Leanna M. Delhey
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Also affiliated: Dartmouth College (2013); Dartmouth–Hitchcock Medical Center (2013); Arkansas Children's Hospital (2015–2016); The University of Texas at San Antonio Health Science Center (2013); University of Michigan (2023–2026); National Liver Institute (2018); Arkansas Children's Research Institute (2016–2025); Menoufia University (2018)
Research Areas
Biomedical Subjects
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Biography and Research Information
OverviewAI-generated summary
Leanna M. Delhey's research focuses on understanding and addressing neurological and psychiatric conditions, with a significant emphasis on autism spectrum disorder (ASD) and related developmental pathways. Her work investigates the role of biological factors, such as mitochondrial function and the impact of environmental influences like prenatal air pollution, in neurodevelopment and behavior. Delhey has explored potential therapeutic interventions, including the use of N-acetylcysteine, folinic acid, and intravenous immunoglobulin, in various clinical and preclinical studies.
Her publications include a systematic review on N-acetylcysteine in psychiatry and neurology, and several studies examining the effects of specific compounds like butyrate and propionic acid on mitochondrial function in cell lines relevant to autism. She has also investigated the impact of folate receptor alpha autoantibodies and the potential of folinic acid to improve verbal communication in children with ASD. Delhey's research network includes collaborators from the University of Arkansas for Medical Sciences, such as Shannon Rose, Elisabet Børsheim, Robert R. Delongchamp, and Christina Joshua, with whom she has co-authored multiple publications.
With an h-index of 21 and over 1,900 citations across 54 publications, Delhey's scholarly contributions reflect a sustained engagement with complex health science topics. Her recent work, including a 2020 publication on prenatal air pollution and ASD, indicates continued activity and relevance in her field, with recent publications extending into 2026.
Metrics
- h-index: 21
- Publications: 55
- Citations: 1,934
Selected Publications
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Cancer and all-cause mortality among United States union poultry workers (2026)
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Risk of Mortality From Esophageal Cancer Among US Poultry Workers, 1950−2019 (2025)
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The association between working with poultry and esophageal cancer mortality; a case-cohort study (2022)
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Air Pollution and Maximum Temperature Are Associated with Neurodevelopmental Regressive Events in Autism Spectrum Disorder (2022)
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Metabolomic Signatures of Autism Spectrum Disorder (2022)
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Effect of excess weight and insulin resistance on DNA methylation in prepubertal children (2022)
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Redox Imbalance and Methylation Disturbances in Early Childhood Obesity (2021)
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Prenatal air pollution influences neurodevelopment and behavior in autism spectrum disorder by modulating mitochondrial physiology (2020)
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Early life metal exposure dysregulates cellular bioenergetics in children with regressive autism spectrum disorder (2020)
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Metabolic syndrome and P-wave duration in the American population (2020)
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Biological Pathways of Long‐Term Visit‐to‐Visit Blood Pressure Variability in the American Population: Cardiovascular Health Study and Women’s Health Initiatives (2020)
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The difference between hypertension determined by self-report versus examination in the adult population of the USA: Continuous NHANES 1999–2016 (2019)
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The Influence of Diabetes Status on the Rate of Cataract Surgery Following Pars Plana Vitrectomy (2019)
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The association of metabolic syndrome and QRS|T angle in US adults (NHANES III) (2019)
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Inheritance of HLA-Cw7 Associated With Autism Spectrum Disorder (ASD) (2019)
Collaboration Network
Top Collaborators
- Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Prenatal air pollution influences neurodevelopment and behavior in autism spectrum disorder by modulating mitochondrial physiology
- Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups
Showing 5 of 19 shared publications
- Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review
- Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Prenatal air pollution influences neurodevelopment and behavior in autism spectrum disorder by modulating mitochondrial physiology
