Duah Alkam
GPIBS Ph.D. student
Also affiliated: University of California, Los Angeles (2022); University of Arkansas Medical Center (2022–2026); UCLA Jonsson Comprehensive Cancer Center (2022); The University of Texas Southwestern Medical Center (2016)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Duah Alkam's research focuses on understanding disease mechanisms and developing therapeutic strategies, with recent work investigating novel approaches to cancer immunotherapy and pathogenesis. Publications include the repurposing of the MMR vaccine for cancer immunotherapy and the enhancement of immune response in hepatocellular carcinoma using an oncolytic virus and immune checkpoint blockade. Alkam has also explored insights into SARS-CoV-2 pathogenesis and antiviral drug efficacy using a human precision-cut lung slice platform. Other research areas include multi-omics data integration for understanding triple-negative breast cancer and the epigenetic regulation of integrin β-7 in multiple myeloma. Alkam's work also extends to bacterial virulence factor accumulation in *Staphylococcus aureus* mutants. With an h-index of 11 and 31 publications, Alkam has collaborated extensively with researchers at the University of Arkansas for Medical Sciences, including Charity L. Washam, Stephanie D. Byrum, Allen Gies, and Michael S. Robeson.
Metrics
- h-index: 11
- Publications: 31
- Citations: 521
Positions
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GPIBS Ph.D. student publications 2016–2026University of Arkansas for Medical Sciences Institution web page
Selected Publications
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Class A scavenger receptors promote tumor progression and induce a unique macrophage phenotype in a mouse model of spontaneous breast cancer (2026)
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Rare SNP in the HELB gene interferes with RPA interaction and cellular function of HELB (2025)
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IP-to-MS: An Unbiased Workflow for Antigen Profiling (2025)
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An ex vivo human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy (2024)
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One-pot method for preparing DNA, RNA, and protein for multiomics analysis (2024)
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proteoDA: a package for quantitative proteomics (2023)
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An ex vivo human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy (2023)
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Proteogenomics Analysis to Identify Acquired Resistance-Specific Alterations in Melanoma PDXs on MAPKi Therapy (2023)
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Expression of integrin β-7 is epigenetically enhanced in multiple myeloma subgroups with high-risk cytogenetics (2023)
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Repurposing live attenuated trivalent MMR vaccine as cost-effective cancer immunotherapy (2022)
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Proteogenomics Reference Database Protocol v1 (2022)
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Proteogenomics Reference Database Protocol v1 (2022)
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Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy (2022)
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Is amplification bias consequential in transposon sequencing (TnSeq) assays? A case study with a Staphylococcus aureus TnSeq library subjected to PCR-based and amplification-free enrichment methods (2021)
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Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer (2021)
Collaboration Network
Top Collaborators
- proteoDA: a package for quantitative proteomics
- Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer
- Expression of integrin β-7 is epigenetically enhanced in multiple myeloma subgroups with high-risk cytogenetics
- An ex vivo human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy
- One-pot method for preparing DNA, RNA, and protein for multiomics analysis
Showing 5 of 13 shared publications
- proteoDA: a package for quantitative proteomics
- Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer
- One-pot method for preparing DNA, RNA, and protein for multiomics analysis
- Repurposing live attenuated trivalent MMR vaccine as cost-effective cancer immunotherapy
- Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy
Showing 5 of 8 shared publications
