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Biography and Research Information
OverviewAI-generated summary
Shannon Rose's research focuses on understanding the biological underpinnings of Autism Spectrum Disorder (ASD), with a particular emphasis on the role of mitochondria and oxidative stress. Her work investigates how cellular processes, such as mitochondrial morphology and respiratory chain function, are altered in individuals with ASD. Rose also explores the potential influence of prenatal environmental factors on ASD development, examining physiological mediators and their connection to redox imbalance and methylation disturbances.
Her research group has published on metabolomic signatures in ASD and the interplay between microRNA and mRNA expression profiles, identifying novel targets and networks associated with the condition. Rose also investigates related health issues, including redox imbalance and methylation disturbances in early childhood obesity. Her work contributes to a growing body of evidence exploring the complex biological pathways involved in neurodevelopmental disorders and associated health conditions, aiming to inform personalized approaches to evaluation and treatment.
Metrics
- h-index: 34
- Publications: 91
- Citations: 5,116
Selected Publications
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Mitochondrial respiratory function in human platelets: Influence of sample preparation, assay buffer, and instrumental platform (2025)
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Correlating maternal and cord-blood inflammatory markers and BDNF with human fetal brain activity recorded by magnetoencephalography: An exploratory study (2024)
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Platelets, inflammation, and purinergic receptors in chronic kidney disease (2024)
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Regulatory T cells and bioenergetics of peripheral blood mononuclear cells linked to pediatric obesity (2024)
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Correlation of fetal heart rate dynamics to inflammatory markers and brain-derived neurotrophic factor during pregnancy (2024)
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Nitrosative Stress in Autism: Supportive Evidence and Implications for Mitochondrial Dysfunction (2024)
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Circulating microRNA levels differ in the early stages of insulin resistance in prepubertal children with obesity (2022)
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Air Pollution and Maximum Temperature Are Associated with Neurodevelopmental Regressive Events in Autism Spectrum Disorder (2022)
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Metabolomic Signatures of Autism Spectrum Disorder (2022)
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Blood RNA Sequencing Indicates Upregulated BATF2 and LY6E and Downregulated ISG15 and MT2A Expression in Children with Autism Spectrum Disorder (2022)
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Integrated microRNA–mRNA Expression Profiling Identifies Novel Targets and Networks Associated with Autism (2022)
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Effect of excess weight and insulin resistance on DNA methylation in prepubertal children (2022)
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A Personalized Approach to Evaluating and Treating Autism Spectrum Disorder (2022)
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Blood RNA Sequencing Confirms Upregulated BATF2 and FCGR1A Expression in Children with Autism Spectrum Disorder (2021)
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MicroRNA Expression Profiles in Autism Spectrum Disorder: Role for miR-181 in Immunomodulation (2021)
Collaboration Network
Top Collaborators
Richard E. Frye
15 shared publications
- Metabolomic Signatures of Autism Spectrum Disorder
- Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder
- Mitochondria May Mediate Prenatal Environmental Influences in Autism Spectrum Disorder
- Physiological mediators of prenatal environmental influences in autism spectrum disorder
- MicroRNA Expression Profiles in Autism Spectrum Disorder: Role for miR-181 in Immunomodulation
Showing 5 of 15 shared publications
Leanna Delhey
University of Michigan–Ann Arbor (US)
8 shared publications
- Metabolomic Signatures of Autism Spectrum Disorder
- Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder
- Redox Imbalance and Methylation Disturbances in Early Childhood Obesity
- Circulating microRNA levels differ in the early stages of insulin resistance in prepubertal children with obesity
- Effect of excess weight and insulin resistance on DNA methylation in prepubertal children
Showing 5 of 8 shared publications
Elisabet Børsheim
Arkansas Children's Hospital
7 shared publications
In database
- Redox Imbalance and Methylation Disturbances in Early Childhood Obesity
- Circulating microRNA levels differ in the early stages of insulin resistance in prepubertal children with obesity
- Effect of excess weight and insulin resistance on DNA methylation in prepubertal children
- Enhanced mitochondrial respiration in peripheral blood mononuclear cells ( <scp>PBMCs</scp> ) from young children with overweight/obesity and insulin resistance
- Mitochondrial Respiratory Function in Human Platelets: Influence of Sample Preparation, Assay Buffer and Instrumental Platform
Showing 5 of 7 shared publications
Sirish C. Bennuri
University of Arkansas Medical Center (US)
5 shared publications
- Redox Imbalance and Methylation Disturbances in Early Childhood Obesity
- MicroRNA Expression Profiles in Autism Spectrum Disorder: Role for miR-181 in Immunomodulation
