Annick De Loose

Researcher

University of Arkansas for Medical Sciences

faculty

6 h-index 67 pubs 125 cited

Research Areas

Cancer Treatment and Pharmacology Cancer Genomics and Diagnostics Neurological disorders and treatments Molecular Biology Techniques and Applications Cancer-related molecular mechanisms research Bioinformatics and Genomic Networks

Links

ORCID Lab Website

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OverviewAI-generated summary

Annick De Loose's research focuses on developing and applying precision medicine approaches for cancer treatment, particularly glioblastoma and lymphoma. She has investigated the use of tumor organoids derived from patient samples as models to study treatment strategies and the inhibition of cancer cell invasion. Her work has also identified NEK2 as a potential therapeutic target in lymphoma, exploring bifunctional inhibitors to regulate oncogenic pathways.

De Loose has contributed to the development of brain tumor biobanks, emphasizing the role of neurosurgeons in this process. Her publications also include studies on the genomic and transcriptomic profiling of brain metastases and the synthesis and anti-melanoma activity of novel compounds. She has a history of active collaboration with researchers at the University of Arkansas for Medical Sciences, including Vijay Patel, Sydnye L. Shuttleworth, Ying-Zhi Xu, and Mason McCrury, with whom she shares numerous publications.

Metrics

  • h-index: 6
  • Publications: 67
  • Citations: 125

Selected Publications

  • Synthesis and Anti‐Melanoma Activity of Acryloyl Pyridinone Analogues (2023) DOI
  • 323 Generation of a functional precision medicine pipeline which combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma (2022) DOI
  • A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma (2021) DOI
  • Genomic and Transcriptomic Profiling of Brain Metastases (2021) DOI
  • Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion (2021) DOI
  • Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon (2021) DOI

Collaborators

Researchers in the database who share publications

Vijay Patel University of Arkansas for Medical Sciences 43 shared publications Sydnye L. Shuttleworth University of Arkansas for Medical Sciences 43 shared publications Ying-Zhi Xu University of Arkansas for Medical Sciences 43 shared publications Mason McCrury University of Arkansas for Medical Sciences 43 shared publications Kennith Swafford University of Arkansas for Medical Sciences 43 shared publications Baku Acharya University of Arkansas for Medical Sciences 41 shared publications Samantha Kendrick University of Arkansas for Medical Sciences 40 shared publications Syed Hassan Mehdi University of Arkansas for Medical Sciences 40 shared publications

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