Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-20
J
J. Craig Forrest
Federal Grant PI
High Impact
Professor
Also affiliated: Harvard University (2003); Emory University (2007–2010); Emory and Henry College (2010); Vanderbilt University (2001–2006); Massachusetts General Hospital (2003); Bipar (2006); Tennessee Department of Health (2001); Winthrop Rockefeller Foundation (2019–2026); Atlanta VA Medical Center (2007–2008)
Faculty Researcher
27 h-index
68 pubs
2,962 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
J. Craig Forrest's research focuses on gammaherpesvirus pathogenesis, viral latency, and host-pathogen interactions, with a particular emphasis on B-lymphocytes and signal transduction pathways. His work has been supported by multiple NIH grants totaling over $2 million, including funding to define mechanisms of gammaherpesvirus-driven genomic instability in B cells, KSHV LANA functions in viral pathogenesis, and the role of lytic viral genes in oncogenic gammaherpesviruses. He also investigates the pathogenesis of gammaherpesvirus and Plasmodium coinfections and the role of periodontal bacteria in oral KSHV pathogenesis.
Forrest has published 67 papers, accumulating over 2,900 citations and an h-index of 27. His recent publications include studies on the establishment and maintenance of gammaherpesvirus latency in B cells, the protective effects of a replication-deficient gammaherpesvirus vaccine in mice, and the role of STAT3 in viral latency and interferon suppression. He has also contributed to research on SARS-CoV-2, including studies on ACE2 autoantibodies and pediatric seroprevalence in Arkansas.
His collaborations within the University of Arkansas for Medical Sciences include 17 shared publications with Shana M. Owens, 13 with Joshua L. Kennedy, and 6 with Catherine Kirkpatrick. Forrest is designated as a high-impact researcher and a federal grant principal investigator.
Metrics
- h-index: 27
- Publications: 68
- Citations: 2,962
Selected Publications
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Repression of productive viral replication by KSHV LANA correlates with reduced adaptive immune activation: potential implications for KSHV immune evasion (2026)
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Single cell in vivo analysis of type I IFN and NK cell-mediated control of B cell infection densities during acute gammaherpesvirus infection (2026)
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The amplitude of gammaherpesvirus lytic replication dictates adaptive immune activation: Potential implications for KSHV LANA in immune evasion (2026)
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Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment (2025)
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Vaccination with a Replication-Dead Murine Gammaherpesvirus Lacking Viral Pathogenesis Genes Inhibits WT Virus Infection (2024)
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Vaccination with a Replication-Dead Murine Gammaherpesvirus Lacking Viral Pathogenesis Genes Inhibits WT Virus Infection (2024)
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Molecular Mechanisms of KSHV Latency Establishment and Maintenance (2024)
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A replication-deficient gammaherpesvirus vaccine protects mice from lytic disease and reduces latency establishment (2024)
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Multifaceted roles for STAT3 in gammaherpesvirus latency revealed through <i>in vivo</i> B cell knockout models (2024)
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Intrinsic p53 Activation Restricts Gammaherpesvirus-Driven Germinal Center B Cell Expansion during Latency Establishment (2023)
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Replication-dead gammaherpesvirus vaccine protects against acute replication, reactivation from latency, and lethal challenge in mice (2023)
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Uracil-DNA glycosylase of murine gammaherpesvirus 68 binds cognate viral replication factors independently of its catalytic residues (2023)
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A longitudinal study of SARS-CoV-2 antibody seroprevalence and mitigation behaviors among college students at an Arkansas University (2023)
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Uracil-DNA Glycosylase of Murine Gammaherpesvirus 68 Binds Cognate Viral Replication Factors Independently of its Catalytic Residues (2023)
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B cell-intrinsic STAT3-mediated support of latency and interferon suppression during murine gammaherpesvirus 68 infection revealed through an <i>in vivo</i> competition model (2023)
Federal Grants 5 $2,050,700 total
NIH
Contact PI
