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Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-09
Jason E. Farrar
High Impact
Professor
Also affiliated: University of Southern California (2023); Cincinnati Children's Hospital Medical Center (2025); Arkansas Children's Hospital (2014–2026); St. Jude Children's Research Hospital (1996); Johns Hopkins University (2005–2012); Chiba University (2008); University of Tennessee Health Science Center (1996); University of Arkansas Medical Center (2018–2024); Johns Hopkins Medicine (2005–2012); Fred Hutch Cancer Center (2023); National Human Genome Research Institute (2015); Sidney Kimmel Cancer Center (2008); Children's Oncology Group (2016–2023); Johns Hopkins Hospital (2009–2010); Sidney Kimmel Comprehensive Cancer Center (2007–2012); Arkansas Children's Research Institute (2016–2026)
Peds Pediatrics, College of Medicine
25 h-index
149 pubs
3,223 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Jason E. Farrar studies pediatric acute myeloid leukemia (AML) and Diamond-Blackfan anemia. His research investigates the molecular and clinical characteristics of these conditions, including specific gene fusions like NUP98 and the role of long noncoding RNAs in predicting outcomes for pediatric AML. Farrar has also examined the mechanisms by which certain genetic alterations, such as ZMYND11-MBTD1, contribute to leukemogenesis through interactions with chromatin remodeling complexes.
His work includes contributions to international consensus statements on the diagnosis, treatment, and surveillance of Diamond-Blackfan anemia. Farrar is also involved in research on implementing pharmacogenomics testing in pediatric settings, as demonstrated by his experience at Arkansas Children’s Hospital. He has received funding from the NIH/National Center for Advancing Translational Sciences as a Co-PI for the CTSA K12 Program at the University of Arkansas for Medical Sciences, totaling $756,000.
Farrar holds the designation of a high-impact researcher, evidenced by his h-index of 25 and over 3,000 citations across 149 publications. His key collaborators include Samrat Roy Choudhury, Lauren Appell, Stephanie D. Byrum, and LE Appell, all from the University of Arkansas for Medical Sciences, with whom he has co-authored multiple publications.
Metrics
- h-index: 25
- Publications: 149
- Citations: 3,223
Positions
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Professor 2012–presentUniversity of Arkansas for Medical Sciences Peds Pediatrics, College of Medicine Institutional directory
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Arkansas Childrens Hospital 2012–presentORCID
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Instructor 2007–2012Johns Hopkins Medicine Oncology/Pediatric Oncology ORCID
Selected Publications
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Feasibility of Non-Sedated Multispectral Neuroimaging in Newly Diagnosed Children with Leukemia (2026)
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Abstract 3496: Epigenetic repurposing by CBFA2T3-GLIS2 reveals a druggable DNA methylation axis in high-risk pediatric AML vulnerability in pediatric AML (2026)
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Central nervous system-symptomatic hyperammonemia following recombinant crisantaspase Pseudomonas fluorescens (2026)
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A supervised STreNgth & Outpatient Exercise Regimen in pediatric patients with Acute Lymphoblastic Leukemia (STRONGER ALL) (2026)
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Abstract PR006: CBFA2T3–GLIS2 fusion reprograms enhancer-linked DNA methylation to enforce apoptotic resistance and defines an epigenetic vulnerability in pediatric AML (2026)
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Transcriptional rewiring by enhancer methylation in CBFA2T3-GLIS2–driven pediatric acute megakaryoblastic leukemia (2025)
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Germline Variant Burden Warrants Universal Genetic Testing in Pediatric Myeloid Leukemia (2025)
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Eltrombopag in combination with immunosuppressive therapy in pediatric severe aplastic anemia: phase 2 ESCALATE trial (2025)
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130 A supervised strength and outpatient exercise regimen in pediatric patients with acute lymphoblastic leukemia (STRONGER ALL) (2025)
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Lymphoid malignancies in patients with Shwachman-Diamond syndrome (2025)
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Lymphoid Malignancies in Shwachman-Diamond Syndrome (2024)
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Evaluation of recurrent and recalcitrant warts in a deaf adolescent male reveals GATA2 deficiency (2024)
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Diagnosis, treatment, and surveillance of Diamond-Blackfan anaemia syndrome: international consensus statement (2024)
