R
Rebecca Wynne Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
faculty
19 h-index
33 pubs
1,459 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Rebecca Wynne's research investigates the genotoxicity of various chemical aerosols using human in vitro airway tissue models. Her work includes assessing DNA damage with the CometChip assay and evaluating mutagenesis using Duplex Sequencing. Recent publications focus on the toxicity of glutaraldehyde and ortho-phthalaldehyde aerosols in these models, comparing in vitro results with standard genotoxicity assays. Wynne also studies the accumulation of somatic cell mutations in airway cultures treated with ethyl methanesulfonate and has explored the role of alcohol consumption in promoting diethylnitrosamine-induced hepatocarcinogenesis in male mice through the Wnt/β-catenin signaling pathway.
Wynne collaborates with researchers including Thomas M. Badger and Kelly E. Mercer from the National Center for Toxicological Research. Her scholarship metrics include an h-index of 19, with 31 total publications and 1,442 total citations.
Metrics
- h-index: 19
- Publications: 33
- Citations: 1,459
Selected Publications
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Comparative genotoxicity assessment of ortho-phthalaldehyde using human in vitro organotypic airway epithelial cultures and standard in vitro genotoxicity assays (2026)
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Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations (2024)
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Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model (2022)
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Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing (2021)
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Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model (2021)
Collaboration Network
Top Collaborators
Kelly E. Mercer
6 shared publications
In database
- Supplementary Table 2 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 1 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Data from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 2 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 1 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
Showing 5 of 6 shared publications
Leah Hennings
6 shared publications
- Supplementary Table 2 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 1 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Data from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 2 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 1 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
Showing 5 of 6 shared publications
Keith Lai
6 shared publications
- Supplementary Table 2 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 1 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Data from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 2 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 1 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
Showing 5 of 6 shared publications
Mario A. Cleves
6 shared publications
- Supplementary Table 2 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 1 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Data from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 2 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 1 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
Showing 5 of 6 shared publications
Thomas M. Badger
6 shared publications
In database
- Supplementary Table 2 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 1 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Data from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 2 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 1 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
Showing 5 of 6 shared publications
Martin J. J. Ronis
6 shared publications
- Supplementary Table 2 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 1 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Data from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 2 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 1 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
Showing 5 of 6 shared publications
Levan Muskhelishvili
National Center for Toxicological Research (US)
4 shared publications
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Kelly J. Davis
National Center for Toxicological Research (US)
4 shared publications
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Xuefei Cao
United States Food and Drug Administration
4 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Neha Sharma
4 shared publications
- Supplementary Table 2 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Supplementary Table 1 from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Data from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
- Data from Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis in Male Mice through Activation of the Wnt/β-Catenin Signaling Pathway
Yiying Wang
National Center for Toxicological Research (US)
3 shared publications
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Robert H. Heflich
National Center for Toxicological Research
3 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
- Comparative genotoxicity assessment of ortho-phthalaldehyde using human in vitro organotypic airway epithelial cultures and standard in vitro genotoxicity assays
Qiangen Wu
National Center for Toxicological Research
2 shared publications
In database
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
Diego Rua
Office of Science (US)
2 shared publications
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
Roberta A. Mittelstaedt
National Center for Toxicological Research
2 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
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