D
Dayton M. Petibone Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
faculty
14 h-index
33 pubs
775 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Dayton M. Petibone's research investigates genotoxicity and carcinogenic outcomes. This work includes evaluating the potential value of animal microphysiological systems for drug development and assessing whether available data are sufficient to inform risk assessment for DNA-reactive drugs. Publications also explore the in vitro effects of compounds like cannabidiol and black cohosh extract on mammalian cells, examining potential genotoxic mechanisms.
Petibone's scholarship includes 33 publications, with 771 citations and an h-index of 14. Key collaborators include Donna L. Mendrick, Volodymyr Tryndyak, Nan Mei, and Mugimane G. Manjanatha, all affiliated with the National Center for Toxicological Research. Recent work has focused on considerations for animal microphysiological systems in drug development, aligning with the 3Rs principles (Replacement, Reduction, Refinement) in animal research.
Metrics
- h-index: 14
- Publications: 33
- Citations: 775
Selected Publications
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Assessing carcinogenic outcomes following short-term exposure to potentially DNA-reactive drugs: Are available data sufficient to inform risk assessment? (2025)
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Considerations from the pharmaceutical industry (IQ MPS affiliate) workshop on animal microphysiological systems and 3Rs in drug development (2025)
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Potential value of animal microphysiological systems (2024)
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In vitro effects of cannabidiol and its main metabolites in mouse and human Sertoli cells (2021)
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Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells (2021)
Collaboration Network
Top Collaborators
Xilin Li
National Center for Toxicological Research (US)
2 shared publications
- In vitro effects of cannabidiol and its main metabolites in mouse and human Sertoli cells
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Paul C. Brown
Center for Drug Evaluation and Research (US)
2 shared publications
- Potential value of animal microphysiological systems
- Considerations from the pharmaceutical industry (IQ MPS affiliate) workshop on animal microphysiological systems and 3Rs in drug development
Kevin A. Ford
2 shared publications
- Potential value of animal microphysiological systems
- Considerations from the pharmaceutical industry (IQ MPS affiliate) workshop on animal microphysiological systems and 3Rs in drug development
Donna L. Mendrick
United States Food and Drug Administration
2 shared publications
In database
- Potential value of animal microphysiological systems
- Considerations from the pharmaceutical industry (IQ MPS affiliate) workshop on animal microphysiological systems and 3Rs in drug development
Ji‐Eun Seo
National Center for Toxicological Research
1 shared publication
In database
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Xiaoqing Guo
National Center for Toxicological Research
1 shared publication
In database
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Sharon D. Shelton
National Center for Toxicological Research
1 shared publication
In database
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Ying Chen
National Center for Toxicological Research (US)
1 shared publication
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Volodymyr Tryndyak
National Center for Toxicological Research
1 shared publication
In database
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Stephanie L. Smith‐Roe
National Institute of Environmental Health Sciences (US)
1 shared publication
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Kristine L. Witt
National Institute of Environmental Health Sciences (US)
1 shared publication
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Nan Mei
National Center for Toxicological Research
1 shared publication
In database
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Mugimane G. Manjanatha
National Center for Toxicological Research
1 shared publication
In database
- Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Yuxi Li
United States Food and Drug Administration (US)
1 shared publication
- In vitro effects of cannabidiol and its main metabolites in mouse and human Sertoli cells
Qiangen Wu
United States Food and Drug Administration
1 shared publication
In database
- In vitro effects of cannabidiol and its main metabolites in mouse and human Sertoli cells
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