Match tier Likely match
Presence Formerly Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-10-05

Ayesha Arefin

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Staff fellow Biologist

Formerly Arkansas Affiliated with NCTR through 2023.

8 h-index 10 pubs 214 cited

  • Humans
  • Hepatocytes
  • Lab-On-A-Chip Devices
  • Acetaminophen
  • Chemical and Drug Induced Liver Injury
  • Tissue Engineering
  • Cells, Cultured
  • Drug Evaluation, Preclinical
  • Liver
  • Models, Biological
  • Reproducibility of Results
  • Toxicity Tests
  • Spheroids, Cellular
  • Cytochrome P-450 CYP3A
  • Primary Cell Culture

Biography and Research Information

OverviewAI-generated summary

Ayesha Arefin's research focuses on developing and validating novel biological models for drug safety assessment. She investigates the use of liver microphysiological systems, including those co-culturing human primary hepatocytes and nonparenchymal liver cells, to study drug-induced liver injury. Arefin has characterized the reproducibility of these systems for assaying drug toxicity, metabolism, and accumulation. Her work also extends to engineered heart tissue derived from human pluripotent stem cells, assessing the reproducibility of drug-induced effects on tissue contractility. Additionally, her publications include work on fabricating flexible membranes for tissue engineering applications and developing microfluidic methods for testing elastomeric membranes.

Metrics

  • h-index: 8
  • Publications: 10
  • Citations: 214

Positions

  • Staff fellow Biologist 2021–present
    National Center for Toxicological Research Department of Systems Biology ORCID
  • Graduate Research Assistant 2011–present
    Los Alamos National Laboratory B-10: Biosecurity and Public Health ORCID
  • US Food and Drug Administration 2018–2022
    ORCID

Selected Publications

  • Reproducibility of drug-induced effects on the contractility of an engineered heart tissue derived from human pluripotent stem cells (2023)
    Frontiers in Pharmacology 20 citations DOI OpenAlex
  • Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury (2022)
    Current Protocols 34 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

15 Collaborators 4 Institutions 1 Country

Top Collaborators

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