Showing 5 of 18 shared publications
- Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Prenatal air pollution influences neurodevelopment and behavior in autism spectrum disorder by modulating mitochondrial physiology
- Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups
Showing 5 of 16 shared publications
- Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Prenatal air pollution influences neurodevelopment and behavior in autism spectrum disorder by modulating mitochondrial physiology
- Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups
- Early life metal exposure dysregulates cellular bioenergetics in children with regressive autism spectrum disorder
Showing 5 of 14 shared publications
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Prenatal air pollution influences neurodevelopment and behavior in autism spectrum disorder by modulating mitochondrial physiology
- Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups
- Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder
Showing 5 of 10 shared publications
- Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups
- Intravenous immunoglobulin for the treatment of autoimmune encephalopathy in children with autism
- Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder
Showing 5 of 8 shared publications
- The association of metabolic syndrome and QRS|T angle in US adults (NHANES III)
- Metabolic syndrome and P-wave duration in the American population
- The relation of blood lead and QRS-T angle in American adults
- The difference between hypertension determined by self-report versus examination in the adult population of the USA: Continuous NHANES 1999–2016
- Association Between Urinary Cadmium and QRS|T Angle Among Adults in the United States
Showing 5 of 8 shared publications
- Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups
- Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder
- The Effect of Mitochondrial Supplements on Mitochondrial Activity in Children with Autism Spectrum Disorder
Showing 5 of 7 shared publications
- Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups
- Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder
Showing 5 of 7 shared publications
- The association of metabolic syndrome and QRS|T angle in US adults (NHANES III)
- Metabolic syndrome and P-wave duration in the American population
- The Influence of Diabetes Status on the Rate of Cataract Surgery Following Pars Plana Vitrectomy
- The relation of blood lead and QRS-T angle in American adults
- The difference between hypertension determined by self-report versus examination in the adult population of the USA: Continuous NHANES 1999–2016
Showing 5 of 7 shared publications
- Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Intravenous immunoglobulin for the treatment of autoimmune encephalopathy in children with autism
- Multivariate techniques enable a biochemical classification of children with autism spectrum disorder versus typically‐developing peers: A comparison and validation study
- Comparison of Treatment for Metabolic Disorders Associated with Autism:Reanalysis of Three Clinical Trials
Showing 5 of 6 shared publications
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Prenatal air pollution influences neurodevelopment and behavior in autism spectrum disorder by modulating mitochondrial physiology
- Multivariate techniques enable a biochemical classification of children with autism spectrum disorder versus typically‐developing peers: A comparison and validation study
- Comparison of Treatment for Metabolic Disorders Associated with Autism:Reanalysis of Three Clinical Trials
- Comparison of Three Clinical Trial Treatments for Autism Spectrum Disorder Through Multivariate Analysis of Changes in Metabolic Profiles and Adaptive Behavior
- The association of metabolic syndrome and QRS|T angle in US adults (NHANES III)
- The relation of blood lead and QRS-T angle in American adults
- Association Between Urinary Cadmium and QRS|T Angle Among Adults in the United States
- Biological Pathways of Long‐Term Visit‐to‐Visit Blood Pressure Variability in the American Population: Cardiovascular Health Study and Women’s Health Initiatives
- The association of metabolic syndrome and QRS|T angle in US adults (NHANES III)
- The relation of blood lead and QRS-T angle in American adults
- Association Between Urinary Cadmium and QRS|T Angle Among Adults in the United States
- Biological Pathways of Long‐Term Visit‐to‐Visit Blood Pressure Variability in the American Population: Cardiovascular Health Study and Women’s Health Initiatives
- Metabolic syndrome and P-wave duration in the American population
- The relation of blood lead and QRS-T angle in American adults
- Association Between Urinary Cadmium and QRS|T Angle Among Adults in the United States
- Biological Pathways of Long‐Term Visit‐to‐Visit Blood Pressure Variability in the American Population: Cardiovascular Health Study and Women’s Health Initiatives
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