Match tier
Likely match
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-06
L
Lijun Ren
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
High Impact
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24 h-index
86 pubs
1,846 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Lijun Ren's research has investigated the effects of various small-molecule kinase inhibitors on isolated rat liver mitochondria. This work contributes to understanding potential toxicological impacts of FDA-approved drugs.
Further research has explored plant science topics, including the role of the SlFSR gene in controlling fruit shelf-life in tomatoes and the Ornithine δ‐aminotransferase gene's criticality for nitrogen reutilization and development in rice. Additionally, Ren has studied the Os SPL gene's regulation of meiotic fate acquisition in rice, contributing to the genetic understanding of plant reproduction.
Ren's research also extends to environmental science, with publications analyzing the environmental impact of corn straw utilization and the concentration of pollutants in the Yangtze River Delta. The researcher has also examined energy consumption and carbon emissions during urbanization in Shandong Province, China. Ren holds a designation as a highly cited researcher and has published 86 total publications with 1,846 citations, maintaining an h-index of 24. Key collaborators at the National Center for Toxicological Research include Laura K. Schnackenberg and Katy S Papineau, with whom Ren has 5 shared publications.
Metrics
- h-index: 24
- Publications: 86
- Citations: 1,846
Selected Publications
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Challenges and solutions in measuring commonly used biomarkers for drug-induced liver injury in a liver-on-a-chip platform (2025)
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Toxicity of ubiquitous tire rubber antiozonant N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its transformation product 6PPD-quinone (6PPD-Q) in primary human hepatocytes and liver spheroids (2025)
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Pexidartinib impairs liver mitochondrial functions causing cell death in primary human hepatocytes at clinically relevant concentrations (2025)
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Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs—a proof-of-concept study with doxorubicin (2024)
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Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury (2022)
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Performance of high-throughput CometChip assay using primary human hepatocytes: a comparison of DNA damage responses with in vitro human hepatoma cell lines (2020)
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Hepatic Transcript Profiles of Cytochrome P450 Genes Predict Sex Differences in Drug Metabolism (2020)
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Recent advances in understanding the hepatotoxicity associated with protein kinase inhibitors (2020)
Collaboration Network
Top Collaborators
Qiang Shi
National Center for Toxicological Research
9 shared publications
In database
- Effects of 31 FDA approved small-molecule kinase inhibitors on isolated rat liver mitochondria
- Cytotoxicity of 34 FDA approved small-molecule kinase inhibitors in primary rat and human hepatocytes
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Performance of high-throughput CometChip assay using primary human hepatocytes: a comparison of DNA damage responses with in vitro human hepatoma cell lines
- Hepatic Transcript Profiles of Cytochrome P450 Genes Predict Sex Differences in Drug Metabolism
Showing 5 of 9 shared publications
Xi Yang
United States Food and Drug Administration (US)
5 shared publications
- Effects of 31 FDA approved small-molecule kinase inhibitors on isolated rat liver mitochondria
- Cytotoxicity of 34 FDA approved small-molecule kinase inhibitors in primary rat and human hepatocytes
- Recent advances in understanding the hepatotoxicity associated with protein kinase inhibitors
- Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs—a proof-of-concept study with doxorubicin
- Pexidartinib impairs liver mitochondrial functions causing cell death in primary human hepatocytes at clinically relevant concentrations
William B. Mattes
National Center for Toxicological Research
5 shared publications
In database
- Effects of 31 FDA approved small-molecule kinase inhibitors on isolated rat liver mitochondria
- Cytotoxicity of 34 FDA approved small-molecule kinase inhibitors in primary rat and human hepatocytes
- Recent advances in understanding the hepatotoxicity associated with protein kinase inhibitors
- Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs—a proof-of-concept study with doxorubicin
