Seongok Lee
Post Doctoral Fellow
Also affiliated: Yonsei University (2011); Yonsei University Health System (2011); Catholic University of Korea (2011–2015)
Radiation Oncology, College of Medicine
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Seongok Lee's research focuses on understanding the molecular mechanisms underlying DNA repair and cellular responses to damage. Recent work has investigated the role of histone modifications and associated proteins, such as 53BP1 and RNF168, in regulating homologous recombination and DNA double-strand break repair pathways. Lee has also explored the impact of organ preservation and transplantation on kidney injury and the function of the immunoproteasome in rat kidney allografts. Prior research has examined cephalosporin resistance mechanisms in Escherichia coli and the prevalence of imipenem or meropenem resistance in Klebsiella pneumoniae and Escherichia coli.
Metrics
- h-index: 3
- Publications: 13
- Citations: 33
Positions
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Post Doctoral Fellow publications 2023–2026University of Arkansas for Medical Sciences Radiation Oncology, College of Medicine Institutional directory
Selected Publications
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Heat shock protein 72 is a druggable target during cold storage to improve graft outcome after kidney transplantation (2026)
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137 Protocol optimization for adenine nephropathy in Ahr genotype-divergent mouse strains (2026)
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Complement 5's Role in Mitochondria During Kidney Ischemia-Reperfusion Injury in Rats (2025)
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Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat (2025)
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Mechanism of Impaired Protein Homeostasis in Kidney Grafts Following Cold Storage and Transplantation (Abstract ID: 162640) (2025)
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Ischemia and Reperfusion (IRI)-Induced Kidney Injury Is Attenuated by Complement 5 Gene Deletion (Abstract ID: 161749) (2025)
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Mechanism of Impaired Protein Homeostasis in Kidney Grafts following Cold Storage and Transplant (2024)
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Evolved histone tail regulates 53BP1 recruitment at damaged chromatin (2024)
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Normal Proteasome Function Is Needed to Prevent Kidney Graft Injury during Cold Storage Followed by Transplantation (2024)
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Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function (2024)
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Ischemia-Reperfusion-Mediated Kidney Injury Is Attenuated in a New Complement 5 Knockout Model (2023)
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Cold Storage-Mediated p38MAPK Activation: A Potential Contributor of Proteasome Dysfunction and Kidney Damage After Transplantation (2023)
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Mechanism of Cold Storage-Mediated Regulation of Heat Shock Proteins in Renal Grafts After Transplantation (2023)
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UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair (2023)
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ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination (2022)
Collaboration Network
Top Collaborators
- Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function
- Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat
- Normal Proteasome Function Is Needed to Prevent Kidney Graft Injury during Cold Storage Followed by Transplantation
- Ischemia-Reperfusion-Mediated Kidney Injury Is Attenuated in a New Complement 5 Knockout Model
- Mechanism of Cold Storage-Mediated Regulation of Heat Shock Proteins in Renal Grafts After Transplantation
Showing 5 of 11 shared publications
- Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function
- Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat
- Normal Proteasome Function Is Needed to Prevent Kidney Graft Injury during Cold Storage Followed by Transplantation
- Ischemia-Reperfusion-Mediated Kidney Injury Is Attenuated in a New Complement 5 Knockout Model
- Cold Storage-Mediated p38MAPK Activation: A Potential Contributor of Proteasome Dysfunction and Kidney Damage After Transplantation
Showing 5 of 8 shared publications
- Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat
- Ischemia-Reperfusion-Mediated Kidney Injury Is Attenuated in a New Complement 5 Knockout Model
- Ischemia and Reperfusion (IRI)-Induced Kidney Injury Is Attenuated by Complement 5 Gene Deletion (Abstract ID: 161749)
- Complement 5's Role in Mitochondria During Kidney Ischemia-Reperfusion Injury in Rats
- ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination
- Evolved histone tail regulates 53BP1 recruitment at damaged chromatin
- UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair
- Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function
- Mechanism of Impaired Protein Homeostasis in Kidney Grafts Following Cold Storage and Transplantation (Abstract ID: 162640)
- Heat shock protein 72 is a druggable target during cold storage to improve graft outcome after kidney transplantation
- Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat
- Mechanism of Impaired Protein Homeostasis in Kidney Grafts Following Cold Storage and Transplantation (Abstract ID: 162640)
- Heat shock protein 72 is a druggable target during cold storage to improve graft outcome after kidney transplantation
- Evolved histone tail regulates 53BP1 recruitment at damaged chromatin
- UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair
- Evolved histone tail regulates 53BP1 recruitment at damaged chromatin
- UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair
- Evolved histone tail regulates 53BP1 recruitment at damaged chromatin
- UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair
- Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function
- Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat
- Normal Proteasome Function Is Needed to Prevent Kidney Graft Injury during Cold Storage Followed by Transplantation
- Heat shock protein 72 is a druggable target during cold storage to improve graft outcome after kidney transplantation
- Mechanism of Impaired Protein Homeostasis in Kidney Grafts Following Cold Storage and Transplantation (Abstract ID: 162640)
- Heat shock protein 72 is a druggable target during cold storage to improve graft outcome after kidney transplantation
- Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat
- Complement 5's Role in Mitochondria During Kidney Ischemia-Reperfusion Injury in Rats
- Post‐ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat
- Complement 5's Role in Mitochondria During Kidney Ischemia-Reperfusion Injury in Rats
- ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination
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