Apr 2026 - Mar 2031
Defining the pathogenesis of gammaherpesvirus and Plasmodium coinfections
NIH
Contact PI
Jun 2025 - May 2027
Lytic viral genes in the pathogenesis of oncogenic gammaherpesviruses
NIH
Contact PI
Jul 2024 - May 2029
Defining KSHV LANA functions in viral pathogenesis and immune evasion
NIH
Co-PI
Mar 2019 - Apr 2025
NIH
Contact PI
Apr 2014 - Feb 2027
Defining mechanisms of gammaherpesvirus-driven genomic instability in B cells
Collaboration Network
Top Collaborators
Shana M. Owens
University of Arkansas for Medical Sciences
14 shared publications
In database
- Development of ACE2 autoantibodies after SARS-CoV-2 infection
- Pediatric SARS-CoV-2 Seroprevalence in Arkansas Over the First Year of the COVID-19 Pandemic
- Temporal Variations in Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infections by Race and Ethnicity in Arkansas
- A replication-deficient gammaherpesvirus vaccine protects mice from lytic disease and reduces latency establishment
- Lytic Replication and Reactivation from B Cells Is Not Required for Establishing or Maintaining Gammaherpesvirus Latency <i>In Vivo</i>
Showing 5 of 14 shared publications
Karl W. Boehme
Inflammatory Response Research (United States)
9 shared publications
In database
- Development of ACE2 autoantibodies after SARS-CoV-2 infection
- The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization
- Pediatric SARS-CoV-2 Seroprevalence in Arkansas Over the First Year of the COVID-19 Pandemic
- State-wide random seroprevalence survey of SARS-CoV-2 past infection in a southern US State, 2020
- Modifying laboratory testing via home brew during the COVID-19 pandemic
Showing 5 of 9 shared publications
Joshua L. Kennedy
Arkansas Children's Hospital
8 shared publications
In database
- Development of ACE2 autoantibodies after SARS-CoV-2 infection
- Pediatric SARS-CoV-2 Seroprevalence in Arkansas Over the First Year of the COVID-19 Pandemic
- Temporal Variations in Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infections by Race and Ethnicity in Arkansas
- State-wide random seroprevalence survey of SARS-CoV-2 past infection in a southern US State, 2020
- Temporal Variations in Seroprevalence of SARS-CoV-2 Infections by Race and Ethnicity in Arkansas
Showing 5 of 8 shared publications
Darby G. Oldenburg
8 shared publications
- Lytic Replication and Reactivation from B Cells Is Not Required for Establishing or Maintaining Gammaherpesvirus Latency <i>In Vivo</i>
- Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment
- Uracil-DNA glycosylase of murine gammaherpesvirus 68 binds cognate viral replication factors independently of its catalytic residues
- Lytic Replication and Reactivation from B Cells Is Not Required for Maintaining Gammaherpesvirus Latency <i>in vivo</i>
- Uracil-DNA Glycosylase of Murine Gammaherpesvirus 68 Binds Cognate Viral Replication Factors Independently of its Catalytic Residues
Showing 5 of 8 shared publications
Laurie T. Krug
National Cancer Institute (US)
8 shared publications
- A replication-deficient gammaherpesvirus vaccine protects mice from lytic disease and reduces latency establishment
- B cell-intrinsic STAT3-mediated support of latency and interferon suppression during murine gammaherpesvirus 68 infection revealed through an <i>in vivo</i> competition model
- Multifaceted roles for STAT3 in gammaherpesvirus latency revealed through <i>in vivo</i> B cell knockout models
- Uracil-DNA glycosylase of murine gammaherpesvirus 68 binds cognate viral replication factors independently of its catalytic residues
- Uracil-DNA Glycosylase of Murine Gammaherpesvirus 68 Binds Cognate Viral Replication Factors Independently of its Catalytic Residues
Showing 5 of 8 shared publications
Laura P. James
University of Arkansas for Medical Sciences
7 shared publications
In database
- Pediatric SARS-CoV-2 Seroprevalence in Arkansas Over the First Year of the COVID-19 Pandemic
- Temporal Variations in Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infections by Race and Ethnicity in Arkansas
- State-wide random seroprevalence survey of SARS-CoV-2 past infection in a southern US State, 2020
- Modifying laboratory testing via home brew during the COVID-19 pandemic
- Temporal Variations in Seroprevalence of SARS-CoV-2 Infections by Race and Ethnicity in Arkansas
Showing 5 of 7 shared publications
Catherine Kirkpatrick
Arkansas Children's Hospital
6 shared publications
In database
- Pediatric SARS-CoV-2 Seroprevalence in Arkansas Over the First Year of the COVID-19 Pandemic
- Temporal Variations in Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infections by Race and Ethnicity in Arkansas
- State-wide random seroprevalence survey of SARS-CoV-2 past infection in a southern US State, 2020
- Temporal Variations in Seroprevalence of SARS-CoV-2 Infections by Race and Ethnicity in Arkansas
