Ayesha Arefin
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
Staff fellow Biologist
Formerly Arkansas Affiliated with NCTR through 2023.
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Ayesha Arefin's research focuses on developing and validating novel biological models for drug safety assessment. She investigates the use of liver microphysiological systems, including those co-culturing human primary hepatocytes and nonparenchymal liver cells, to study drug-induced liver injury. Arefin has characterized the reproducibility of these systems for assaying drug toxicity, metabolism, and accumulation. Her work also extends to engineered heart tissue derived from human pluripotent stem cells, assessing the reproducibility of drug-induced effects on tissue contractility. Additionally, her publications include work on fabricating flexible membranes for tissue engineering applications and developing microfluidic methods for testing elastomeric membranes.
Metrics
- h-index: 8
- Publications: 10
- Citations: 214
Positions
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Staff fellow Biologist 2021–presentNational Center for Toxicological Research Department of Systems Biology ORCID
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Graduate Research Assistant 2011–presentLos Alamos National Laboratory B-10: Biosecurity and Public Health ORCID
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US Food and Drug Administration 2018–2022ORCID
Selected Publications
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Reproducibility of drug-induced effects on the contractility of an engineered heart tissue derived from human pluripotent stem cells (2023)
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Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury (2022)
Collaboration Network
Top Collaborators
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Reproducibility of drug-induced effects on the contractility of an engineered heart tissue derived from human pluripotent stem cells
- Reproducibility of drug-induced effects on the contractility of an engineered heart tissue derived from human pluripotent stem cells
- Reproducibility of drug-induced effects on the contractility of an engineered heart tissue derived from human pluripotent stem cells
- Reproducibility of drug-induced effects on the contractility of an engineered heart tissue derived from human pluripotent stem cells
- Reproducibility of drug-induced effects on the contractility of an engineered heart tissue derived from human pluripotent stem cells
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