Christian Herzog
Assistant Professor
faculty
Internal Med, College of Medicine
Research Areas
Biography and Research Information
OverviewAI-generated summary
Christian Herzog's research focuses on understanding the molecular mechanisms underlying kidney diseases, particularly membranous nephropathy and acute kidney injury.
His work has identified novel autoantigens and prognostic biomarkers in these conditions. This includes investigating serine protease HTRA1 and TGFBR3-associated proteins as targets in membranous nephropathy, and SOD1 as a biomarker for acute kidney injury following cardiothoracic surgery. Herzog also studies the role of IGFBP-1 in the clinical prognosis and pathophysiology of acute kidney injury.
His research group has also explored the immunological responses to SARS-CoV-2 infection, including the development of ACE2 autoantibodies and the induction of anti-idiotype antibodies in transgenic mouse models following vaccination. Herzog holds a h-index of 31 with 94 total publications and 2,923 total citations. He collaborates with researchers at the University of Arkansas for Medical Sciences, including Joseph H. Holthoff, Yanping Izak Harville, Aaron J. Storey, and J. Craig Forrest.
Metrics
- h-index: 31
- Publications: 94
- Citations: 2,955
Selected Publications
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Proteomic Profiling of Complement Components in Glomerular Disease (2026)
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The role of IGFBP-1 in the clinical prognosis and pathophysiology of acute kidney injury (2025)
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Sequential SARS-CoV-2 mRNA Vaccination Induces Anti-Idiotype (Anti-ACE2) Antibodies in K18 Human ACE2 Transgenic Mice (2025)
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FSGS in an Adult Transplant Recipient Possibly Linked to a New Antibody against WT1 (2024)
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SOD1 is a novel prognostic biomarker of acute kidney injury following cardiothoracic surgery (2023)
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Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry (2023)
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Urine Mass Spectrometry Can Distinguish Prerenal and Intrarenal AKI (2022)
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Minor Antigens in Membranous Nephropathy Identified by Mass Spectrometry (2022)
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Development of ACE2 autoantibodies after SARS-CoV-2 infection (2021)
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Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy (2021)
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Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy (2021)
Grants & Funding
- Pilot: Glomerular biomarkers of progression in IgA nephropathy NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases - Pass Through: University of Pennsylvania Co-Investigator
- Meprin A Metalloproteinase in Acute Kidney Injury NIH Co-Investigator
- A Device for Detection of Acute Kidney Injury NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases - Pass Through: Nephsmart, LLC Principal Investigator
- Factors Associated with Outcomes in Patients on Continuous Dialysis Dialysis Clinic, Inc. Principal Investigator
- A Device for Detection of Acute Kidney Injury NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases - Pass Through: Nephsmart, LLC Principal Investigator
- Development of a Precision Medicine-Based Diagnostic Tool for Membranous Nephropathy NIH/National Institutes of Health - Pass Through: Arkana Laboratories Principal Investigator
Collaboration Network
Top Collaborators
- Development of ACE2 autoantibodies after SARS-CoV-2 infection
- Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
- SOD1 is a novel prognostic biomarker of acute kidney injury following cardiothoracic surgery
Showing 5 of 11 shared publications
- Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
- Minor Antigens in Membranous Nephropathy Identified by Mass Spectrometry
- Proteomic Profiling of Complement Components in Glomerular Disease
- Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
- Minor Antigens in Membranous Nephropathy Identified by Mass Spectrometry
- Proteomic Profiling of Complement Components in Glomerular Disease
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
- Minor Antigens in Membranous Nephropathy Identified by Mass Spectrometry
- Proteomic Profiling of Complement Components in Glomerular Disease
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
- Minor Antigens in Membranous Nephropathy Identified by Mass Spectrometry
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
- Minor Antigens in Membranous Nephropathy Identified by Mass Spectrometry
- SOD1 is a novel prognostic biomarker of acute kidney injury following cardiothoracic surgery
- The role of IGFBP-1 in the clinical prognosis and pathophysiology of acute kidney injury
- Urine Mass Spectrometry Can Distinguish Prerenal and Intrarenal AKI
- SOD1 is a novel prognostic biomarker of acute kidney injury following cardiothoracic surgery
- Sequential SARS-CoV-2 mRNA Vaccination Induces Anti-Idiotype (Anti-ACE2) Antibodies in K18 Human ACE2 Transgenic Mice
- The role of IGFBP-1 in the clinical prognosis and pathophysiology of acute kidney injury
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
- Development of ACE2 autoantibodies after SARS-CoV-2 infection
- Correction: Development of ACE2 autoantibodies after SARS-CoV-2 infection
- Development of ACE2 autoantibodies after SARS-CoV-2 infection
- Correction: Development of ACE2 autoantibodies after SARS-CoV-2 infection
- Development of ACE2 autoantibodies after SARS-CoV-2 infection
- Correction: Development of ACE2 autoantibodies after SARS-CoV-2 infection
- Development of ACE2 autoantibodies after SARS-CoV-2 infection
- Correction: Development of ACE2 autoantibodies after SARS-CoV-2 infection
- Development of ACE2 autoantibodies after SARS-CoV-2 infection
- Correction: Development of ACE2 autoantibodies after SARS-CoV-2 infection
- Development of ACE2 autoantibodies after SARS-CoV-2 infection
- Correction: Development of ACE2 autoantibodies after SARS-CoV-2 infection
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