Christian Herzog
Assistant Professor
Also affiliated: University of North Carolina at Charlotte (1998); Goethe University Frankfurt (2001–2009); Thai Red Cross Society (1999); University of Vienna (1995–1999); Chulalongkorn University (1999); University of Basel (1987–1989); Queen Saovabha Memorial Institute (1999); Medical University of Graz (2021); Robert Koch Institute (2016); Commissariat à l'Énergie Atomique et aux Énergies Alternatives (2003–2009); University Hospital of Basel (1988); Universitätsklinikum des Saarlandes (1994–2002); CEA Paris-Saclay - Etablissement de Fontenay-aux-roses (2003–2009); Central Arkansas Veterans Healthcare System (2007–2025); University Hospital Frankfurt (2004–2007); National Cancer Institute (1999); Vienna Biocenter (1999); Pediatrics and Genetics (2012); John L. McClellan Memorial Veterans Hospital (1997–2000); Direction des Sciences du Vivant (2005); The Ohio State University (2003); University of Amsterdam (2000); Saarland University (1994–2000)
Internal Med, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Christian Herzog's research focuses on understanding the molecular mechanisms underlying kidney diseases, particularly membranous nephropathy and acute kidney injury.
His work has identified novel autoantigens and prognostic biomarkers in these conditions. This includes investigating serine protease HTRA1 and TGFBR3-associated proteins as targets in membranous nephropathy, and SOD1 as a biomarker for acute kidney injury following cardiothoracic surgery. Herzog also studies the role of IGFBP-1 in the clinical prognosis and pathophysiology of acute kidney injury.
His research group has also explored the immunological responses to SARS-CoV-2 infection, including the development of ACE2 autoantibodies and the induction of anti-idiotype antibodies in transgenic mouse models following vaccination. Herzog holds a h-index of 31 with 94 total publications and 2,923 total citations. He collaborates with researchers at the University of Arkansas for Medical Sciences, including Joseph H. Holthoff, Yanping Izak Harville, Aaron J. Storey, and J. Craig Forrest.
Metrics
- h-index: 31
- Publications: 94
- Citations: 3,034
Positions
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Assistant Professor 2009–presentUniversity of Arkansas for Medical Sciences Internal Med, College of Medicine Institutional directory
Selected Publications
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Proteomic Profiling of Complement Components in Glomerular Disease (2026)
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The role of IGFBP-1 in the clinical prognosis and pathophysiology of acute kidney injury (2025)
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Sequential SARS-CoV-2 mRNA Vaccination Induces Anti-Idiotype (Anti-ACE2) Antibodies in K18 Human ACE2 Transgenic Mice (2025)
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FSGS in an Adult Transplant Recipient Possibly Linked to a New Antibody against WT1 (2024)
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SOD1 is a novel prognostic biomarker of acute kidney injury following cardiothoracic surgery (2023)
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Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry (2023)
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Urine Mass Spectrometry Can Distinguish Prerenal and Intrarenal AKI (2022)
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Minor Antigens in Membranous Nephropathy Identified by Mass Spectrometry (2022)
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Development of ACE2 autoantibodies after SARS-CoV-2 infection (2021)
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Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy (2021)
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Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy (2021)
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NCAM1 Is an Autoantigen in Membranous Lupus Nephritis (2020)
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Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis (2020)
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NELL1 is a target antigen in malignancy-associated membranous nephropathy (2020)
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Serum amyloid P deposition is a sensitive and specific feature of membranous-like glomerulopathy with masked IgG kappa deposits (2019)
Grants & Funding
As listed on this researcher's institutional profile.
