Match tier
Likely match
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-16
K
Karthikeyan Mythreye
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
Associate Professor
Faculty Researcher
29 h-index
223 pubs
3,043 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Karthikeyan Mythreye investigates the molecular mechanisms underlying cancer progression, with a particular focus on ovarian cancer. His research explores the roles of signal transduction pathways, such as transforming growth factor beta (TGFβ) signaling, and specific molecules like SOX2, SMAD1, and SMAD3 in promoting cancer cell resistance to anoikis and facilitating metastasis. Mythreye's work also examines the influence of the tumor microenvironment, including the ascites environment in ovarian cancer, on cellular metabolism and growth factor relationships. He has published research on the stress-responsive lncRNA PVT1 and its role in driving ovarian cancer metastasis and chemoresistance, as well as the impact of hypoxia-induced inhibin on tumor growth and vascular permeability.
His scholarship extends to bioinformatic analyses, identifying prognostic markers like the inhibin-betaglycan-endoglin/CD105 network in various solid tumors. Mythreye also studies cellular adaptations to anchorage independence, such as HuR-dependent SOD2 protein synthesis. His research network includes collaborators like Nadine Hempel and Analiz Rodriguez. Mythreye's work contributes to understanding disease mechanisms and identifying potential therapeutic targets in cancer.
Metrics
- h-index: 29
- Publications: 223
- Citations: 3,043
Selected Publications
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Abstract 2264 Role of atypical Mitogen-Activated Protein Kinase 15 (MAPK15) in ovarian cancer cell survival and metastasis (2025)
Collaboration Network
Top Collaborators
Nam Y. Lee
University of Arizona (US)
28 shared publications
- TGFβ signaling networks in ovarian cancer progression and plasticity
- Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer
- A bioinformatic analysis of the inhibin-betaglycan-endoglin/CD105 network reveals prognostic value in multiple solid tumors
- Hypoxia-induced inhibin promotes tumor growth and vascular permeability in ovarian cancers
- βIV-spectrin as a stalk cell-intrinsic regulator of VEGF signaling
Showing 5 of 28 shared publications
Nadine Hempel
University of Pittsburgh
28 shared publications
In database
- Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer
- Emerging perspectives on growth factor metabolic relationships in the ovarian cancer ascites environment
- HuR-dependent SOD2 protein synthesis is an early adaptation to anchorage-independence
- PVT1 is a stress-responsive lncRNA that drives ovarian cancer metastasis and chemoresistance
- Hypoxia-induced inhibin promotes tumor growth and vascular permeability in ovarian cancers
Showing 5 of 28 shared publications
Ben Horst
16 shared publications
- A bioinformatic analysis of the inhibin-betaglycan-endoglin/CD105 network reveals prognostic value in multiple solid tumors
- Hypoxia-induced inhibin promotes tumor growth and vascular permeability in ovarian cancers
- Evolving roles of activins and inhibins in ovarian cancer pathophysiology
- Hypoxia Regulated Inhibin Promotes Tumor Growth and Vascular Permeability By ACVRL1 and CD105 Dependent VE-Cadherin Internalization
- Corrigendum to “Dually modified transmembrane proteoglycans in development and disease” [Cytokine Growth Factor Rev. 39 (2018) 124–136]
Showing 5 of 16 shared publications
Eugenia V. Broude
University of South Carolina (US)
15 shared publications
- Depletion of COPI in cancer cells: the role of reactive oxygen species in the induction of lipid accumulation, noncanonical lipophagy and apoptosis
- Anoikis resistance and metastasis of ovarian cancer can be overcome by CDK8/19 Mediator kinase inhibition
- Abstract B058: Targeting mediator kinase CDK8/19 potentiates chemotherapeutic responses, reverses tumor growth, and prolongs survival from ovarian clear cell carcinoma
- Targeting Mediator Kinase Cyclin-Dependent Kinases 8/19 Potentiates Chemotherapeutic Responses, Reverses Tumor Growth, and Prolongs Survival from Ovarian Clear Cell Carcinoma
- Figure S3 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
Showing 5 of 15 shared publications
Laura M. Jenkins
University of South Carolina (US)
14 shared publications
- Glycosaminoglycan modifications of betaglycan regulate ectodomain shedding to fine-tune TGF-β signaling responses in ovarian cancer
- Elucidating the Impact of Betaglycan Glycosaminoglycan Chain Modification on Ectodomain Shedding and Cell Signaling in Ovarian Cancer
- Corrigendum to “Dually modified transmembrane proteoglycans in development and disease” [Cytokine Growth Factor Rev. 39 (2018) 124–136]
- Figure S3 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Table S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
Showing 5 of 14 shared publications
Rebecca C. Arend
