Match tier
Likely match
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-15
R
Rebecca Wynne
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
Researcher
Also affiliated: Arkansas Children's Hospital (2010–2018); United States Food and Drug Administration (2021–2024); Arkansas Children's Nutrition Center (2010–2014); California State University, Long Beach (2012)
Faculty Researcher
19 h-index
33 pubs
1,485 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Rebecca Wynne's research focuses on assessing the genotoxicity and pulmonary toxicity of various chemical agents using human in vitro models. Her work has investigated the potential damage caused by glutaraldehyde and ortho-phthalaldehyde aerosols in human airway tissue models, employing methods like the CometChip assay and Duplex Sequencing to detect DNA damage and mutations. Wynne has also examined the effects of repeat chemical treatments on somatic cell mutations in these airway cultures. Additionally, her research has explored the role of alcohol consumption in promoting diethylnitrosamine-induced hepatocarcinogenesis in male mice, specifically through the activation of the Wnt/β-catenin signaling pathway.
Wynne collaborates with researchers from the National Center for Toxicological Research, including Kelly E. Mercer, Xuefei Cao, and Robert H. Heflich, and also with Thomas M. Badger from the University of Arkansas for Medical Sciences. She has authored 33 publications and has an h-index of 19 with 1,466 citations.
Metrics
- h-index: 19
- Publications: 33
- Citations: 1,485
Selected Publications
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Comparative genotoxicity assessment of ortho-phthalaldehyde using human in vitro organotypic airway epithelial cultures and standard in vitro genotoxicity assays (2026)
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Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations (2024)
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Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model (2022)
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Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing (2021)
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Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model (2021)
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Inheritance of HLA-Cw7 Associated With Autism Spectrum Disorder (ASD) (2019)
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Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism (2018)
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Bioenergetic variation is related to autism symptomatology (2017)
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Oxidative Stress Challenge Uncovers Trichloroacetaldehyde Hydrate-Induced Mitoplasticity in Autistic and Control Lymphoblastoid Cell Lines (2017)
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Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder (2017)
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Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study (2016)
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Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial (2016)
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Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines (2016)
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Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups (2016)
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Increased Susceptibility to Ethylmercury-Induced Mitochondrial Dysfunction in a Subset of Autism Lymphoblastoid Cell Lines (2015)
Collaboration Network
Top Collaborators
Levan Muskhelishvili
National Center for Toxicological Research (US)
4 shared publications
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Kelly J. Davis
National Center for Toxicological Research (US)
4 shared publications
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Xuefei Cao
United States Food and Drug Administration
4 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Yiying Wang
National Center for Toxicological Research (US)
3 shared publications
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Robert H. Heflich
National Center for Toxicological Research
3 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
- Comparative genotoxicity assessment of ortho-phthalaldehyde using human in vitro organotypic airway epithelial cultures and standard in vitro genotoxicity assays
Qiangen Wu
National Center for Toxicological Research
2 shared publications
In database
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
Diego Rua
Office of Science (US)
2 shared publications
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
Roberta A. Mittelstaedt
National Center for Toxicological Research
2 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Ying Chen
United States Food and Drug Administration
2 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Timothy W. Robison
Center for Drug Evaluation and Research (US)
2 shared publications
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Wei Sun
United States Food and Drug Administration (US)
2 shared publications
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Yuan Le
National Center for Toxicological Research
2 shared publications
In database
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
- Comparative genotoxicity assessment of ortho-phthalaldehyde using human in vitro organotypic airway epithelial cultures and standard in vitro genotoxicity assays
Priya Tripathi
National Center for Toxicological Research (US)
1 shared publication
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
Matthew Bryant
National Center for Toxicological Research
1 shared publication
In database
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
Yiying Wang
National Center for Toxicological Research
1 shared publication
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
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