- Pediatric SARS-CoV-2 seroprevalence in Arkansas over the first year of the COVID-19 pandemic
Showing 5 of 6 shared publications
Namvar Zohoori
Arkansas Department of Health (US)
6 shared publications
- Pediatric SARS-CoV-2 Seroprevalence in Arkansas Over the First Year of the COVID-19 Pandemic
- Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies
- Temporal Variations in Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infections by Race and Ethnicity in Arkansas
- State-wide random seroprevalence survey of SARS-CoV-2 past infection in a southern US State, 2020
- Temporal Variations in Seroprevalence of SARS-CoV-2 Infections by Race and Ethnicity in Arkansas
Showing 5 of 6 shared publications
Benjamin C. Amick
Winthrop Rockefeller Foundation
5 shared publications
In database
- Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies
- Temporal Variations in Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infections by Race and Ethnicity in Arkansas
- State-wide random seroprevalence survey of SARS-CoV-2 past infection in a southern US State, 2020
- Temporal Variations in Seroprevalence of SARS-CoV-2 Infections by Race and Ethnicity in Arkansas
- A longitudinal study of SARS-CoV-2 antibody seroprevalence and mitigation behaviors among college students at an Arkansas University
Jessica Snowden
Arkansas Children's Hospital
5 shared publications
In database
- Pediatric SARS-CoV-2 Seroprevalence in Arkansas Over the First Year of the COVID-19 Pandemic
- Temporal Variations in Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infections by Race and Ethnicity in Arkansas
- Temporal Variations in Seroprevalence of SARS-CoV-2 Infections by Race and Ethnicity in Arkansas
- Pediatric SARS-CoV-2 seroprevalence in Arkansas over the first year of the COVID-19 pandemic
- A longitudinal study of SARS-CoV-2 antibody seroprevalence and mitigation behaviors among college students at an Arkansas University
Zeel Modi
Arkansas Children's Hospital (US)
5 shared publications
- Pediatric SARS-CoV-2 Seroprevalence in Arkansas Over the First Year of the COVID-19 Pandemic
- Temporal Variations in Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infections by Race and Ethnicity in Arkansas
- State-wide random seroprevalence survey of SARS-CoV-2 past infection in a southern US State, 2020
- Temporal Variations in Seroprevalence of SARS-CoV-2 Infections by Race and Ethnicity in Arkansas
- Pediatric SARS-CoV-2 seroprevalence in Arkansas over the first year of the COVID-19 pandemic
Katherine Caid
Arkansas Children's Hospital (US)
5 shared publications
- Pediatric SARS-CoV-2 Seroprevalence in Arkansas Over the First Year of the COVID-19 Pandemic
- Temporal Variations in Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infections by Race and Ethnicity in Arkansas
- State-wide random seroprevalence survey of SARS-CoV-2 past infection in a southern US State, 2020
- Temporal Variations in Seroprevalence of SARS-CoV-2 Infections by Race and Ethnicity in Arkansas
- Pediatric SARS-CoV-2 seroprevalence in Arkansas over the first year of the COVID-19 pandemic
Wendy N. Nembhard
University of Arkansas for Medical Sciences
5 shared publications
In database
- Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies
- Temporal Variations in Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infections by Race and Ethnicity in Arkansas
- State-wide random seroprevalence survey of SARS-CoV-2 past infection in a southern US State, 2020
- Temporal Variations in Seroprevalence of SARS-CoV-2 Infections by Race and Ethnicity in Arkansas
- A longitudinal study of SARS-CoV-2 antibody seroprevalence and mitigation behaviors among college students at an Arkansas University
Ericka Olgaard
University of Arkansas for Medical Sciences
4 shared publications
In database
- State-wide random seroprevalence survey of SARS-CoV-2 past infection in a southern US State, 2020
- Modifying laboratory testing via home brew during the COVID-19 pandemic
- Temporal Variations in Seroprevalence of SARS-CoV-2 Infections by Race and Ethnicity in Arkansas
- A longitudinal study of SARS-CoV-2 antibody seroprevalence and mitigation behaviors among college students at an Arkansas University
Mark L. Williams
University of Arkansas for Medical Sciences
4 shared publications
In database
- Temporal Variations in Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infections by Race and Ethnicity in Arkansas
- State-wide random seroprevalence survey of SARS-CoV-2 past infection in a southern US State, 2020
- Temporal Variations in Seroprevalence of SARS-CoV-2 Infections by Race and Ethnicity in Arkansas
- A longitudinal study of SARS-CoV-2 antibody seroprevalence and mitigation behaviors among college students at an Arkansas University
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