Graham M. Strub
Associate Professor
faculty
Otolaryngology, College of Medicine
Research Areas
Biography and Research Information
OverviewAI-generated summary
Graham M. Strub's research focuses on vascular anomalies, particularly in children. His work investigates the molecular mechanisms driving the proliferation of endothelial cells in conditions like arteriovenous malformations and lymphatic malformations. Recent publications explore the dysregulation of signaling pathways such as TGF-β/BMP, the role of microRNAs like miR-21 in cell proliferation by targeting specific genes, and the process of endothelial-to-mesenchymal transition in these anomalies. Strub also contributes to practice patterns and genetic testing recommendations for vascular anomalies within pediatric otolaryngology. His research extends to quantitative proteomic analysis in children undergoing surgical procedures related to pulmonary arteriovenous malformations. Additionally, Strub has published on topics including subcutaneous emphysema following facial injury and the differential diagnosis of neck masses, as well as algorithms for improving diversity in residency interviews.
Metrics
- h-index: 10
- Publications: 41
- Citations: 3,252
Selected Publications
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Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells (2025)
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Toward an Unbiased Deep Learning Classifier of Pediatric Middle Ear Disease (2025)
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Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs (2024)
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Advanced laryngeal squamous cell carcinoma in an adolescent: A case and treatment considerations (2024)
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Quantitative plasma proteomic analysis in children after superior cavopulmonary anastomosis with pulmonary arteriovenous malformations (2024)
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Massive Subcutaneous Emphysema after Hydrogen Peroxide Irrigation of a Penetrating Facial Injury (2023)
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Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4 (2023)
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Genetic testing for vascular anomalies – American society of pediatric otolaryngology vascular anomalies task force practice patterns (2022)
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Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1 (2022)
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A novel algorithm to reduce bias and improve the quality and diversity of residency interviewees (2022)
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Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1 (2022)
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Bronchogenic cyst of the posterior neck mimicking lymphatic malformation (2022)
Grants & Funding
- Next Generation Treatments for Lymphatic Malformations NIH Principal Investigator
- No FP attached UAMS ACHRI Flow Through Principal Investigator
- No FP attached UAMS ACHRI Flow Through Principal Investigator
- No FP attached UAMS ACHRI Flow Through Principal Investigator
- AWD-034171: 4517 - CTPR Phase II - Admin Core 07/01/2022 (version 0) Grant: GR034175 4687 Tackett COBRE CTPR Phase II - Project 5 Strub UAMS ACHRI Flow Through Principal Investigator
- Intracellular Target of Sphingosine-1-Phosphate NIH Principal Investigator
- No FP attached UAMS ACHRI Flow Through Principal Investigator
Collaboration Network
Top Collaborators
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Quantitative plasma proteomic analysis in children after superior cavopulmonary anastomosis with pulmonary arteriovenous malformations
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
Showing 5 of 8 shared publications
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
Showing 5 of 6 shared publications
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Quantitative plasma proteomic analysis in children after superior cavopulmonary anastomosis with pulmonary arteriovenous malformations
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
Showing 5 of 6 shared publications
- A novel algorithm to reduce bias and improve the quality and diversity of residency interviewees
- Toward an Unbiased Deep Learning Classifier of Pediatric Middle Ear Disease
- Artificial intelligence classification of pediatric middle ear effusion using consumer-grade otoscopes
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Quantitative plasma proteomic analysis in children after superior cavopulmonary anastomosis with pulmonary arteriovenous malformations
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Bronchogenic cyst of the posterior neck mimicking lymphatic malformation
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
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