- Effect of excess weight and insulin resistance on DNA methylation in prepubertal children
- Blood RNA Sequencing Confirms Upregulated BATF2 and FCGR1A Expression in Children with Autism Spectrum Disorder
- Mitochondrial Respiratory Function in Human Platelets: Influence of Sample Preparation, Assay Buffer and Instrumental Platform
Patricia Porter‐Gill
Arkansas Children's Hospital (US)
5 shared publications
- MicroRNA Expression Profiles in Autism Spectrum Disorder: Role for miR-181 in Immunomodulation
- Integrated microRNA–mRNA Expression Profiling Identifies Novel Targets and Networks Associated with Autism
- Circulating microRNA levels differ in the early stages of insulin resistance in prepubertal children with obesity
- Transcriptomic Signatures of Mitochondrial Dysfunction in Autism: Integrated mRNA and microRNA Profiling
- Transcriptomic Signatures of Mitochondrial Dysfunction in Autism: Integrated mRNA and microRNA Profiling
Eugénia Carvalho
University of Coimbra (PT)
4 shared publications
- Redox Imbalance and Methylation Disturbances in Early Childhood Obesity
- Circulating microRNA levels differ in the early stages of insulin resistance in prepubertal children with obesity
- Effect of excess weight and insulin resistance on DNA methylation in prepubertal children
- Enhanced mitochondrial respiration in peripheral blood mononuclear cells ( <scp>PBMCs</scp> ) from young children with overweight/obesity and insulin resistance
Sandra McCullough
Arkansas Children's Hospital (US)
4 shared publications
- MicroRNA Expression Profiles in Autism Spectrum Disorder: Role for miR-181 in Immunomodulation
- Integrated microRNA–mRNA Expression Profiling Identifies Novel Targets and Networks Associated with Autism
- Transcriptomic Signatures of Mitochondrial Dysfunction in Autism: Integrated mRNA and microRNA Profiling
- Transcriptomic Signatures of Mitochondrial Dysfunction in Autism: Integrated mRNA and microRNA Profiling
Pritmohinder S. Gill
Arkansas Children's Hospital
4 shared publications
In database
- MicroRNA Expression Profiles in Autism Spectrum Disorder: Role for miR-181 in Immunomodulation
- Integrated microRNA–mRNA Expression Profiling Identifies Novel Targets and Networks Associated with Autism
- Transcriptomic Signatures of Mitochondrial Dysfunction in Autism: Integrated mRNA and microRNA Profiling
- Transcriptomic Signatures of Mitochondrial Dysfunction in Autism: Integrated mRNA and microRNA Profiling
Patrick J. McCarty
Tulane University (US)
4 shared publications
- Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder
- Bioenergetic signatures of neurodevelopmental regression
- Time dependent changes in the bioenergetics of peripheral blood mononuclear cells: processing time, collection tubes and cryopreservation effects.
- Air Pollution and Maximum Temperature Are Associated with Neurodevelopmental Regressive Events in Autism Spectrum Disorder
Reid D. Landes
University of Arkansas for Medical Sciences (US)
4 shared publications
- Effect of excess weight and insulin resistance on DNA methylation in prepubertal children
- Regulatory T cells and bioenergetics of peripheral blood mononuclear cells linked to pediatric obesity
- Enhanced mitochondrial respiration in peripheral blood mononuclear cells ( <scp>PBMCs</scp> ) from young children with overweight/obesity and insulin resistance
- Circulating Immune Cell Metabolism Is Associated With Body Mass Index and Insulin Resistance in Children and Adolescents
Craig Porter
Arkansas Children's Hospital
4 shared publications
In database
- Platelets, inflammation, and purinergic receptors in chronic kidney disease
- Mitochondrial Respiratory Function in Human Platelets: Influence of Sample Preparation, Assay Buffer and Instrumental Platform
- 791 Glycolysis in leukocytes is linked to serum inflammatory burden in chronic kidney disease
- Mitochondrial respiratory function in human platelets: Influence of sample preparation, assay buffer, and instrumental platform
Janet Cakir
North Carolina State University (US)
3 shared publications
- Mitochondria May Mediate Prenatal Environmental Influences in Autism Spectrum Disorder
- Physiological mediators of prenatal environmental influences in autism spectrum disorder
- Air Pollution and Maximum Temperature Are Associated with Neurodevelopmental Regressive Events in Autism Spectrum Disorder
Raymond F. Palmer
The University of Texas Health Science Center at San Antonio (US)
3 shared publications
- Mitochondria May Mediate Prenatal Environmental Influences in Autism Spectrum Disorder
- Physiological mediators of prenatal environmental influences in autism spectrum disorder
- Air Pollution and Maximum Temperature Are Associated with Neurodevelopmental Regressive Events in Autism Spectrum Disorder
Christine Austin
Icahn School of Medicine at Mount Sinai (US)
3 shared publications
- Mitochondria May Mediate Prenatal Environmental Influences in Autism Spectrum Disorder
- Physiological mediators of prenatal environmental influences in autism spectrum disorder
- Air Pollution and Maximum Temperature Are Associated with Neurodevelopmental Regressive Events in Autism Spectrum Disorder
Paul Curtin
Icahn School of Medicine at Mount Sinai (US)
3 shared publications
- Mitochondria May Mediate Prenatal Environmental Influences in Autism Spectrum Disorder
- Physiological mediators of prenatal environmental influences in autism spectrum disorder
- Air Pollution and Maximum Temperature Are Associated with Neurodevelopmental Regressive Events in Autism Spectrum Disorder
Similar Researchers
Based on overlapping research topics
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