- Pexidartinib impairs liver mitochondrial functions causing cell death in primary human hepatocytes at clinically relevant concentrations
Katy S Papineau
National Center for Toxicological Research
5 shared publications
In database
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs—a proof-of-concept study with doxorubicin
- Pexidartinib impairs liver mitochondrial functions causing cell death in primary human hepatocytes at clinically relevant concentrations
- Toxicity of ubiquitous tire rubber antiozonant N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its transformation product 6PPD-quinone (6PPD-Q) in primary human hepatocytes and liver spheroids
- Challenges and solutions in measuring commonly used biomarkers for drug-induced liver injury in a liver-on-a-chip platform
Laura K. Schnackenberg
National Center for Toxicological Research
5 shared publications
In database
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs—a proof-of-concept study with doxorubicin
- Pexidartinib impairs liver mitochondrial functions causing cell death in primary human hepatocytes at clinically relevant concentrations
- Toxicity of ubiquitous tire rubber antiozonant N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its transformation product 6PPD-quinone (6PPD-Q) in primary human hepatocytes and liver spheroids
- Challenges and solutions in measuring commonly used biomarkers for drug-induced liver injury in a liver-on-a-chip platform
Qiangen Wu
National Center for Toxicological Research
3 shared publications
In database
- Effects of 31 FDA approved small-molecule kinase inhibitors on isolated rat liver mitochondria
- Cytotoxicity of 34 FDA approved small-molecule kinase inhibitors in primary rat and human hepatocytes
- Performance of high-throughput CometChip assay using primary human hepatocytes: a comparison of DNA damage responses with in vitro human hepatoma cell lines
James Greenhaw
National Center for Toxicological Research
3 shared publications
In database
- Effects of 31 FDA approved small-molecule kinase inhibitors on isolated rat liver mitochondria
- Cytotoxicity of 34 FDA approved small-molecule kinase inhibitors in primary rat and human hepatocytes
- Hepatic Transcript Profiles of Cytochrome P450 Genes Predict Sex Differences in Drug Metabolism
Matthew Bryant
National Center for Toxicological Research
3 shared publications
In database
- Effects of 31 FDA approved small-molecule kinase inhibitors on isolated rat liver mitochondria
- Cytotoxicity of 34 FDA approved small-molecule kinase inhibitors in primary rat and human hepatocytes
- Performance of high-throughput CometChip assay using primary human hepatocytes: a comparison of DNA damage responses with in vitro human hepatoma cell lines
Matthew White
National Center for Toxicological Research (US)
2 shared publications
- Effects of 31 FDA approved small-molecule kinase inhibitors on isolated rat liver mitochondria
- Cytotoxicity of 34 FDA approved small-molecule kinase inhibitors in primary rat and human hepatocytes
Thomas Papoian
Center for Drug Evaluation and Research (US)
2 shared publications
- Effects of 31 FDA approved small-molecule kinase inhibitors on isolated rat liver mitochondria
- Cytotoxicity of 34 FDA approved small-molecule kinase inhibitors in primary rat and human hepatocytes
Vikrant Vijay
National Center for Toxicological Research
2 shared publications
In database
- Hepatic Transcript Profiles of Cytochrome P450 Genes Predict Sex Differences in Drug Metabolism
- Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs—a proof-of-concept study with doxorubicin
Mark Avigan
United States Food and Drug Administration (US)
2 shared publications
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Challenges and solutions in measuring commonly used biomarkers for drug-induced liver injury in a liver-on-a-chip platform
Lorna Ewart
Emulate (United States) (US)
2 shared publications
- Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury
- Challenges and solutions in measuring commonly used biomarkers for drug-induced liver injury in a liver-on-a-chip platform
Li Pang
National Center for Toxicological Research
2 shared publications
In database
- Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs—a proof-of-concept study with doxorubicin
- Pexidartinib impairs liver mitochondrial functions causing cell death in primary human hepatocytes at clinically relevant concentrations
Gonçalo Gamboa da Costa
National Center for Toxicological Research
2 shared publications
In database
- Toxicity of ubiquitous tire rubber antiozonant N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its transformation product 6PPD-quinone (6PPD-Q) in primary human hepatocytes and liver spheroids
- Challenges and solutions in measuring commonly used biomarkers for drug-induced liver injury in a liver-on-a-chip platform
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