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Abstract P16: CBFA2T3-GLIS2 fusion leads to a distinct DNA methylation enhancer landscape in pediatric acute myeloid leukemia (2024)
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Enhancer‐activated <scp>RET</scp> confers protection against oxidative stress to <scp>KMT2A</scp>‐rearranged acute myeloid leukemia (2024)
Federal Grants 1 $756,000 total
NIH
Co-PI
Jul 2024 - Jun 2029
CTSA K12 Program at the University of Arkansas for Medical Sciences
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- GR034151 Farrar ACHRI Mechanisms of Erythroid Remission in Diamond Blackfan Anemia (DBA) UAMS ACHRI Flow Through Principal Investigator
- Integrative Genomics in Pediatric AML Arkansas Children's Research Institute Principal Investigator
- Role of HELB in the Replication Stress Response Dr. Tacketts COBRA through ACRI NIH/Nat. Inst. of General Medical Sciences via Arkansas Children's Research Institute Principal Investigator
- St. Baldrick's Subaward St. Baldrick's Foundation via Fred Hutchinson Cancer Research Center Principal Investigator
- GR039178-Farrar-ACRI Proteogenomics Core UAMS ACHRI Flow Through Principal Investigator
- Tackett COBRE-SUBAward J Farrar Project 1 - Continuation - Continuation NIH/Nat. Inst. of General Medical Sciences via Arkansas Children's Hospital Principal Investigator
- Epigenomic Characterization of Pediatric AML UAMS ACHRI Flow Through Principal Investigator
- Mechanisms of Erythroid Remission in Diamond Blackfan Anemia (DBA) NIH Principal Investigator
- Control of pituitary cell plasticity through regulated mRNA translation NIH Co-Investigator
- Functional Analysis of RPL35A Alterations in Diamond Blackfan Anemia NIH Principal Investigator
- Tropic Roles for Leptin in the Maturation of Somatotropes NIH Co-Investigator
Collaboration Network
Top Collaborators
Soheil Meshinchi
Fred Hutch Cancer Center (US)
35 shared publications
- CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML
- Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia
- A multicenter, randomized study of decitabine as epigenetic priming with induction chemotherapy in children with AML
- Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia
- Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative
Showing 5 of 35 shared publications
Rhonda E. Ries
Fred Hutch Cancer Center (US)
33 shared publications
- The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
- CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML
- Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia
- Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia
- Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative
Showing 5 of 33 shared publications
Alan S. Gamis
Children's Mercy Hospital (US)
24 shared publications
- The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
- CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML
- Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia
- Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia
- Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative
Showing 5 of 24 shared publications
Todd A. Alonzo
University of Southern California (US)
24 shared publications
- The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
- CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML
- Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia
- Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia
- Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative
Showing 5 of 24 shared publications
E. Anders Kolb
DuPont (United States) (US)
21 shared publications
- The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
- CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML
- Molecular and phenotypic diversity of <I>CBL</I>-mutated juvenile myelomonocytic leukemia
- Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia
- Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia
Showing 5 of 21 shared publications
Tanja M. Davidsen
National Cancer Institute (US)
16 shared publications
- The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
- CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML
- Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative
- Publisher Correction: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
- Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution From Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – an NCI/COG Target AML Study
Showing 5 of 16 shared publications
Daniela S. Gerhard
National Cancer Institute (US)
16 shared publications
- CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML
- Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative
- Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution From Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – an NCI/COG Target AML Study
- Discovery and Validation of Cell-Surface Protein Mesothelin (MSLN) As a Novel Therapeutic Target in AML: Results from the COG/NCI Target AML Initiative
- The Role of FAS Receptor Methylation in Osteosarcoma Metastasis
