Analiz Rodriguez Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Associate Professor
faculty
Neurosurgery, College of Medicine
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Analiz Rodriguez, an Associate Professor in Neurosurgery at the University of Arkansas, studies glioblastoma and other brain tumors. Her research focuses on developing and testing novel therapeutic strategies, including oncolytic virotherapy, CAR-T cell therapies, and precision medicine approaches. She has investigated the efficacy of combining oncolytic DNX-2401 virotherapy with pembrolizumab in recurrent glioblastoma, as detailed in a phase 1/2 trial. Her work also explores the potential of off-the-shelf, CAR T-cells engineered to target IL13Rα2 for glioblastoma treatment.
Dr. Rodriguez utilizes advanced models to understand tumor biology and predict treatment outcomes. This includes functional precision medicine pipelines that combine comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies. She also investigates zebrafish cancer avatars as a translational platform for analyzing tumor heterogeneity. Her research has led to publications on the anti-glioblastoma activity of monensin and its analogs in organoid models, as well as the utility of biobanked patient-derived organoids for studying cancer invasion. She has a publication record of 182 papers with 7,562 citations and an h-index of 26. Dr. Rodriguez has served as a Co-PI on an NSF grant totaling $75,000.
Metrics
- h-index: 26
- Publications: 181
- Citations: 7,670
Selected Publications
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Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial (2025)
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Interstitial Thermal Therapy in Mesial Temporal Lobe Epilepsy (2025)
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Toward standardized brain tumor tissue processing protocols in neuro-oncology: a perspective for gliomas and beyond (2024)
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Functional prediction of response to therapy prior to therapeutic intervention is associated with improved survival in patients with high-grade glioma (2024)
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Functional precision medicine assay for recurrent meningioma: a proof of principle. Illustrative case (2024)
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Immune checkpoint inhibitors as subsequent treatment in older adults with non-small cell lung cancer and synchronous brain metastases (2024)
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Long-read sequencing for brain tumors (2024)
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SMARCA4-deficient central nervous system metastases: A case series and systematic review (2024)
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Laser interstitial thermal therapy for new and recurrent meningioma: a prospective and retrospective case series (2024)
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Synthesis and Anti‐Melanoma Activity of Acryloyl Pyridinone Analogues (2023)
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CTIM-19. ONCOLYTIC DNX-2401 VIROTHERAPY PLUS PEMBROLIZUMAB IN RECURRENT GLIOBLASTOMA: A PHASE 1/2 TRIAL (2023)
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1211 Defining the role of PCK2 in T cell metabolic plasticity in Glioblastoma (2023)
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Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma (2023)
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Real-World Survival of First-Line Immune Checkpoint Inhibitor Treatment Versus Chemotherapy in Older Patients With Non–Small-Cell Lung Cancer and Synchronous Brain Metastases (2023)
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Using the Chick Embryo Brain as a Model for <em>In Vivo</em> and <em>Ex Vivo</em> Analyses of Human Glioblastoma Cell Behavior (2023)
Federal Grants 1 $75,000 total
Grants & Funding
- A Phase IlI Clinical Trial Evaluating DCVax-L, Autologous Dendritis Cells Pulsed Northwest Biotherapeutics, Inc. Principal Investigator
- Development of immunocompetent melanoma brain metastases organoids NIH/Nat. Cancer Institute Principal Investigator
- A Phase IlI Clinical Trial Evaluating DCVax-L, Autologous Dendritis Cells Pulsed Northwest Biotherapeutics, Inc. Principal Investigator
- Development of immunocompetent melanoma brain metastases organoids NIH/Nat. Cancer Institute Principal Investigator
- No FP attached UAMS Internal Research Awards Principal Investigator
- Photobiomodulation to Ameliorate Neuronal Degeneration and Cognitive Decline after Mixed Field Irradiation - Continuation National Aeronautics & Space Administration Co-Investigator
- Center for Studies of Host Response to Cancer Therapy NIH Co-Investigator
- Novel Platform linking cancer-specific glycosylation with cell signaling outcomes NIH Co-Investigator
Collaboration Network
Top Collaborators
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon
- Genomic and Transcriptomic Profiling of Brain Metastases
- Primary glioblastoma of the cauda equina with molecular and histopathological characterization: Case report
