Duah Alkam

Researcher

UAMS

Last publication 2026 Last refreshed 2026-05-23

faculty

11 h-index 31 pubs 482 cited

Research Areas

Links

ORCID Research Group

OverviewAI-generated summary

Duah Alkam's research focuses on understanding disease mechanisms and developing novel therapeutic strategies. Alkam has investigated the epigenetic regulation of gene expression in multiple myeloma, specifically examining the role of integrin β-7 in high-risk cytogenetics subgroups. This work has been supported by publications detailing advancements in multi-omics data integration for cancer research, such as a 2021 study on triple-negative breast cancer. Alkam has also contributed to the development of research platforms, including an ex vivo human precision-cut lung slice model for studying SARS-CoV-2 pathogenesis and antiviral efficacy, as noted in a 2024 publication. Additionally, Alkam's work has touched upon infectious disease, with a 2021 publication exploring virulence factor accumulation in Staphylococcus aureus mutants. Scholarship metrics for Alkam include an h-index of 10 and 29 total publications, with 473 total citations. Key collaborators at the University of Arkansas for Medical Sciences include Charity L. Washam (10 shared publications), Stephanie D. Byrum (7 shared publications), Allen Gies (5 shared publications), and Michael S. Robeson (5 shared publications).

Metrics

h-index: 11
Publications: 31
Citations: 482

Selected Publications

Class A scavenger receptors promote tumor progression and induce a unique macrophage phenotype in a mouse model of spontaneous breast cancer (2026)

DOI OpenAlex
Rare SNP in the HELB gene interferes with RPA interaction and cellular function of HELB (2025)

DOI OpenAlex
IP-to-MS: An Unbiased Workflow for Antigen Profiling (2025)

2 citations DOI OpenAlex
An ex vivo human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy (2024)

9 citations DOI OpenAlex
One-pot method for preparing DNA, RNA, and protein for multiomics analysis (2024)

8 citations DOI OpenAlex
An ex vivo human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy (2023)

3 citations DOI OpenAlex
Proteogenomics Analysis to Identify Acquired Resistance-Specific Alterations in Melanoma PDXs on MAPKi Therapy (2023)

DOI OpenAlex
Expression of integrin β-7 is epigenetically enhanced in multiple myeloma subgroups with high-risk cytogenetics (2023)

14 citations DOI OpenAlex
Repurposing live attenuated trivalent MMR vaccine as cost-effective cancer immunotherapy (2022)

6 citations DOI OpenAlex
Proteogenomics Reference Database Protocol v1 (2022)

DOI OpenAlex
Proteogenomics Reference Database Protocol v1 (2022)

DOI OpenAlex
Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy (2022)

DOI OpenAlex
Is amplification bias consequential in transposon sequencing (TnSeq) assays? A case study with a Staphylococcus aureus TnSeq library subjected to PCR-based and amplification-free enrichment methods (2021)

2 citations DOI OpenAlex
Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer (2021)

16 citations DOI OpenAlex
The Increased Accumulation of Staphylococcus aureus Virulence Factors Is Maximized in a purR Mutant by the Increased Production of SarA and Decreased Production of Extracellular Proteases (2021)

12 citations DOI OpenAlex