University of Alabama (US)
13 shared publications
- TGFβ signaling networks in ovarian cancer progression and plasticity
- Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer
- Emerging perspectives on growth factor metabolic relationships in the ovarian cancer ascites environment
- PVT1 is a stress-responsive lncRNA that drives ovarian cancer metastasis and chemoresistance
- Targeted therapy in high grade serous ovarian Cancer: A literature review
Showing 5 of 13 shared publications
Balázs Győrffy
12 shared publications
- A bioinformatic analysis of the inhibin-betaglycan-endoglin/CD105 network reveals prognostic value in multiple solid tumors
- Figure S3 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Table S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Figure S4 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Figure S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
Showing 5 of 12 shared publications
Priyanka Singh
11 shared publications
- Figure S3 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Table S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Figure S4 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Figure S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Table S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
Showing 5 of 11 shared publications
Victoria Alers
11 shared publications
- Figure S3 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Table S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Figure S4 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Figure S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Table S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
Showing 5 of 11 shared publications
Shrikant Pradhan
11 shared publications
- Figure S3 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Table S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Figure S4 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Figure S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Table S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
Showing 5 of 11 shared publications
Tapasya Srivastava
11 shared publications
- Figure S3 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Table S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Figure S4 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Figure S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
- Table S1 from Inhibin Is a Novel Paracrine Factor for Tumor Angiogenesis and Metastasis
Showing 5 of 11 shared publications
Mehri Monavarian
University of Alabama at Birmingham (US)
8 shared publications
- TGFβ signaling networks in ovarian cancer progression and plasticity
- Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer
- Emerging perspectives on growth factor metabolic relationships in the ovarian cancer ascites environment
- PVT1 is a stress-responsive lncRNA that drives ovarian cancer metastasis and chemoresistance
- Reciprocal epigenetic Sox2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer
Showing 5 of 8 shared publications
Alex Seok Choi
University of Alabama at Birmingham (US)
8 shared publications
- A bioinformatic analysis of the inhibin-betaglycan-endoglin/CD105 network reveals prognostic value in multiple solid tumors
- PVT1 is a stress-responsive lncRNA that drives ovarian cancer metastasis and chemoresistance
- Hypoxia-induced inhibin promotes tumor growth and vascular permeability in ovarian cancers
- Activin levels correlate with lymphocytic infiltration in epithelial ovarian cancer
- PVT1, a YAP1 dependent stress responsive lncRNA drives ovarian cancer metastasis and chemoresistance
Showing 5 of 8 shared publications
Tasmia Ahmed
University of Arizona (US)
8 shared publications
- βIV-spectrin as a stalk cell-intrinsic regulator of VEGF signaling
- EPDR1 is a noncanonical effector of insulin-mediated angiogenesis regulated by an endothelial-specific TGF-β receptor complex
- Endothelial tip/stalk cell selection requires BMP9-induced β<sub>IV</sub>-spectrin expression during sprouting angiogenesis
- Beta <scp>IV</scp> spectrin inhibits the metastatic growth of melanoma by suppressing <scp>VEGFR2</scp>‐driven tumor angiogenesis
- Extracellular signals induce dynamic ER remodeling through αTAT1-dependent microtubule acetylation
Showing 5 of 8 shared publications
Paola Cruz Flores
University of Arizona (US)
8 shared publications
- βIV-spectrin as a stalk cell-intrinsic regulator of VEGF signaling
- EPDR1 is a noncanonical effector of insulin-mediated angiogenesis regulated by an endothelial-specific TGF-β receptor complex
- Endothelial tip/stalk cell selection requires BMP9-induced β<sub>IV</sub>-spectrin expression during sprouting angiogenesis
- Beta <scp>IV</scp> spectrin inhibits the metastatic growth of melanoma by suppressing <scp>VEGFR2</scp>‐driven tumor angiogenesis
- Extracellular signals induce dynamic ER remodeling through αTAT1-dependent microtubule acetylation
Showing 5 of 8 shared publications
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