Lijun Ren Data-verified

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Researcher

NCTR

Last publication 2025 Last refreshed 2026-05-09

faculty

24 h-index 86 pubs 1,846 cited

Research Areas

Links

ORCID Research Group

OverviewAI-generated summary

Lijun Ren's research focuses on understanding the biological mechanisms underlying various health conditions and the impact of environmental factors. Ren has investigated the role of Pyruvate Kinase M2 in keratinocyte proliferation, a process relevant to psoriasis. Additionally, Ren's work has explored the use of co-cultures of human primary hepatocytes and nonparenchymal liver cells in a liver-chip model for studying drug-induced liver injury.

Further research by Ren has examined environmental management strategies in response to COVID-19 in China, utilizing text mining of government information, and stakeholder views on plastic restriction policies. Ren also studied the relationship between ozone precursors and control strategies in a Chinese city, and changes in the pathogenic spectrum of acute respiratory tract infections during the COVID-19 epidemic in Beijing. The regulation of meiosis and recombination in rice by the E3 ubiquitin ligase DESYNAPSIS1 is another area of Ren's published work. More recently, research has explored how Celastrol alleviates oxidative stress induced by multi-walled carbon nanotubes through the Keap1/Nrf2/HO-1 signaling pathway.

Ren is a highly cited researcher with an h-index of 24 and has co-authored 87 publications. Key collaborators include Katy S Papineau, Laura K. Schnackenberg, Tucker A. Patterson, and Gonçalo Gamboa da Costa, all from the National Center for Toxicological Research. Ren leads a research group and has recently been active in research.

Metrics

h-index: 24
Publications: 86
Citations: 1,846

Selected Publications

Challenges and solutions in measuring commonly used biomarkers for drug-induced liver injury in a liver-on-a-chip platform (2025)

DOI OpenAlex
Toxicity of ubiquitous tire rubber antiozonant N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its transformation product 6PPD-quinone (6PPD-Q) in primary human hepatocytes and liver spheroids (2025)

DOI OpenAlex
Pexidartinib impairs liver mitochondrial functions causing cell death in primary human hepatocytes at clinically relevant concentrations (2025)

2 citations DOI OpenAlex
Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs—a proof-of-concept study with doxorubicin (2024)

3 citations DOI OpenAlex
Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury (2022)

31 citations DOI OpenAlex