Biography and Research Information
OverviewAI-generated summary
Giselle Almeida Gonzalez investigates the molecular mechanisms underlying pediatric acute megakaryoblastic leukemia (AML). Her research focuses on how epigenetic alterations, specifically enhancer methylation and MED12L expression, contribute to the disease's progression and resistance to targeted therapies. Almeida Gonzalez has published work examining the role of the CBFA2T3-GLIS2 fusion gene in reprogramming DNA methylation patterns to promote apoptotic resistance in AML. Her scholarly work has involved collaborations with researchers at the University of Arkansas for Medical Sciences, including Samrat Roy Choudhury, Jason E. Farrar, Arundhati Chavan, and Jordan T. Bird. Almeida Gonzalez's publication record includes studies on transcriptional rewiring and epigenetic vulnerabilities in pediatric AML.
Metrics
- h-index: 1
- Publications: 4
- Citations: 5
Selected Publications
-
Abstract 3496: Epigenetic repurposing by CBFA2T3-GLIS2 reveals a druggable DNA methylation axis in high-risk pediatric AML vulnerability in pediatric AML (2026)
-
Abstract PR006: CBFA2T3–GLIS2 fusion reprograms enhancer-linked DNA methylation to enforce apoptotic resistance and defines an epigenetic vulnerability in pediatric AML (2026)
-
Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia (2025)
-
Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors (2021)
Collaboration Network
Top Collaborators
Samrat Roy Choudhury
University of Arkansas for Medical Sciences
3 shared publications
In database
- Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
- Abstract PR006: CBFA2T3–GLIS2 fusion reprograms enhancer-linked DNA methylation to enforce apoptotic resistance and defines an epigenetic vulnerability in pediatric AML
Jason E. Farrar
Arkansas Children's Hospital
3 shared publications
In database
- Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
- Abstract PR006: CBFA2T3–GLIS2 fusion reprograms enhancer-linked DNA methylation to enforce apoptotic resistance and defines an epigenetic vulnerability in pediatric AML
Soheil Meshinchi
Fred Hutch Cancer Center (US)
2 shared publications
- Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
Arundhati Chavan
Arkansas Children's Hospital
2 shared publications
In database
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
- Abstract PR006: CBFA2T3–GLIS2 fusion reprograms enhancer-linked DNA methylation to enforce apoptotic resistance and defines an epigenetic vulnerability in pediatric AML
Jordan T. Bird
University of Arkansas for Medical Sciences (US)
1 shared publication
- Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors
Stephanie D. Byrum
University of Arkansas for Medical Sciences
1 shared publication
In database
- Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors
Dane A. Jester
Arkansas Children's Hospital
1 shared publication
In database
- Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors
Troy Davidson
Arkansas Children's Hospital
1 shared publication
In database
- Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors
David L. Becton
Arkansas Children's Hospital
1 shared publication
In database
- Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors
Jenny L. Smith
Fred Hutch Cancer Center (US)
1 shared publication
- Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors
Rhonda E. Ries
Fred Hutch Cancer Center (US)
1 shared publication
- Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors
Akhilesh Kaushal
Arkansas Children's Hospital
1 shared publication
In database
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
Pritam Biswas
Arkansas Children's Hospital
1 shared publication
In database
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
Cory C. Padilla
Biota Pharmaceuticals (United States) (US)
1 shared publication
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
Jay F. Sarthy
1 shared publication
- Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia
Similar Researchers
Based on overlapping research topics
Arundhati Chavan
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
Epigenetics and DNA Methylation
Child and Adolescent Health
Jason E. Farrar
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
Child and Adolescent Health
Genomics and Chromatin Dynamics
Akhilesh Kaushal
University of Arkansas for Medical Sciences
Epigenetics and DNA Methylation
Child and Adolescent Health
Genomics and Chromatin Dynamics
Nirmeen Elmadany
University of Arkansas for Medical Sciences
Epigenetics and DNA Methylation
Child and Adolescent Health
Bioinformatics and Genomic Networks
H.K. Wong
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
Epigenetics and DNA Methylation
Bioinformatics and Genomic Networks
Samrat Roy Choudhury
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
Epigenetics and DNA Methylation
Genomics and Chromatin Dynamics