Annick De Loose

Researcher

UAMS

Last publication 2024 Last refreshed 2026-05-16

faculty

6 h-index 67 pubs 131 cited

Research Areas

Links

ORCID Lab Website

OverviewAI-generated summary

Annick De Loose's research focuses on the development and application of precision medicine strategies, particularly for brain tumors. Her work involves creating functional pipelines that integrate comparative transcriptomics and tumor organoid modeling to identify personalized treatment approaches for glioblastoma. De Loose also investigates the utility of biobanked patient-derived organoids as models for studying cancer invasion and for testing therapeutic interventions. Her publications include work on the synthesis and anti-melanoma activity of acryloyl pyridinone analogues and the identification of NEK2 as a therapeutic target in lymphoma. De Loose has published 67 papers, with an h-index of 6 and 129 total citations. She has collaborated extensively with Vijay Patel, Sydnye L. Shuttleworth, Ying-Zhi Xu, and Mason McCrury, all from the University of Arkansas for Medical Sciences, with 43 shared publications among them.

Metrics

h-index: 6
Publications: 67
Citations: 131

Selected Publications

Synthesis and Anti‐Melanoma Activity of Acryloyl Pyridinone Analogues (2023)

1 citation DOI OpenAlex
Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma (2023)

13 citations DOI OpenAlex
323 Generation of a functional precision medicine pipeline which combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma (2022)

DOI OpenAlex
A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma (2021)

27 citations DOI OpenAlex
Genomic and Transcriptomic Profiling of Brain Metastases (2021)

7 citations DOI OpenAlex
Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion (2021)

23 citations DOI OpenAlex
Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon (2021)

14 citations DOI OpenAlex