Hong Wu

OverviewAI-generated summary

Hong Wu's research program focuses on cancer biology, with a particular emphasis on understanding the tumor microenvironment and developing therapeutic strategies. Wu has investigated the role of microbiota in regulating chemoimmunotherapy response in esophageal squamous cell carcinoma and explored how mitophagy contributes to sorafenib resistance through hypoxia-inducible ATAD3A. Other work has examined the development of gene signatures for prognostic and predictive analyses in glioblastoma, and how SMYD3 controls epigenetic switches for cancer stem cell maintenance.

Further investigations by Wu include the mechanisms by which SIRPγ-expressing cancer stem-like cells promote immune escape in lung cancer via Hippo signaling. Additionally, research has explored the use of biocompatible probes for illuminating lung tumors based on viscosity confinement-mediated antiaggregation. Wu has also studied how hypoxia-induced polypoid giant cancer cells in glioma promote the transformation of tumor-associated macrophages to a tumor-supportive phenotype.

Wu's scholarship metrics include an h-index of 21, with a total of 176 publications and 1,448 citations. Wu has collaborated with Luke Childress, Landon B. Gatrell, and Elisabeth Ferreira, all at the University of Arkansas for Medical Sciences, with each collaboration resulting in one shared publication.

Metrics

• h-index: 21
• Publications: 176
• Citations: 1,448