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Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-15

Duah Alkam

Researcher

Also affiliated: University of California, Los Angeles (2022); Southwestern Medical Center (2016); Winthrop Rockefeller Foundation (2022–2026); Southwestern Medical Center (2016); The University of Texas Southwestern Medical Center (2016)

Faculty Researcher

11 h-index 31 pubs 508 cited

  • Humans
  • Animals
  • Mice
  • Signal Transduction
  • Brain
  • Mutation
  • Female
  • Immunoprecipitation
  • Profilins
  • Amyotrophic Lateral Sclerosis
  • Disease Models, Animal
  • Mice, Transgenic
  • Mutation, Missense
  • Adult
  • Aged

Biography and Research Information

OverviewAI-generated summary

Duah Alkam's research focuses on understanding disease mechanisms and developing therapeutic strategies, with recent work investigating novel approaches to cancer immunotherapy and pathogenesis. Publications include the repurposing of the MMR vaccine for cancer immunotherapy and the enhancement of immune response in hepatocellular carcinoma using an oncolytic virus and immune checkpoint blockade. Alkam has also explored insights into SARS-CoV-2 pathogenesis and antiviral drug efficacy using a human precision-cut lung slice platform. Other research areas include multi-omics data integration for understanding triple-negative breast cancer and the epigenetic regulation of integrin β-7 in multiple myeloma. Alkam's work also extends to bacterial virulence factor accumulation in *Staphylococcus aureus* mutants. With an h-index of 11 and 31 publications, Alkam has collaborated extensively with researchers at the University of Arkansas for Medical Sciences, including Charity L. Washam, Stephanie D. Byrum, Allen Gies, and Michael S. Robeson.

Metrics

  • h-index: 11
  • Publications: 31
  • Citations: 508

Selected Publications

  • Class A scavenger receptors promote tumor progression and induce a unique macrophage phenotype in a mouse model of spontaneous breast cancer (2026)
    Journal of Leukocyte Biology DOI OpenAlex
  • Rare SNP in the <i>HELB</i> gene interferes with RPA interaction and cellular function of HELB (2025)
    NAR Molecular Medicine DOI OpenAlex
  • IP-to-MS: An Unbiased Workflow for Antigen Profiling (2025)
    Journal of Proteome Research 2 citations DOI OpenAlex
  • An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy (2024)
    Journal of Virology 12 citations DOI OpenAlex
  • One-pot method for preparing DNA, RNA, and protein for multiomics analysis (2024)
    Communications Biology 10 citations DOI OpenAlex
  • An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy (2023)
    bioRxiv (Cold Spring Harbor Laboratory) 3 citations DOI OpenAlex
  • Proteogenomics Analysis to Identify Acquired Resistance-Specific Alterations in Melanoma PDXs on MAPKi Therapy (2023)
    SSRN Electronic Journal DOI OpenAlex
  • Expression of integrin β-7 is epigenetically enhanced in multiple myeloma subgroups with high-risk cytogenetics (2023)
    Clinical Epigenetics 15 citations DOI OpenAlex
  • Repurposing live attenuated trivalent MMR vaccine as cost-effective cancer immunotherapy (2022)
    Frontiers in Oncology 7 citations DOI OpenAlex
  • Proteogenomics Reference Database Protocol v1 (2022)
  • Proteogenomics Reference Database Protocol v1 (2022)
  • Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy (2022)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Is amplification bias consequential in transposon sequencing (TnSeq) assays? A case study with a Staphylococcus aureus TnSeq library subjected to PCR-based and amplification-free enrichment methods (2021)
    Microbial Genomics 2 citations DOI OpenAlex
  • Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer (2021)
    Molecular Omics 17 citations DOI OpenAlex
  • The Increased Accumulation of Staphylococcus aureus Virulence Factors Is Maximized in a <i>purR</i> Mutant by the Increased Production of SarA and Decreased Production of Extracellular Proteases (2021)
    Infection and Immunity 12 citations DOI OpenAlex

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Collaboration Network

95 Collaborators 23 Institutions 5 Countries

Top Collaborators

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