Showing 5 of 16 shared publications
Adrianna Vlachos
Feinstein Institute for Medical Research (US)
16 shared publications
- Exploiting pre‐rRNA processing in <scp>D</scp>iamond <scp>B</scp>lackfan anemia gene discovery and diagnosis
- Diagnosis, treatment, and surveillance of Diamond-Blackfan anaemia syndrome: international consensus statement
- Increased Prevalence of Congenital Heart Disease in Children With Diamond Blackfan Anemia Suggests Unrecognized Diamond Blackfan Anemia as a Cause of Congenital Heart Disease in the General Population
- Molecular convergence in ex vivo models of Diamond-Blackfan anemia
- L‐leucine improves anemia and growth in patients with transfusion‐dependent Diamond‐Blackfan anemia: Results from a multicenter pilot phase I/II study from the Diamond‐Blackfan Anemia Registry
Showing 5 of 16 shared publications
Timothy J. Triche
University of Southern California (US)
16 shared publications
- A multicenter, randomized study of decitabine as epigenetic priming with induction chemotherapy in children with AML
- Publisher Correction: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
- Structural Variants Involving MLLT10/AF10 Are Associated with Adverse Outcome in AML Regardless of the Partner Gene - a COG/Tpaml Study
- CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes
- Integrated Stem Cell Signature and Cytomolecular Risk Determination in Pediatric Acute Myeloid Leukemia
Showing 5 of 16 shared publications
Malcolm A. Smith
National Cancer Institute (US)
15 shared publications
- CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML
- Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative
- Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution From Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – an NCI/COG Target AML Study
- Discovery and Validation of Cell-Surface Protein Mesothelin (MSLN) As a Novel Therapeutic Target in AML: Results from the COG/NCI Target AML Initiative
- Genome Wide Promoter Methylation Patterns Predict AML Subtype Outcomes and Identify Novel Pathways Characterizing Diagnostic and Relapsed Disease in Children
Showing 5 of 15 shared publications
Patee Gesuwan
National Cancer Institute (US)
14 shared publications
- The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
- CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML
- Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative
- Publisher Correction: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
- Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution From Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – an NCI/COG Target AML Study
Showing 5 of 14 shared publications
Marco A. Marra
Canada's Michael Smith Genome Sciences Centre (CA)
13 shared publications
- The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
- CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML
- Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative
- Publisher Correction: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
- Discovery and Validation of Cell-Surface Protein Mesothelin (MSLN) As a Novel Therapeutic Target in AML: Results from the COG/NCI Target AML Initiative
Showing 5 of 13 shared publications
Jenny L. Smith
Fred Hutch Cancer Center (US)
13 shared publications
- Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia
- Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia
- A B-cell developmental gene regulatory network is activated in infant AML
- Structural Variants Involving MLLT10/AF10 Are Associated with Adverse Outcome in AML Regardless of the Partner Gene - a COG/Tpaml Study
- CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes
Showing 5 of 13 shared publications
R.J. Arceci
University of Louisville (US)
12 shared publications
- Exploiting pre‐rRNA processing in <scp>D</scp>iamond <scp>B</scp>lackfan anemia gene discovery and diagnosis
- A multicenter, randomized study of decitabine as epigenetic priming with induction chemotherapy in children with AML
- Diminutive somatic deletions in the 5q region lead to a phenotype atypical of classical 5q− syndrome
- Outlier Analysis and Top Scoring Pair for Integrated Data Analysis and Biomarker Discovery
- Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution From Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – an NCI/COG Target AML Study
Showing 5 of 12 shared publications
Robert B. Gerbing
Children's Oncology Group (US)
12 shared publications
- CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML
- Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia
- Structural Variants Involving MLLT10/AF10 Are Associated with Adverse Outcome in AML Regardless of the Partner Gene - a COG/Tpaml Study
- CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes
- Discovery and Validation of Cell-Surface Protein Mesothelin (MSLN) As a Novel Therapeutic Target in AML: Results from the COG/NCI Target AML Initiative
Showing 5 of 12 shared publications
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