustrative case (2024)
Federal Grants 1 $76,500 total
Development of immunocompetent melanoma brain metastases organoids
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- A Phase IlI Clinical Trial Evaluating DCVax-L, Autologous Dendritis Cells Pulsed Northwest Biotherapeutics, Inc. Principal Investigator
- Photobiomodulation to Ameliorate Neuronal Degeneration and Cognitive Decline after Mixed Field Irradiation - Continuation National Aeronautics & Space Administration Co-Investigator
- Center for Studies of Host Response to Cancer Therapy NIH Co-Investigator
- Novel Platform linking cancer-specific glycosylation with cell signaling outcomes NIH Co-Investigator
Collaboration Network
Top Collaborators
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion
- Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon
- Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma
- Genomic and Transcriptomic Profiling of Brain Metastases
Showing 5 of 7 shared publications
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon
- Genomic and Transcriptomic Profiling of Brain Metastases
- Primary glioblastoma of the cauda equina with molecular and histopathological characterization: Case report
- SMARCA4-deficient central nervous system metastases: A case series and systematic review
Showing 5 of 7 shared publications
- CAR-T Therapies in Solid Tumors: Opportunities and Challenges
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- CAR T-cells to treat brain tumors
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- DNA Polymerase Kappa Acts as a Barrier to Unrestrained Replication in Glioblastoma
Showing 5 of 7 shared publications
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- DNA Polymerase Kappa Acts as a Barrier to Unrestrained Replication in Glioblastoma
- 323 Generation of a functional precision medicine pipeline which combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma
Showing 5 of 6 shared publications
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Genomic and Transcriptomic Profiling of Brain Metastases
- Primary glioblastoma of the cauda equina with molecular and histopathological characterization: Case report
- Long-read sequencing for brain tumors
- 323 Generation of a functional precision medicine pipeline which combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma
- Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion
- Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon
- Genomic and Transcriptomic Profiling of Brain Metastases
- 1211 Defining the role of PCK2 in T cell metabolic plasticity in Glioblastoma
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion
- Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon
- Genomic and Transcriptomic Profiling of Brain Metastases
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- Genomic and Transcriptomic Profiling of Brain Metastases
- Synthesis and Anti‐Melanoma Activity of Acryloyl Pyridinone Analogues
- Monensin and its analogues show anti‐glioblastoma activity in an organoid model of cancer
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Machine learning multi-omics analysis reveals cancer driver dysregulation in pan-cancer cell lines compared to primary tumors
- Long-read sequencing for brain tumors
- 323 Generation of a functional precision medicine pipeline which combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma
- Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators
- Laser interstitial thermal therapy for new and recurrent meningioma: a prospective and retrospective case series
- Interstitial Thermal Therapy in Mesial Temporal Lobe Epilepsy
- Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators
- Laser interstitial thermal therapy for new and recurrent meningioma: a prospective and retrospective case series
- Interstitial Thermal Therapy in Mesial Temporal Lobe Epilepsy
- An Examination of Patients and Caregivers on Reddit Navigating Brain Cancer: Content Analysis of the Brain Tumor Subreddit
- Pulsed reduced dose-rate radiotherapy for previously irradiated tumors in the brain and spine
- QOLP-26. ANALYSIS OF REDDIT USERS' PERSPECTIVES OF BRAIN TUMORS
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Machine learning multi-omics analysis reveals cancer driver dysregulation in pan-cancer cell lines compared to primary tumors
- 323 Generation of a functional precision medicine pipeline which combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Machine learning multi-omics analysis reveals cancer driver dysregulation in pan-cancer cell lines compared to primary tumors
- 323 Generation of a functional precision medicine pipeline which combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- 323 Generation of a functional precision medicine pipeline which combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma
- Clinical application of a functional 3D ex vivo test to predict therapeutic response in patients with HGG: A progression-free survival analysis.
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