Hong Wu

OverviewAI-generated summary

Hong Wu's research focuses on understanding and modulating the tumor microenvironment to improve cancer therapies. Wu has investigated the role of intratumoral microbiota in regulating responses to chemoimmunotherapy in esophageal squamous cell carcinoma and explored how hypoxia influences glioma tumor-associated macrophages to adopt a tumor-supportive phenotype. Further work has examined the mechanisms by which Tiam1 methylation promotes colon cancer metastasis and identified ITGA5 as a predictor of dual-drug resistance in glioma. Wu also has experience developing protocols for detecting macrophage-mediated cancer cell phagocytosis in vitro and in vivo.

Additional research interests include the development of pluripotent autologous tumor vaccines to enhance sequential immunotherapy for non-small cell lung cancer and the investigation of tumor necrosis factor inhibitors for recurrent spontaneous abortion. Wu has also contributed to materials science research, including the fabrication of 3D-printed composite scaffolds for Schwann cell growth.

With a career spanning 176 publications and 1448 citations, Wu holds an h-index of 21. Key collaborators include Luke Childress, Landon B. Gatrell, and Elisabeth Ferreira, all from the University of Arkansas for Medical Sciences.

Metrics

• h-index: 21
• Publications: 176
• Citations: 1,448