Match tier
Likely match
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-08-08
D
Dayton M. Petibone
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
Researcher
Also affiliated: United States Food and Drug Administration (2011–2025); Wayne State University (2007–2010)
Faculty Researcher
14 h-index
33 pubs
785 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Dayton M. Petibone's research investigates genotoxicity and carcinogenic outcomes. This work includes evaluating the potential value of animal microphysiological systems for drug development and assessing whether available data are sufficient to inform risk assessment for DNA-reactive drugs. Publications also explore the in vitro effects of compounds like cannabidiol and black cohosh extract on mammalian cells, examining potential genotoxic mechanisms.
Petibone's scholarship includes 33 publications, with 771 citations and an h-index of 14. Key collaborators include Donna L. Mendrick, Volodymyr Tryndyak, Nan Mei, and Mugimane G. Manjanatha, all affiliated with the National Center for Toxicological Research. Recent work has focused on considerations for animal microphysiological systems in drug development, aligning with the 3Rs principles (Replacement, Reduction, Refinement) in animal research.
Metrics
- h-index: 14
- Publications: 33
- Citations: 785
Selected Publications
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Assessing carcinogenic outcomes following short-term exposure to potentially DNA-reactive drugs: Are available data sufficient to inform risk assessment? (2025)
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Considerations from the pharmaceutical industry (IQ MPS affiliate) workshop on animal microphysiological systems and 3Rs in drug development (2025)
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Potential value of animal microphysiological systems (2024)
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In vitro effects of cannabidiol and its main metabolites in mouse and human Sertoli cells (2021)
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Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells (2021)
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Performance of HepaRG and HepG2 cells in the high-throughput micronucleus assay for in vitro genotoxicity assessment (2020)
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Dr. Daniel Acosta and In Vitro toxicology at the U.S. Food and Drug Administration's National Center for Toxicological Research (2019)
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Quantification of cellular associated graphene and induced surface receptor responses (2019)
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Analysis of mutation in the rat <i>Pig‐a</i> assay: I) studies with bone marrow erythroid cells (2018)
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Analysis of mutation in the rat <i>Pig‐a</i> assay: II. Studies with bone marrow granulocytes (2018)
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Fluorescence In Situ Hybridization in Genotoxicity Testing (2017)
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In Vivo Rat T-Lymphocyte Pig-a Assay: Detection and Expansion of Cells Deficient in the GPI-Anchored CD48 Surface Marker for Analysis of Mutation in the Endogenous Pig-a Gene (2017)
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<i>p53</i>‐competent cells and <i>p53</i>‐deficient cells display different susceptibility to oxygen functionalized graphene cytotoxicity and genotoxicity (2017)
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Autophagy function and its relationship to pathology, clinical applications, drug metabolism and toxicity (2016)
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The role of surface chemistry in the cytotoxicity profile of graphene (2016)
Collaboration Network
Top Collaborators
Xilin Li
National Center for Toxicological Research
2 shared publications
In database
- In vitro effects of cannabidiol and its main metabolites in mouse and human Sertoli cells
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Paul C. Brown
Center for Drug Evaluation and Research (US)
2 shared publications
- Potential value of animal microphysiological systems
- Considerations from the pharmaceutical industry (IQ MPS affiliate) workshop on animal microphysiological systems and 3Rs in drug development
Kevin A. Ford
2 shared publications
- Potential value of animal microphysiological systems
- Considerations from the pharmaceutical industry (IQ MPS affiliate) workshop on animal microphysiological systems and 3Rs in drug development
Donna L. Mendrick
United States Food and Drug Administration
2 shared publications
In database
- Potential value of animal microphysiological systems
- Considerations from the pharmaceutical industry (IQ MPS affiliate) workshop on animal microphysiological systems and 3Rs in drug development
Ji‐Eun Seo
National Center for Toxicological Research
1 shared publication
In database
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Xiaoqing Guo
National Center for Toxicological Research
1 shared publication
In database
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Sharon D. Shelton
National Center for Toxicological Research
1 shared publication
In database
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Ying Chen
National Center for Toxicological Research (US)
1 shared publication
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Volodymyr Tryndyak
National Center for Toxicological Research
1 shared publication
In database
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Stephanie L. Smith‐Roe
National Institute of Environmental Health Sciences (US)
1 shared publication
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Kristine L. Witt
National Institute of Environmental Health Sciences (US)
1 shared publication
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Nan Mei
National Center for Toxicological Research
1 shared publication
In database
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Mugimane G. Manjanatha
National Center for Toxicological Research
1 shared publication
In database
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Yuxi Li
United States Food and Drug Administration
1 shared publication
In database
- In vitro effects of cannabidiol and its main metabolites in mouse and human Sertoli cells
Qiangen Wu
United States Food and Drug Administration
1 shared publication
In database
- In vitro effects of cannabidiol and its main metabolites in mouse and human Sertoli cells
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