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Biography and Research Information
OverviewAI-generated summary
Gang Li's research focuses on developing and applying advanced molecular and imaging techniques for disease diagnosis and therapy. His work has explored the engineering of biomotors for targeted nanodrug delivery and cell-based thrombolytic treatments. Li has also investigated plasmonic technologies for multi-scale biomedical imaging, contributing to improved visualization in medical contexts.
His recent publications highlight the design of activatable fluorescent probes for atherosclerosis imaging, utilizing molecular logic gates and responding to specific biological conditions like peroxynitrite and lipid droplet levels. Li's research also extends to therapeutic strategies for cardiovascular diseases, including diabetes-induced cardiomyopathy and pulmonary arterial hypertension, by targeting metabolic pathways and signaling cascades. He has also examined the role of lipid metabolism in hepatocellular carcinoma, investigating how targeting specific enzymes can sensitize cancer cells to chemotherapy. His work further includes the development of responsive gel systems and extracellular vesicles for promoting recovery after acute myocardial infarction.
Metrics
- h-index: 38
- Publications: 364
- Citations: 5,080
Selected Publications
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Resveratrol promotes diabetic wound healing by inhibiting ferroptosis in vascular endothelial cells (2024)
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Psilocybin for the treatment of Alzheimer’s disease (2024)
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The miR-182-5p/GPX4 Pathway Contributes to Sevoflurane-Induced Ototoxicity via Ferroptosis (2024)
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AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine (2024)
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Deletion of endothelial IGFBP5 protects against ischaemic hindlimb injury by promoting angiogenesis (2024)
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Melanin Nanoparticle-Modified Probiotics for Targeted Synergistic Therapy of Ulcerative Colitis (2024)
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Pyroptosis and mitochondrial function participated in miR-654-3p-protected against myocardial infarction (2024)
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NEDD4L is a promoter for angiogenesis and cell proliferation in human umbilical vein endothelial cells (2024)
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ARDS and aging: TYMS emerges as a promising biomarker and therapeutic target (2024)
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TRIM59 suppresses the brain ischaemia/reperfusion injury and pyroptosis of microglial through mediating the ubiquitination of NLRP3 (2024)
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NMDARs activation regulates endothelial ferroptosis via the PP2A-AMPK-HMGB1 axis (2024)
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Heterogeneous treatment effects of coronary artery bypass grafting in ischemic cardiomyopathy: A machine learning causal forest analysis (2023)
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The induction of ferroptosis by KLF11/NCOA4 axis: the inhibitory role in clear cell renal cell carcinoma (2023)
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Genetic Spectrum of Congenital Anomalies of the Kidney and Urinary Tract in Chinese Newborn Genome Project (2023)
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Bradykinin-pretreated Human cardiac-specific c-kit+ Cells Enhance Exosomal miR-3059-5p and Promote Angiogenesis Against Hindlimb Ischemia in mice (2023)
Collaboration Network
Top Collaborators
Wei‐Yin Wu
First Affiliated Hospital of Xiamen University (CN)
9 shared publications
- Acacetin attenuates diabetes-induced cardiomyopathy by inhibiting oxidative stress and energy metabolism via PPAR-α/AMPK pathway
