David P. Douglass
Sourced from institutional research profiles (UAMS TRI or ARA).
Associate Professor
Faculty Researcher
Peds Pediatrics, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
David P. Douglass is an Associate Professor in the Department of Pediatrics at the University of Arkansas for Medical Sciences. His research focuses on the development and validation of prognostic signatures for childhood cancers, particularly neuroblastoma and soft tissue sarcomas. Douglass has investigated the role of pharmacotherapeutic agents and novel agents for treating pediatric non-rhabdomyosarcoma soft tissue sarcomas. His work also includes exploring therapeutic strategies for MYCN-amplified rhabdomyosarcoma and neuroblastoma, such as targeting CDK9. Additionally, he has contributed to understanding clinical features and outcomes for young patients with low-grade non-rhabdomyosarcoma soft tissue sarcomas and has published on rare genetic conditions like Li-Fraumeni syndrome and neonatal tumors with novel fusions. Douglass collaborates with researchers including Kimo C. Stine, Varsha G. Desai, Vikrant Vijay, and James C. Fuscoe.
Metrics
- h-index: 3
- Publications: 12
- Citations: 22
Selected Publications
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Correction: Exploring Predictive Risk Factors for Myocardial Injury in Children Treated with Anthracyclines: A Pilot Study (2026)
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Cancer-associated fibroblasts promote tumor progression in fusion-positive rhabdomyosarcoma (2025)
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Exploring Predictive Risk Factors for Myocardial Injury in Children Treated with Anthracyclines: A Pilot Study (2025)
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Clinical features and outcomes of young patients with low‐grade non‐rhabdomyosarcoma soft tissue sarcomas treated with a risk‐based strategy: A report from Children's Oncology Group study ARST0332 (2024)
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Development and validation of a 21-gene prognostic signature in neuroblastoma (2023)
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Abstract 1558: Targeting CDK9 via the small-molecule inhibitor enitociclib as a therapeutic strategy to treat <i>MYCN</i>-amplified rhabdomyosarcoma and neuroblastoma in children (2023)
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Neonatal osteoblastic tumor with a novel <i>PTBP1::FOSB</i> fusion (2023)
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The Role of Pharmacotherapeutic Agents in Children with Desmoid Tumors (2022)
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A Novel Germline TP53 Mutation in a Patient With Li-Fraumeni Syndrome: Resolving a Variant of Uncertain Significance (2021)
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A NOVEL GERMLINE TP53 MUTATION IN A PATIENT WITH LI-FRAUMENI SYNDROME - RESOLVING A VARIANT OF UNCERTAIN SIGNIFICANCE (2020)
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Primary superficial Ewing sarcoma: A unique entity? A case report including novel findings of <scp><i>ELF3</i></scp> and <scp><i>TNFRSF14</i></scp> copy number loss (2020)
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