- A novel Cas9-targeted long-read assay for simultaneous detection of IDH1/2 mutations and clinically relevant MGMT methylation in fresh biopsies of diffuse glioma
- Genomic characterization of mumps viruses from a large-scale mumps outbreak in Arkansas, 2016
- Three Complete Genome Sequences of Genotype G Mumps Virus from the 2016 Outbreak in Arkansas, USA
- Conservation of Two-Component Signal Transduction Systems in E. coli, Salmonella, and Across 100,000 Bacteria of Various Bacterial Phyla
- Is amplification bias consequential in transposon sequencing (TnSeq) assays? A case study with a Staphylococcus aureus TnSeq library subjected to PCR-based and amplification-free enrichment methods
Showing 5 of 6 shared publications
- A novel Cas9-targeted long-read assay for simultaneous detection of IDH1/2 mutations and clinically relevant MGMT methylation in fresh biopsies of diffuse glioma
- Genomic characterization of mumps viruses from a large-scale mumps outbreak in Arkansas, 2016
- Three Complete Genome Sequences of Genotype G Mumps Virus from the 2016 Outbreak in Arkansas, USA
- Conservation of Two-Component Signal Transduction Systems in E. coli, Salmonella, and Across 100,000 Bacteria of Various Bacterial Phyla
- Is amplification bias consequential in transposon sequencing (TnSeq) assays? A case study with a Staphylococcus aureus TnSeq library subjected to PCR-based and amplification-free enrichment methods
Showing 5 of 6 shared publications
- proteoDA: a package for quantitative proteomics
- Genomic characterization of mumps viruses from a large-scale mumps outbreak in Arkansas, 2016
- Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Reference Database Protocol v1
Showing 5 of 6 shared publications
- A novel Cas9-targeted long-read assay for simultaneous detection of IDH1/2 mutations and clinically relevant MGMT methylation in fresh biopsies of diffuse glioma
- Genomic characterization of mumps viruses from a large-scale mumps outbreak in Arkansas, 2016
- Three Complete Genome Sequences of Genotype G Mumps Virus from the 2016 Outbreak in Arkansas, USA
- Is amplification bias consequential in transposon sequencing (TnSeq) assays? A case study with a Staphylococcus aureus TnSeq library subjected to PCR-based and amplification-free enrichment methods
- PATH-05. RAPID SIMULTANEOUS IDH MUTATION AND MGMT METHYLATION STATUS ASSESSMENT IN GLIOMA PATIENTS USING CRISPR-Cas9-TARGETED NANOPORE SEQUENCING
- A novel Cas9-targeted long-read assay for simultaneous detection of IDH1/2 mutations and clinically relevant MGMT methylation in fresh biopsies of diffuse glioma
- The Increased Accumulation of Staphylococcus aureus Virulence Factors Is Maximized in a purR Mutant by the Increased Production of SarA and Decreased Production of Extracellular Proteases
- Genomic characterization of mumps viruses from a large-scale mumps outbreak in Arkansas, 2016
- Three Complete Genome Sequences of Genotype G Mumps Virus from the 2016 Outbreak in Arkansas, USA
- Is amplification bias consequential in transposon sequencing (TnSeq) assays? A case study with a Staphylococcus aureus TnSeq library subjected to PCR-based and amplification-free enrichment methods
- Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer
- Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Analysis to Identify Acquired Resistance-Specific Alterations in Melanoma PDXs on MAPKi Therapy
- Expression of integrin β-7 is epigenetically enhanced in multiple myeloma subgroups with high-risk cytogenetics
- Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Analysis to Identify Acquired Resistance-Specific Alterations in Melanoma PDXs on MAPKi Therapy
- Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Analysis to Identify Acquired Resistance-Specific Alterations in Melanoma PDXs on MAPKi Therapy
- Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Analysis to Identify Acquired Resistance-Specific Alterations in Melanoma PDXs on MAPKi Therapy
- Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Analysis to Identify Acquired Resistance-Specific Alterations in Melanoma PDXs on MAPKi Therapy
- Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Analysis to Identify Acquired Resistance-Specific Alterations in Melanoma PDXs on MAPKi Therapy
- Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Analysis to Identify Acquired Resistance-Specific Alterations in Melanoma PDXs on MAPKi Therapy
- Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Reference Database Protocol v1
- Proteogenomics Analysis to Identify Acquired Resistance-Specific Alterations in Melanoma PDXs on MAPKi Therapy
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