- Acacetin alleviates myocardial ischaemia/reperfusion injury by inhibiting oxidative stress and apoptosis via the Nrf-2/HO-1 pathway
- Ubiquitinated ligation protein NEDD4L participates in MiR-30a-5p attenuated atherosclerosis by regulating macrophage polarization and lipid metabolism
- An overview of PAX1: Expression, function and regulation in development and diseases
- Concanavalin A promotes angiogenesis and proliferation in endothelial cells through the Akt/ERK/Cyclin D1 axis
Showing 5 of 9 shared publications
Fei Song
First Affiliated Hospital of Xiamen University (CN)
6 shared publications
- Heart-targeting exosomes from human cardiosphere-derived cells improve the therapeutic effect on cardiac hypertrophy
- Ubiquitinated ligation protein NEDD4L participates in MiR-30a-5p attenuated atherosclerosis by regulating macrophage polarization and lipid metabolism
- Long-Term Sleep Deprivation-Induced Myocardial Remodeling and Mitochondrial Dysfunction in Mice Were Attenuated by Lipoic Acid and N-Acetylcysteine
- NEDD4L is a promoter for angiogenesis and cell proliferation in human umbilical vein endothelial cells
- Bradykinin-pretreated Human cardiac-specific c-kit+ Cells Enhance Exosomal miR-3059-5p and Promote Angiogenesis Against Hindlimb Ischemia in mice
Showing 5 of 6 shared publications
Yan Wang
Xiamen University (CN)
5 shared publications
- Advanced plasmonic technologies for multi-scale biomedical imaging
- An “AND” Molecular Logic Gate as a Super‐Enhancers for De Novo Designing Activatable Probe and Its Application in Atherosclerosis Imaging
- Heart-targeting exosomes from human cardiosphere-derived cells improve the therapeutic effect on cardiac hypertrophy
- NMDARs antagonist MK801 suppresses LPS-induced apoptosis and mitochondrial dysfunction by regulating subunits of NMDARs via the CaM/CaMKII/ERK pathway
- Pyroptosis and mitochondrial function participated in miR-654-3p-protected against myocardial infarction
Chan Wu
Zhongshan Hospital of Xiamen University (CN)
4 shared publications
- Heart-targeting exosomes from human cardiosphere-derived cells improve the therapeutic effect on cardiac hypertrophy
- Pretreatment of cardiac progenitor cells with bradykinin attenuates H2O2-induced cell apoptosis and improves cardiac function in rats by regulating autophagy
- NEDD4L is a promoter for angiogenesis and cell proliferation in human umbilical vein endothelial cells
- Bradykinin-pretreated Human cardiac-specific c-kit+ Cells Enhance Exosomal miR-3059-5p and Promote Angiogenesis Against Hindlimb Ischemia in mice
Xiaoxia Zhou
Xiamen University (CN)
4 shared publications
- Concanavalin A promotes angiogenesis and proliferation in endothelial cells through the Akt/ERK/Cyclin D1 axis
- Pretreatment of cardiac progenitor cells with bradykinin attenuates H2O2-induced cell apoptosis and improves cardiac function in rats by regulating autophagy
- NEDD4L is a promoter for angiogenesis and cell proliferation in human umbilical vein endothelial cells
- Bradykinin-pretreated Human cardiac-specific c-kit+ Cells Enhance Exosomal miR-3059-5p and Promote Angiogenesis Against Hindlimb Ischemia in mice
Jinrong Zheng
Zhongshan Hospital of Xiamen University (CN)
4 shared publications
- Enzyme Catalysis Biomotor Engineering of Neutrophils for Nanodrug Delivery and Cell-Based Thrombolytic Therapy
- An “AND” Molecular Logic Gate as a Super‐Enhancers for De Novo Designing Activatable Probe and Its Application in Atherosclerosis Imaging
- Peroxynitrite/Lipid Droplet Sequence-Activated Dual-Lock Fluorescent Probes Enable Precise Intraoperative Imaging of Atherosclerotic Plaques
- Lipid‐Activatable Fluorescent Probe for Intraoperative Imaging of Atherosclerotic Plaque Using In Situ Patch
Mangmang Sang
Zhongshan Hospital of Xiamen University (CN)
4 shared publications
- Enzyme Catalysis Biomotor Engineering of Neutrophils for Nanodrug Delivery and Cell-Based Thrombolytic Therapy
- An “AND” Molecular Logic Gate as a Super‐Enhancers for De Novo Designing Activatable Probe and Its Application in Atherosclerosis Imaging