- SMARCA4-deficient central nervous system metastases: A case series and systematic review
Showing 5 of 9 shared publications
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion
- Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon
- Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma
- Genomic and Transcriptomic Profiling of Brain Metastases
Showing 5 of 7 shared publications
- CAR-T Therapies in Solid Tumors: Opportunities and Challenges
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- CAR T-cells to treat brain tumors
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- DNA Polymerase Kappa Acts as a Barrier to Unrestrained Replication in Glioblastoma
Showing 5 of 7 shared publications
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- DNA Polymerase Kappa Acts as a Barrier to Unrestrained Replication in Glioblastoma
- 323 Generation of a functional precision medicine pipeline which combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma
Showing 5 of 6 shared publications
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Genomic and Transcriptomic Profiling of Brain Metastases
- Primary glioblastoma of the cauda equina with molecular and histopathological characterization: Case report
- Long-read sequencing for brain tumors
- 323 Generation of a functional precision medicine pipeline which combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma
- Toward standardized brain tumor tissue processing protocols in neuro-oncology: a perspective for gliomas and beyond
- Operative planning for a functional precision medicine assay of recurrent high-grade glioma: illustrative case
- A rare case of atypical intradural extramedullary glioblastoma diagnosed utilizing next-generation sequencing and methylation profiling: illustrative case
- Long-read sequencing for brain tumors
- Functional precision medicine assay for recurrent meningioma: a proof of principle. Illustrative case
- SMARCA4-deficient central nervous system metastases: A case series and systematic review
- Operative planning for a functional precision medicine assay of recurrent high-grade glioma: illustrative case
- A rare case of atypical intradural extramedullary glioblastoma diagnosed utilizing next-generation sequencing and methylation profiling: illustrative case
- Long-read sequencing for brain tumors
- Functional precision medicine assay for recurrent meningioma: a proof of principle. Illustrative case
- Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion
- Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon
- Genomic and Transcriptomic Profiling of Brain Metastases
- 1211 Defining the role of PCK2 in T cell metabolic plasticity in Glioblastoma
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion
- Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon
- Genomic and Transcriptomic Profiling of Brain Metastases
- An Examination of Patients and Caregivers on Reddit Navigating Brain Cancer: Content Analysis of the Brain Tumor Subreddit
- Pulsed reduced dose-rate radiotherapy for previously irradiated tumors in the brain and spine
- QOLP-26. ANALYSIS OF REDDIT USERS' PERSPECTIVES OF BRAIN TUMORS
- An Examination of Patients and Caregivers on Reddit Navigating Brain Cancer: Content Analysis of the Brain Tumor Subreddit (Preprint)
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- Genomic and Transcriptomic Profiling of Brain Metastases
- Synthesis and Anti‐Melanoma Activity of Acryloyl Pyridinone Analogues
- Monensin and its analogues show anti‐glioblastoma activity in an organoid model of cancer
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- 323 Generation of a functional precision medicine pipeline which combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma
- Clinical application of a functional 3D ex vivo test to predict therapeutic response in patients with HGG: A progression-free survival analysis.
- INNV-33. FUNCTIONAL EX VIVO TESTING PROSPECTIVELY IDENTIFIES NEWLY DIAGNOSED GLIOBLASTOMA PATIENTS SENSITIVE TO TEMOZOLOMIDE TREATMENT IRRESPECTIVE OF MGMT METHYLATION STATUS
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma
- Machine learning multi-omics analysis reveals cancer driver dysregulation in pan-cancer cell lines compared to primary tumors
- Long-read sequencing for brain tumors
- 323 Generation of a functional precision medicine pipeline which combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma
- An Examination of Patients and Caregivers on Reddit Navigating Brain Cancer: Content Analysis of the Brain Tumor Subreddit
- Treatment Trends and Inpatient Mortality in Isolated Severe Traumatic Brain Injury Using the National Trauma Data Bank
- QOLP-26. ANALYSIS OF REDDIT USERS' PERSPECTIVES OF BRAIN TUMORS
- An Examination of Patients and Caregivers on Reddit Navigating Brain Cancer: Content Analysis of the Brain Tumor Subreddit (Preprint)
- Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon
- Surgical Relevance of the Suprameatal Tubercle During Superior Petrosal Vein-Sparing Trigeminal Nerve Microvascular Decompression
- Basilar decompression via a far lateral transcondylar approach: technical note
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