- Pilot: Glomerular biomarkers of progression in IgA nephropathy NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases via University of Pennsylvania Co-Investigator
- Meprin A Metalloproteinase in Acute Kidney Injury NIH Co-Investigator
- A Device for Detection of Acute Kidney Injury NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases via Nephsmart, LLC Principal Investigator
- Factors Associated with Outcomes in Patients on Continuous Dialysis Dialysis Clinic, Inc. Principal Investigator
- Development of a Precision Medicine-Based Diagnostic Tool for Membranous Nephropathy NIH/National Institutes of Health via Arkana Laboratories Principal Investigator
Collaboration Network
Top Collaborators
- Development of ACE2 autoantibodies after SARS-CoV-2 infection
- NELL1 is a target antigen in malignancy-associated membranous nephropathy
- Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis
- Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
Showing 5 of 14 shared publications
- Meprin A and meprin α generate biologically functional IL-1β from pro-IL-1β
- ADAM10 Is the Major Sheddase Responsible for the Release of Membrane-associated Meprin A
- Role of meprin metalloproteinases in cytokine processing and inflammation
- Role of meprin A in renal tubular epithelial cell injury
- Meprin A metalloproteinase and its role in acute kidney injury
Showing 5 of 11 shared publications
- NELL1 is a target antigen in malignancy-associated membranous nephropathy
- Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis
- Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
Showing 5 of 9 shared publications
- NELL1 is a target antigen in malignancy-associated membranous nephropathy
- Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis
- Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
Showing 5 of 9 shared publications
- Meprin A and meprin α generate biologically functional IL-1β from pro-IL-1β
- Generation of biologically active interleukin-1β by meprin B
- ADAM10 Is the Major Sheddase Responsible for the Release of Membrane-associated Meprin A
- Role of meprin metalloproteinases in cytokine processing and inflammation
- Meprin A metalloproteinase and its role in acute kidney injury
Showing 5 of 8 shared publications
- NELL1 is a target antigen in malignancy-associated membranous nephropathy
- Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
- Serum amyloid P deposition is a sensitive and specific feature of membranous-like glomerulopathy with masked IgG kappa deposits
Showing 5 of 7 shared publications
- NELL1 is a target antigen in malignancy-associated membranous nephropathy
- Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
- Serum amyloid P deposition is a sensitive and specific feature of membranous-like glomerulopathy with masked IgG kappa deposits
Showing 5 of 7 shared publications
- NELL1 is a target antigen in malignancy-associated membranous nephropathy
- Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
- NCAM1 Is an Autoantigen in Membranous Lupus Nephritis
Showing 5 of 7 shared publications
- Meprin A and meprin α generate biologically functional IL-1β from pro-IL-1β
- ADAM10 Is the Major Sheddase Responsible for the Release of Membrane-associated Meprin A
- Role of meprin A in renal tubular epithelial cell injury
- Meprin A metalloproteinase and its role in acute kidney injury
- Proteolytic processing and inactivation of CCL2/MCP-1 by meprins
- NELL1 is a target antigen in malignancy-associated membranous nephropathy
- Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis
- Serum amyloid P deposition is a sensitive and specific feature of membranous-like glomerulopathy with masked IgG kappa deposits
- NCAM1 Is an Autoantigen in Membranous Lupus Nephritis
- Meprin A and meprin α generate biologically functional IL-1β from pro-IL-1β
- Actinonin, a meprin A inhibitor, protects the renal microcirculation during sepsis
- Delayed treatment with actinonin, a meprin A inhibitor, protects the renal microcirculation and renal function during sepsis in mice
- Activity of Four Allelic Forms of Glutathione S-Transferase hGSTP1-1 for Diol Epoxides of Polycyclic Aromatic Hydrocarbons
- Structure and Function of Residue 104 and Water Molecules in the Xenobiotic Substrate-Binding Site in Human Glutathione S-Transferase P1-1,
- Location of the epoxide function determines specificity of the allelic variants of human glutathione transferase Pi toward benzo[c]chrysene diol epoxide isomers
- Activity of Four Allelic Forms of Glutathione S-Transferase hGSTP1-1 for Diol Epoxides of Polycyclic Aromatic Hydrocarbons
- Structure and Function of Residue 104 and Water Molecules in the Xenobiotic Substrate-Binding Site in Human Glutathione S-Transferase P1-1,
- Location of the epoxide function determines specificity of the allelic variants of human glutathione transferase Pi toward benzo[c]chrysene diol epoxide isomers
- Serum amyloid P deposition is a sensitive and specific feature of membranous-like glomerulopathy with masked IgG kappa deposits
- NCAM1 Is an Autoantigen in Membranous Lupus Nephritis
- Minor Antigens in Membranous Nephropathy Identified by Mass Spectrometry
- NELL1 is a target antigen in malignancy-associated membranous nephropathy
- Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis
- NCAM1 Is an Autoantigen in Membranous Lupus Nephritis
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