- Peroxynitrite/Lipid Droplet Sequence-Activated Dual-Lock Fluorescent Probes Enable Precise Intraoperative Imaging of Atherosclerotic Plaques
- Lipid‐Activatable Fluorescent Probe for Intraoperative Imaging of Atherosclerotic Plaque Using In Situ Patch
Cuilian Dai
Xiamen University (CN)
4 shared publications
- Enzyme Catalysis Biomotor Engineering of Neutrophils for Nanodrug Delivery and Cell-Based Thrombolytic Therapy
- An “AND” Molecular Logic Gate as a Super‐Enhancers for De Novo Designing Activatable Probe and Its Application in Atherosclerosis Imaging
- Peroxynitrite/Lipid Droplet Sequence-Activated Dual-Lock Fluorescent Probes Enable Precise Intraoperative Imaging of Atherosclerotic Plaques
- An overview of PAX1: Expression, function and regulation in development and diseases
Yi‐Xiang Hong
First Affiliated Hospital of Xiamen University (CN)
4 shared publications
- Heart-targeting exosomes from human cardiosphere-derived cells improve the therapeutic effect on cardiac hypertrophy
- NMDARs antagonist MK801 suppresses LPS-induced apoptosis and mitochondrial dysfunction by regulating subunits of NMDARs via the CaM/CaMKII/ERK pathway
- NMDARs activation regulates endothelial ferroptosis via the PP2A-AMPK-HMGB1 axis
- Deletion of endothelial IGFBP5 protects against ischaemic hindlimb injury by promoting angiogenesis
Hukui Han
University of Electronic Science and Technology of China (CN)
3 shared publications
- A pH/H<sub>2</sub>O<sub>2</sub>/MMP9 Time‐Response Gel System with Sparc<sup>high</sup> Tregs Derived Extracellular Vesicles Promote Recovery After Acute Myocardial Infarction
- Low- or high-dose preventive aspirin use and risk of death from all-cause, cardiovascular disease, and cancer: A nationally representative cohort study
- Comprehensive Analysis of the Immune Infiltrates and Aberrant Pathways Activation in Atherosclerotic Plaque
Jing-Zhou Li
Xiamen University (CN)
3 shared publications
- Ubiquitinated ligation protein NEDD4L participates in MiR-30a-5p attenuated atherosclerosis by regulating macrophage polarization and lipid metabolism
- Concanavalin A promotes angiogenesis and proliferation in endothelial cells through the Akt/ERK/Cyclin D1 axis
- Pretreatment of cardiac progenitor cells with bradykinin attenuates H2O2-induced cell apoptosis and improves cardiac function in rats by regulating autophagy
Weimin Han
Xiamen University (CN)
3 shared publications
- NMDARs antagonist MK801 suppresses LPS-induced apoptosis and mitochondrial dysfunction by regulating subunits of NMDARs via the CaM/CaMKII/ERK pathway
- NMDARs activation regulates endothelial ferroptosis via the PP2A-AMPK-HMGB1 axis
- Bradykinin-pretreated Human cardiac-specific c-kit+ Cells Enhance Exosomal miR-3059-5p and Promote Angiogenesis Against Hindlimb Ischemia in mice
Panke Cheng
University of Electronic Science and Technology of China (CN)
2 shared publications
- A pH/H<sub>2</sub>O<sub>2</sub>/MMP9 Time‐Response Gel System with Sparc<sup>high</sup> Tregs Derived Extracellular Vesicles Promote Recovery After Acute Myocardial Infarction
- Comprehensive Analysis of the Immune Infiltrates and Aberrant Pathways Activation in Atherosclerotic Plaque
Chen Yang
University of Electronic Science and Technology of China (CN)
2 shared publications
- A pH/H<sub>2</sub>O<sub>2</sub>/MMP9 Time‐Response Gel System with Sparc<sup>high</sup> Tregs Derived Extracellular Vesicles Promote Recovery After Acute Myocardial Infarction
- Comprehensive Analysis of the Immune Infiltrates and Aberrant Pathways Activation in Atherosclerotic Plaque
Haifeng Qiang
Xiamen University (CN)
2 shared publications
- Concanavalin A promotes angiogenesis and proliferation in endothelial cells through the Akt/ERK/Cyclin D1 axis
- Pretreatment of cardiac progenitor cells with bradykinin attenuates H2O2-induced cell apoptosis and improves cardiac function in rats by regulating autophagy
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