Murat Gökden

Federal Grant PI High Impact

Professor

University of Arkansas for Medical Sciences

faculty

Pathology, College of Medicine

26 h-index 156 pubs 2,887 cited

Research Areas

Cancer-related molecular mechanisms research Neurological disorders and treatments Genomics and Chromatin Dynamics Epigenetics and DNA Methylation Cancer Genomics and Diagnostics COVID-19 Clinical Research Studies Neuroscience and Neuropharmacology Research Mitochondrial Function and Pathology

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OverviewAI-generated summary

Murat Gökden is a Professor of Pathology at the University of Arkansas for Medical Sciences. His research interests include the molecular diagnostics of central nervous system tumors, functional precision medicine for glioblastoma, and the study of various neurological disorders. He has published extensively on these topics, with recent work focusing on whole-genome DNA methylation profiling for CNS tumors and the development of a precision medicine pipeline for glioblastoma that integrates comparative transcriptomics and tumor organoid modeling.

Gökden's work also extends to understanding specific conditions such as astroblastomas and their relation to radial glia stem cell lineages, as well as investigating the spectrum of hemorrhagic encephalitis in COVID-19 patients and mitochondrial ultrastructural defects in genetic disorders. He is a high-impact researcher, indicated by his h-index of 26 and over 2,800 citations across 156 publications.

His research has been supported by federal grants, including funding from the NIH/National Cancer Institute for his work on Th17-DC immunotherapy for ovarian cancer, and from the NIH/NIH Office of the Director for research into platelets in radiation-induced immune dysregulation. Gökden leads a research group and collaborates with several colleagues at the University of Arkansas for Medical Sciences, including Analiz Rodriguez and J. Stephen Nix.

Research Overview

Academic Appointment • Professor of Pathology Department - Pathology Education • Fellowship: Cytopathology-University of Arkansas for Medical Sciences • Fellowship: Surgical Pathology-University of Texas, MD Anderson Cancer Center • Fellowship: Neuropathology-Washington University in St. Louis • Residency: Anatomic Pathology- Washington University in St. Louis • Medical School: Dokuz Eylul Medical School, Izmir, Turkey Professional Certifications • American Board of Pathology-Anatomic Pathology • American Board of Pathology-Neuropathology • American Board of Pathology-Cytopathology

Metrics

h-index: 26
Publications: 156
Citations: 2,887

Selected Publications

Targeted Inhibition in Pediatric MET and ALK-Altered Hemispheric Gliomas: Objective Responses Followed by Treatment Resistance (2025) DOI
Signal Recognition Particle Myopathy With Cardiac Manifestations in Rheumatoid Arthritis (2025) DOI
Surgery of peritorcular meningiomas: the structural basis for preservation of torcular venous flow (2025) DOI
Navigating molecular neuropathology of CNS neoplasms for the practicing surgical pathologist (2025) DOI
Can Transcutaneous Vagus Nerve Stimulation Be Effective after Rats’ Spinal Cord Injury? (2025) DOI
A rare presentation of pediatric germinoma mimicking optic pathway glioma: illustrative case (2025) DOI
Large B-cell Lymphoma With Interferon Regulatory Factor 4 Rearrangement Presenting as a Primary Central Nervous System Lymphoma in the Brain (2025) DOI
Unusual Presentation and Rare Location of Enterogenous Cyst in the Cerebellopontine Angle: Two Cases and Review of the Literature (2025) DOI
A novel rotation and scale-invariant deep learning framework leveraging conical transformers for precise differentiation between meningioma and solitary fibrous tumor (2025) DOI
Letter to the Editor Regarding “An Extremely Rare Case of Collision Tumor: A Craniopharyngioma Coexists Pilocytic Astrocytoma” (2025) DOI
Unexpected Presentations of Histiocytic Disorders as Mass Lesions in the Central Nervous System and Spine (2024) DOI
Concurrent ependymal and ganglionic differentiation in a subset of supratentorial neuroepithelial tumors with EWSR1-PLAGL1 rearrangement (2024) DOI
Functional precision medicine assay for recurrent meningioma: a proof of principle. Illustrative case (2024) DOI
Long-read sequencing for brain tumors (2024) DOI
SMARCA4-deficient central nervous system metastases: A case series and systematic review (2024) DOI